Eur Heart J:术后房颤与心力衰竭住院风险的关系

2022-07-03 MedSci原创 MedSci原创

在接受心脏和非心脏手术且无心衰病史的患者中,POAF与心衰住院事件相关。这些结果突出了POAF对患者预后的不良影响,并提示POAF可能是鉴别亚临床心衰患者和心衰高危患者的一个标志。

手术后房颤(POAF)发生在40%的心脏手术患者和2%的非心脏手术患者中。在临床实践中,POAF通常被认为是一种相对良性的事件,由手术的压力和随后的儿茶酚胺释放所致。但是POAF与卒中和死亡率相关,而且POAF是否与随后的心力衰竭(HF)住院相关尚不明确。

近日,心血管领域权威杂志Eur Heart J上发表了一篇研究文章,该研究旨在探讨接受心脏和非心脏手术患者POAF与心衰住院发生率之间的关系。

这项回顾性队列研究使用了美国11个州的所有支付人行政索赔数据,纳入了所有非联邦急诊就诊和急性住院。研究人群包括年龄在18岁以上、因手术住院且未确诊心衰的成年人,并使用Cox比例风险回归模型来评估POAF与心衰住院事件之间的关系。

在接受心脏手术的76536例患者中,有14365例(18.8%)发生POAF。在校正的Cox模型中,POAF与心衰住院事件相关[风险比(HR)为1.33;95%置信区间(CI)为1.25-1.41]。在这项敏感性分析中,排除术后1年内心衰的因素,POAF与心衰住院事件相关(HR为1.15;95%CI为1.01-1.31)。在2929854例接受非心脏手术的患者中,23763例(0.8%)患者发生POAF。在经调整的Cox模型中,POAF与心衰住院事件相关(HR为2.02;95%CI为1.94-2.10),包括在敏感性分析中排除手术1年内的HF(HR为1.49;95%可信区间为1.38-1.61)。

由此可见,在接受心脏和非心脏手术且无心衰病史的患者中,POAF与心衰住院事件相关。这些结果突出了POAF对患者预后的不良影响,并提示POAF可能是鉴别亚临床心衰患者和心衰高危患者的一个标志。

 

原始出处:

Parag Goyal,et al.Post-operative atrial fibrillation and risk of heart failure hospitalization.European Heart Journal.2022.https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehac285/6617280

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    2022-07-03 huaguang

    术后房颤发生率还是挺高的

    0

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    2022-07-03 zhaojie88
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    2022-07-03 slcumt

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