JACC:粪肠球菌菌血症患者感染性心内膜炎发病率较高

2019-07-22 不详 MedSci原创

粪肠球菌是导致感染性心内膜炎(IE)第三常见的病原菌。但是目前尚缺乏系统的前瞻性超声心动图研究来检查粪肠球菌菌血症患者的IE患病率。本研究的目的旨在评估IE患者中粪肠球菌菌血症的发病率,次要目的是探索IE的预测因子。本研究纳入分析了344名粪肠球菌菌血症患者(平均年龄74.2岁,男性占73.5%),并对其进行了心超的检测,其中74%患者接受了经食管超声心动图检测。最终有90名患者确诊为IE,发病率

粪肠球菌是导致感染性心内膜炎(IE)第三常见的病原菌。但是目前尚缺乏系统的前瞻性超声心动图研究来检查粪肠球菌菌血症患者的IE患病率。本研究的目的旨在评估IE患者中粪肠球菌菌血症的发病率,次要目的是探索IE的预测因子。

本研究纳入分析了344名粪肠球菌菌血症患者(平均年龄74.2岁,男性占73.5%),并对其进行了心超的检测,其中74%患者接受了经食管超声心动图检测。最终有90名患者确诊为IE,发病率为26.1±4.6%,IE的危险因素有人工心脏瓣膜([OR]: 3.93; 95% CI: 1.76-8.77; p = 0.001)、社区获得(OR: 3.35; 95% CI: 1.74-6.46; p < 0.001)、未知的入口(OR: 2.36; 95% CI: 1.26-4.40; p = 0.007)、单微生物菌血症(OR: 2.73; 95% CI: 1.23-6.05; p = 0.013)和免疫抑制(OR: 2.82; 95% CI: 1.20-6.58; p = 0.017)。

研究结果显示,在粪肠球菌菌血症患者中,感染性心内膜炎的发病率很高,为26%,提示应对所有粪肠球菌菌血症患者进行超声心动图筛查

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[GetPortalCommentsPageByObjectIdResponse(id=1708538, encodeId=d86b1e0853817, content=<a href='/topic/show?id=4c2d3051535' target=_blank style='color:#2F92EE;'>#内膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30515, encryptionId=4c2d3051535, topicName=内膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=730431558473, createdName=12498974m61暂无昵称, createdTime=Sun Oct 20 06:47:00 CST 2019, time=2019-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823569, encodeId=78c81823569c7, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Sat May 30 07:47:00 CST 2020, time=2020-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1655461, encodeId=e7d71655461a3, content=<a href='/topic/show?id=7c2853311ac' target=_blank style='color:#2F92EE;'>#感染性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53311, encryptionId=7c2853311ac, topicName=感染性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=583d24724321, createdName=charl1234575, createdTime=Fri May 15 12:47:00 CST 2020, time=2020-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1854449, encodeId=5908185444968, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Fri Apr 03 16:47:00 CST 2020, time=2020-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1303956, encodeId=4b2113039560b, content=<a href='/topic/show?id=d1a0880e7c8' target=_blank style='color:#2F92EE;'>#菌血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88077, encryptionId=d1a0880e7c8, topicName=菌血症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e5bc315, createdName=Tommy1949, createdTime=Wed Jul 24 00:47:00 CST 2019, time=2019-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1326274, encodeId=fd8b13262e409, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Wed Jul 24 00:47:00 CST 2019, time=2019-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1350733, encodeId=2cde1350e33f5, content=<a href='/topic/show?id=a32d508e8c3' target=_blank style='color:#2F92EE;'>#心内膜炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50878, encryptionId=a32d508e8c3, topicName=心内膜炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Jul 24 00:47:00 CST 2019, time=2019-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491729, encodeId=bebc1491e292f, content=<a href='/topic/show?id=130a8158305' target=_blank style='color:#2F92EE;'>#肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81583, encryptionId=130a8158305, topicName=肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3c98898784, createdName=psybestwish, createdTime=Wed Jul 24 00:47:00 CST 2019, time=2019-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1531246, encodeId=058b1531246ad, content=<a href='/topic/show?id=3b5ee633753' target=_blank style='color:#2F92EE;'>#粪肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76337, encryptionId=3b5ee633753, topicName=粪肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f72712226339, createdName=hb2012ye, createdTime=Wed Jul 24 00:47:00 CST 2019, time=2019-07-24, status=1, ipAttribution=)]
    2020-04-03 hbwxf
  5. 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  6. 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  7. 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  8. 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非酒精性脂肪肝病(NAFLD)目前已经成为一项全球流行性疾病,预计影响全球约25%~44%的人口。近期发表的一项基于韩国人群的队列研究显示NAFLD患者与那些有健康肝脏的人相比,更容易出现代谢不健康状态。该研究发表在近期的obesity上。

Clinical Chemistry:铁代谢、Hepcidin和心血管死亡率的关系?

贫血是冠心病(CAD)和死亡率的一个危险因素,而目前关于铁代谢对于其的作用仍有争议。 本研究分析了中位随访时间为9.9年的冠状动脉造影患者的铁代谢及其与心血管死亡和总死亡率的关系。在1480例冠心病稳定患者和682例经血管造影排除明显冠心病的患者中测定血红蛋白和铁水平。 研究结果显示,Multivariate-adjusted风险比率(小时)的总死亡率最低四分位数的铁、转铁蛋白饱和度、

盘点:JACC七月第二期研究一览

1.老年低心血管风险的预测因子的探索 · 2019-07-21

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JACC:伊多沙班和华法林对房颤伴肝脏疾病史患者的影响研究

肝脏疾病会增加栓塞和出血风险,且会在直接口服抗凝药临床试验中作为排除标准。本研究的目的旨在评估伊多沙班和华法林对房颤伴肝脏疾病史患者的药代动力学(pk)、药效学(pd)、临床疗效和安全性。本ENGAGE AF-TIMI 48临床试验是一项随机双盲对照试验,肝脏疾病史定义为研究者报告的肝病或随机化转氨酶升高2倍以上。在21105名患者中,有1083名(5.1%)患者有肝脏疾病史,他们各种并发症的发生