Diabetes Care:血栓切除术后急性大血管闭塞性卒中合并糖尿病患者卒中前血糖控制与功能结局的关系

2021-08-22 MedSci原创 MedSci原创

卒中前血糖控制目标HbA1c≤7.0%可能有益于接受IAT治疗的大血管闭塞性卒中合并糖尿病患者的神经功能恢复。

近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,该研究旨在评估卒中前血糖控制是否与接受动脉内血栓切除术(IAT)的急性大血管闭塞性卒中合并糖尿病患者的功能结局相关。


研究人员从来自韩国卒中临床研究中心注册中心纳入了2009年1月至2020年3月期间接受IAT的紧急大血管闭塞性卒中合并糖尿病患者。研究人员评估了入院时HbA1c水平与功能结局(卒中后3个月的改良Rankin量表)之间的关联。


该研究共分析了1351名患者。与HbA1c水平较低的患者相比,入院时HbA1c水平较高的患者早期神经功能恶化更常见(根据HbA1c五分位数,P=0.02,根据HbA1c为7.0%的临界值,P=0.003)。

入院时较高的HbA1c水平与良好功能结局的几率降低显著相关。在根据年龄、性别、卒中亚型、闭塞部位、再通程度、溶栓方式、从症状出现到腹股沟穿刺时间和治疗期划分的亚组中均一致地观察到了这种关联。
 
由此可见,卒中前血糖控制目标HbA1c≤7.0%可能有益于接受IAT治疗的大血管闭塞性卒中合并糖尿病患者的神经功能恢复,无论卒中亚型、静脉溶栓、闭塞部位、再通程度和治疗周期如何。

原始出处:
 
Jun Young Chang,et al.Prestroke Glucose Control and Functional Outcome in Patients With Acute Large Vessel Occlusive Stroke and Diabetes After Thrombectomy.Diabetes care.2021.https://doi.org/10.2337/dc21-0271

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    2021-12-10 kkunny
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  5. 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Metabolism:中国人群碳水化合物摄入量和新发糖尿病风险的相关性

碳水化合物摄入量占总摄入能量的 49-56% 时患糖尿病的风险最低,但馒头、面条、蛋糕、煎饼等低质量碳水化合物摄入越多,糖尿病风险越高!

Metabolism:非酒精性脂肪肝会增加年轻人患糖尿病的风险

NAFLD与年轻人患糖尿病的风险增加5倍有关。这些结果表明年轻人患糖尿病的具有独立的高风险。

FDA批准FreeStyle Libre 2 App用于糖尿病管理

糖尿病管理一直是慢病管理领域的热点。

Eur Heart J:糖尿病合并冠状动脉疾病患者经皮或手术血运重建术后10年全因死亡比较

无论是否伴有糖尿病,PCI与CABG对3VD和/或LMCAD患者10年全因死亡的治疗效果相似。然而,在接受胰岛素治疗的糖尿病患者中,CABG可能有生存获益。

Diabetes Care:减肥还要靠脑子!低卡路里饮食与胃旁路手术大脑激活状态居然不同!

肥胖症和2型糖尿病(T2DM)是我们这个时代最大的全球健康挑战之一。

J Am Soc Nephrol:肾移植术后早期基础胰岛素治疗与标准护理在预防糖尿病上的效果对比如何?

来自肾脏、肝脏、肺和心脏移植受体的数据显示,移植后诊断的糖尿病(DM)与死亡率和心血管事件有关。移植后DM(PTDM)是一种独特的糖尿病形式,在肾脏移植受者(KTRs)中研究的最为透彻。KTRs在移植