JAMA Netw Open:中国膳食烟酸摄入量与新发高血压风险评估

2021-01-29 MedSci原创 MedSci原创

随着社会经济的发展和居民生活方式的改变,高血压已成为影响全球居民健康的重大公共卫生问题。

随着社会经济的发展和居民生活方式的改变,高血压已成为影响全球居民健康的重大公共卫生问题。据《柳叶刀》研究研究报告,1975至到2015年,全球高血压患者从5.94亿增至11亿,其中大多数人生活在发展中国家,2.26亿高血压人口生活在中国。因此,迫切需要识别高危人群,制定有效的一级预防策略扭转高血压上升的趋势。

烟酸,也称为维生素B3,是一种水溶性维生素,是人体必需的维生素。日常饮食中,烟酸主要来源包括谷类,肉类以及蔬菜等。有研究表明,烟酸补充剂可以调节异常的脂质代谢,改善内皮功能,并具有抗氧化和抗炎特性。然而,过量的摄入烟酸对身体会产生不利影响。迄今为止,关于饮食中烟酸摄入与高血压之间关系的研究仍然有限。

近日,发表在JAMA Netw Open杂志的一项研究,研究人员使用来自全国范围内的《中国健康与营养调查》数据,共涉及12243名中国成年人,调查了中国成年人膳食烟酸摄入量与新发高血压之间的关联。膳食摄入量的测量方法是通过连续324小时回顾膳食情况,并结合在家庭层面上进行的3天的膳食称重清单。

结果显示,在平均6.1年的随访中,共有4306名新发高血压患者。膳食烟酸的平均摄入量为14.8mg/d与烟酸的摄入量<12.4 mg/d相比,摄入量在14.316.7 mg/d的成年人发生新发高血压的风险最低。烟酸的摄入量每增加1mg/d,且摄入最高值<15.6 mg/d,新发高血压降低2%,若≥15.6 mg/d,新发高血压增加3%

综上,根据这些结果,中国成年人膳食烟酸摄入量与新发高血压之间存在J型关系,摄入量以15.6 mg/d为拐点,烟酸摄入量在14.316.7 mg/d时患高血压风险最小。本研究结果为维持最佳膳食烟酸摄入水平,为高血压的一级预防提供了一定的证据。

原始出处

Zhuxian Zhang, MD et al.Evaluation of Dietary Niacin and New-Onset Hypertension Among Chinese Adults.JAMA Netw Open. 2021;4(1):e2031669. doi:10.1001/jamanetworkopen.2020.31669

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    2022-01-11 feather89
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    2021-12-26 canlab
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    2021-12-12 lmm397
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    2021-01-31 zhaojie88
  5. [GetPortalCommentsPageByObjectIdResponse(id=1728802, encodeId=55871e2880270, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue Jan 11 14:20:56 CST 2022, time=2022-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1734302, encodeId=a4461e3430291, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12668, encryptionId=d4f412668a4, topicName=NET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7ea033781210, createdName=canlab, createdTime=Sun Dec 26 21:20:56 CST 2021, time=2021-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860685, encodeId=fad5186068553, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Sun Dec 12 19:20:56 CST 2021, time=2021-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1350436, encodeId=ecdf13504363a, content=<a href='/topic/show?id=224a85904ad' target=_blank style='color:#2F92EE;'>#膳食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85904, encryptionId=224a85904ad, topicName=膳食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Jan 31 14:20:56 CST 2021, time=2021-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1414822, encodeId=f0e9141482217, content=<a href='/topic/show?id=683e6e12629' target=_blank style='color:#2F92EE;'>#烟酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67126, encryptionId=683e6e12629, topicName=烟酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c703090847, createdName=zblhy, createdTime=Sun Jan 31 14:20:56 CST 2021, time=2021-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=921249, encodeId=bbba92124904, content=htn得从预防抓起, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Sat Jan 30 05:55:58 CST 2021, time=2021-01-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036426, encodeId=087f103642661, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Sat Jan 30 02:20:56 CST 2021, time=2021-01-30, status=1, ipAttribution=)]
    2021-01-31 zblhy
  6. [GetPortalCommentsPageByObjectIdResponse(id=1728802, encodeId=55871e2880270, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue Jan 11 14:20:56 CST 2022, time=2022-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1734302, encodeId=a4461e3430291, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12668, encryptionId=d4f412668a4, topicName=NET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7ea033781210, createdName=canlab, createdTime=Sun Dec 26 21:20:56 CST 2021, time=2021-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860685, encodeId=fad5186068553, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Sun Dec 12 19:20:56 CST 2021, time=2021-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1350436, encodeId=ecdf13504363a, content=<a href='/topic/show?id=224a85904ad' target=_blank style='color:#2F92EE;'>#膳食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85904, encryptionId=224a85904ad, topicName=膳食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Jan 31 14:20:56 CST 2021, time=2021-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1414822, encodeId=f0e9141482217, content=<a href='/topic/show?id=683e6e12629' target=_blank style='color:#2F92EE;'>#烟酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67126, encryptionId=683e6e12629, topicName=烟酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c703090847, createdName=zblhy, createdTime=Sun Jan 31 14:20:56 CST 2021, time=2021-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=921249, encodeId=bbba92124904, content=htn得从预防抓起, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Sat Jan 30 05:55:58 CST 2021, time=2021-01-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036426, encodeId=087f103642661, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Sat Jan 30 02:20:56 CST 2021, time=2021-01-30, status=1, ipAttribution=)]
    2021-01-30 carrotlyl

    htn得从预防抓起

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1728802, encodeId=55871e2880270, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue Jan 11 14:20:56 CST 2022, time=2022-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1734302, encodeId=a4461e3430291, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12668, encryptionId=d4f412668a4, topicName=NET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7ea033781210, createdName=canlab, createdTime=Sun Dec 26 21:20:56 CST 2021, time=2021-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860685, encodeId=fad5186068553, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Sun Dec 12 19:20:56 CST 2021, time=2021-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1350436, encodeId=ecdf13504363a, content=<a href='/topic/show?id=224a85904ad' target=_blank style='color:#2F92EE;'>#膳食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85904, encryptionId=224a85904ad, topicName=膳食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Jan 31 14:20:56 CST 2021, time=2021-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1414822, encodeId=f0e9141482217, content=<a href='/topic/show?id=683e6e12629' target=_blank style='color:#2F92EE;'>#烟酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67126, encryptionId=683e6e12629, topicName=烟酸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c703090847, createdName=zblhy, createdTime=Sun Jan 31 14:20:56 CST 2021, time=2021-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=921249, encodeId=bbba92124904, content=htn得从预防抓起, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Sat Jan 30 05:55:58 CST 2021, time=2021-01-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036426, encodeId=087f103642661, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Sat Jan 30 02:20:56 CST 2021, time=2021-01-30, status=1, ipAttribution=)]
    2021-01-30 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

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