连续性血液净化在肾综合征出血热患者中的治疗时机及预后分析

2013-11-27 佚名 医学论坛网

近日,中国人民解放军281医院,全军中西医结合治疗肾病中心研究人员发表论文,旨在探讨连续性血液净化(CBP)在肾综合征出血热(HFRS)患者中的治疗时机及预后。研究指出,对合并AKI、MODS的HFRS患者早期行CBP治疗可以改善患者预后。该文发表在2013年第09期《中国中西医结合肾病杂志》上。)【原文下载】 回顾性分析我院近10年以来行连续性血液净化治疗的322例肾综合征出血热患者,按RIF

近日,中国人民解放军281医院,全军中西医结合治疗肾病中心研究人员发表论文,旨在探讨连续性血液净化(CBP)在肾综合征出血热(HFRS)患者中的治疗时机及预后。研究指出,对合并AKI、MODS的HFRS患者早期行CBP治疗可以改善患者预后。该文发表在2013年第09期《中国中西医结合肾病杂志》上。)【原文下载

回顾性分析我院近10年以来行连续性血液净化治疗的322例肾综合征出血热患者,按RIFLE标准分为AKIⅠ期、Ⅱ期和Ⅲ期,并对不同AKI分期患者行连续性静-静脉血液滤过(CVVH)治疗前和治疗24 h后的APACHEⅡ评分、SOFA评分、平均动脉压、氧合指数指标、患者死亡率进行比较。

AKIⅡ期和AKIⅢ期较AKIⅠ期患者的机械通气率、缩血管药物使用率、肝脏衰竭率、ARDS发生率,全身炎症反应和中枢神经系统症状发生率都显著提高(P<0.05)。与CVVH治疗前相比,CVVH治疗24 h后平均动脉压和氧合指数均明显升高(P<0.05),APACHEⅡ评分和SOFA评分在AKIⅠ期和Ⅱ期患者显著降低(P<0.05),在AKIⅢ期患者中变化则差异无统计学意义(P>0.05)。AKIⅢ期患者的医院死亡率显著高于AKIⅠ期和AKIⅡ期患者(P<0.05),AKIⅠ期和AKIⅡ期患者死亡率则差异无统计学意义(P>0.05)。

原文出处

单福军,李鑫宇,刘丹颖 ,马路,常伟琼,张晓青.连续性血液净化在肾综合征出血热患者中的治疗时机及预后分析.《中国中西医结合肾病杂志 》2013, 14(9);【原文下载

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