Epidemiology :夜间暴露于蓝光可增加患结直肠癌风险

2020-08-02 肿瘤瞭望消化时讯 ioncologyGI

蓝光已成为城市户外照明中越来越普遍的组成部分。它对我们的健康有何影响呢?进行了关于夜间暴露于室外人造光与结直肠癌之间关系的研究。研究发现暴露于蓝光可能会增加患结直肠癌的风险。

蓝光已成为城市户外照明中越来越普遍的组成部分。它对我们的健康有何影响呢?由“la Caixa”基金会支持的巴塞罗那全球健康研究所(ISGlobal)领导的一个团队进行了首次关于夜间暴露于室外人造光与结直肠癌之间关系的研究。研究结果发表在《流行病学》(Epidemiology):暴露于蓝光可能会增加患结直肠癌的风险。

此前的研究已经发现,夜间接触人造光(尤其是蓝光)与各种不良健康影响之间存在关联,包括睡眠紊乱、肥胖和各种癌症风险增加,尤其是夜班工人。蓝光是大多数白色LED和许多平板电脑、手机屏幕发出的可见光光谱的一个范围。ISGlobal早前的一项研究发现,夜间接触蓝光与乳腺癌和前列腺癌风险增加之间存在联系。

结直肠癌是全球继肺癌和乳腺癌的第三个常见癌症。目前,WHO的国际癌症研究机构(IARC)将夜班工作列为可能致癌的工作,夜班工作者乳腺癌、前列腺和结直肠部的风险最高。因此,研究人员应用与之前相同的研究方法,分析了人造光暴露与结直肠癌风险之间的关系。

研究人员分析了通过MCC-Spain项目获得的来自巴塞罗那和马德里的约2000名成人的数据,其中660例患有结直肠癌,其余受分析者从当地人口中随机选取。有夜班工作史者被排除在外。夜间室外人造光的水平根据国际空间站(ISS)的图像确定。

分析结果显示,暴露于蓝光者患结直肠癌的风险比暴露于蓝光较少者高60%。未发现全光谱光与结直肠癌之间存在关联。

研究人员指出,夜间暴露在光线下,特别是蓝光,会减少褪黑激素的产生和分泌,这取决于光线的强度和波长。由于曝光量是由卫星图像估计的,所以本分析未考虑个人行为,例如使用流动百叶窗。而百叶窗在西班牙和其他地中海国家很常见。因此,对暴露量的估计可以解释为人们在室外(西班牙的常见模式)和关上百叶窗上床睡觉前在室内所接触到的光量。

研究人员最后评论道,人们越来越担心光对生态系统和人类健康的影响。关于暴露在光线下的潜在影响的研究仍处于起步阶段,尚需要做更多工作来提供可靠的、基于证据的建议来防止不良后果。

原始出处:

Ariadna Garcia-Saenz, Alejandro Sánchez de Miguel, Ana Espinosa,et al.Association between outdoor light-at-night exposure and colorectal cancer in Spain (MCC-Spain study).Epidemiology. 2020 Jun 24. doi: 10.1097/EDE.0000000000001226.

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    2022-09-02 小小医者

    #蓝光#可增加患#结直肠癌#,这里面奥密真的值得探究

    0

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    2020-12-23 ms3000001705808860

    可怕

    0

  4. 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  5. 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  6. 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    2020-08-30 ms_zhen

    不敢熬夜用电脑写作业了😱

    0

  7. 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GetPortalCommentsPageByObjectIdResponse(id=805843, encodeId=c1c08058438e, content=还是不要熬夜, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b972455532, createdName=1240394fm61暂无昵称, createdTime=Mon Aug 03 05:56:03 CST 2020, time=2020-08-03, status=1, ipAttribution=)]
    2020-08-05 蔡冬里蔡

    干货满满

    0

  8. 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  9. [GetPortalCommentsPageByObjectIdResponse(id=1242648, encodeId=b95e12426489a, content=<a href='/topic/show?id=8878883527c' target=_blank style='color:#2F92EE;'>#蓝光#</a>可增加患<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a>,这里面奥密真的值得探究, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88352, encryptionId=8878883527c, topicName=蓝光), TopicDto(id=78692, encryptionId=493ae869206, topicName=结直肠癌)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/Random/55971dc507c93968175ce7cc1e177b372a83869f.jpg, createdBy=f63e4754896, createdName=小小医者, createdTime=Fri Sep 02 02:45:48 CST 2022, time=2022-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061953, encodeId=c60f206195335, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, 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    2020-08-03 月瘦如眉

    可怕😱

    0

  10. 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    2020-08-03 1240394fm61暂无昵称

    还是不要熬夜

    0

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