NEJM:锌缺乏相关性皮炎-病例报道

2020-10-29 MedSci原创 MedSci原创

缺锌相对容易治疗,需要考虑与难治性特应性皮炎、脓疱疮和其他湿疹性皮肤病的鉴别诊断。这种疾病的根本原因尚未明确,因为母亲的血清锌水平正常。

患者为一名纯母乳喂养的4个月大男孩,因皮疹逐渐恶化6周而就诊。

体格检查发现腹部(如图A所示)、手臂(如图B所示)、腿、尿布区域、脸部和头皮上分布着广泛的、分界明确的红斑以及糜烂性斑块。没有观察到其他异常的身体或发育结果。进行皮肤活检,发现角膜角化不规则和角化不全,颗粒细胞层减少,表皮上层角质形成细胞苍白,提示锌缺乏。实验室检查发现,血清锌水平为226μg/L(3.5μmol/L)(参考范围为600至1200μg/L[9.2至18.4μmol/L]),并诊断为与锌缺乏有关的皮炎。

缺锌相对容易治疗,需要考虑与难治性特应性皮炎、脓疱疮和其他湿疹性皮肤病的鉴别诊断。这种疾病的根本原因尚未明确,因为母亲的血清锌水平正常。

该患儿开始口服硫酸锌补充剂,皮疹在5天内完全消除。继续口服锌补充剂,在初次就诊后一年的随访中,皮疹没有复发。

原始出处:

Sina D. Schröder,et al.Zinc Deficiency–Associated Dermatitis.N Engl J Med.2020;https://www.nejm.org/doi/full/10.1056/NEJMicm2001912

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1837884, encodeId=d50a183e88434, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Mon Sep 27 12:00:41 CST 2021, time=2021-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=956660, encodeId=93f69566609e, content=使用硫酸锌后,患儿症状明显好转,口服补锌剂的疗程大概多久,该何时停药?, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/LMxuvQxWQTTq6icl1IdHUTa99B8HLWs71jxRRyJE8la9yIHkMN5MdJlezl0ic7590PYksUYOOy4MrqkfOia5E5O2A/132, createdBy=e1552482838, createdName=es_Y, createdTime=Tue Apr 13 18:43:44 CST 2021, time=2021-04-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=921839, encodeId=f1d29218391c, content=涨知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=29535177825, createdName=146edeb7m12暂无昵称, createdTime=Mon Feb 01 09:14:50 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895815, encodeId=29d589581520, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab4c5429935, createdName=ms3000000545151012, createdTime=Sat Oct 31 09:02:12 CST 2020, time=2020-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895470, encodeId=380f8954e0fe, content=诊断性治疗😂, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7c585423313, createdName=ms3000000833147554, createdTime=Thu Oct 29 19:19:27 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035471, encodeId=29f710354e10a, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Oct 29 11:00:41 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895367, encodeId=e79489536efd, content=好用, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fae35430026, createdName=小光皮球, createdTime=Thu Oct 29 10:41:38 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895362, encodeId=cece895362b5, content=缺<a href='/topic/show?id=7b1696e06be' target=_blank style='color:#2F92EE;'>#锌#</a>相对容易治疗,需要考虑与难治性<a href='/topic/show?id=c0826e93471' target=_blank style='color:#2F92EE;'>#特应性皮炎#</a>、<a href='/topic/show?id=9a6085204e2' target=_blank style='color:#2F92EE;'>#脓疱疮#</a>和其他<a href='/topic/show?id=e9846644229' target=_blank style='color:#2F92EE;'>#湿疹#</a>性皮肤病的鉴别诊断。问题如何知晓与鉴别?, beContent=null, objectType=article, channel=null, level=null, likeNumber=219, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96706, encryptionId=7b1696e06be, topicName=锌), TopicDto(id=67934, encryptionId=c0826e93471, topicName=特应性皮炎), TopicDto(id=85204, encryptionId=9a6085204e2, topicName=脓疱疮), TopicDto(id=66442, encryptionId=e9846644229, topicName=湿疹)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Thu Oct 29 10:25:42 CST 2020, time=2020-10-29, status=1, ipAttribution=)]
    2021-04-13 es_Y

    使用硫酸锌后,患儿症状明显好转,口服补锌剂的疗程大概多久,该何时停药?

    0

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    2021-02-01 146edeb7m12暂无昵称

    涨知识了

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1837884, encodeId=d50a183e88434, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Mon Sep 27 12:00:41 CST 2021, time=2021-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=956660, encodeId=93f69566609e, content=使用硫酸锌后,患儿症状明显好转,口服补锌剂的疗程大概多久,该何时停药?, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/LMxuvQxWQTTq6icl1IdHUTa99B8HLWs71jxRRyJE8la9yIHkMN5MdJlezl0ic7590PYksUYOOy4MrqkfOia5E5O2A/132, createdBy=e1552482838, createdName=es_Y, createdTime=Tue Apr 13 18:43:44 CST 2021, time=2021-04-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=921839, encodeId=f1d29218391c, content=涨知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=29535177825, createdName=146edeb7m12暂无昵称, createdTime=Mon Feb 01 09:14:50 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895815, encodeId=29d589581520, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab4c5429935, createdName=ms3000000545151012, createdTime=Sat Oct 31 09:02:12 CST 2020, time=2020-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895470, encodeId=380f8954e0fe, content=诊断性治疗😂, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7c585423313, createdName=ms3000000833147554, createdTime=Thu Oct 29 19:19:27 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035471, encodeId=29f710354e10a, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Oct 29 11:00:41 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895367, encodeId=e79489536efd, content=好用, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fae35430026, createdName=小光皮球, createdTime=Thu Oct 29 10:41:38 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895362, encodeId=cece895362b5, content=缺<a href='/topic/show?id=7b1696e06be' target=_blank style='color:#2F92EE;'>#锌#</a>相对容易治疗,需要考虑与难治性<a href='/topic/show?id=c0826e93471' target=_blank style='color:#2F92EE;'>#特应性皮炎#</a>、<a href='/topic/show?id=9a6085204e2' target=_blank style='color:#2F92EE;'>#脓疱疮#</a>和其他<a href='/topic/show?id=e9846644229' target=_blank style='color:#2F92EE;'>#湿疹#</a>性皮肤病的鉴别诊断。问题如何知晓与鉴别?, beContent=null, objectType=article, channel=null, level=null, likeNumber=219, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96706, encryptionId=7b1696e06be, topicName=锌), TopicDto(id=67934, encryptionId=c0826e93471, topicName=特应性皮炎), TopicDto(id=85204, encryptionId=9a6085204e2, topicName=脓疱疮), TopicDto(id=66442, encryptionId=e9846644229, topicName=湿疹)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Thu Oct 29 10:25:42 CST 2020, time=2020-10-29, status=1, ipAttribution=)]
    2020-10-31 ms3000000545151012

    学习了

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1837884, encodeId=d50a183e88434, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Mon Sep 27 12:00:41 CST 2021, time=2021-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=956660, encodeId=93f69566609e, content=使用硫酸锌后,患儿症状明显好转,口服补锌剂的疗程大概多久,该何时停药?, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/LMxuvQxWQTTq6icl1IdHUTa99B8HLWs71jxRRyJE8la9yIHkMN5MdJlezl0ic7590PYksUYOOy4MrqkfOia5E5O2A/132, createdBy=e1552482838, createdName=es_Y, createdTime=Tue Apr 13 18:43:44 CST 2021, time=2021-04-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=921839, encodeId=f1d29218391c, content=涨知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=29535177825, createdName=146edeb7m12暂无昵称, createdTime=Mon Feb 01 09:14:50 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895815, encodeId=29d589581520, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab4c5429935, createdName=ms3000000545151012, createdTime=Sat Oct 31 09:02:12 CST 2020, time=2020-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895470, encodeId=380f8954e0fe, content=诊断性治疗😂, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7c585423313, createdName=ms3000000833147554, createdTime=Thu Oct 29 19:19:27 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035471, encodeId=29f710354e10a, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Oct 29 11:00:41 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895367, encodeId=e79489536efd, content=好用, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fae35430026, createdName=小光皮球, createdTime=Thu Oct 29 10:41:38 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895362, encodeId=cece895362b5, content=缺<a href='/topic/show?id=7b1696e06be' target=_blank style='color:#2F92EE;'>#锌#</a>相对容易治疗,需要考虑与难治性<a href='/topic/show?id=c0826e93471' target=_blank style='color:#2F92EE;'>#特应性皮炎#</a>、<a href='/topic/show?id=9a6085204e2' target=_blank style='color:#2F92EE;'>#脓疱疮#</a>和其他<a href='/topic/show?id=e9846644229' target=_blank style='color:#2F92EE;'>#湿疹#</a>性皮肤病的鉴别诊断。问题如何知晓与鉴别?, beContent=null, objectType=article, channel=null, level=null, likeNumber=219, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96706, encryptionId=7b1696e06be, topicName=锌), TopicDto(id=67934, encryptionId=c0826e93471, topicName=特应性皮炎), TopicDto(id=85204, encryptionId=9a6085204e2, topicName=脓疱疮), TopicDto(id=66442, encryptionId=e9846644229, topicName=湿疹)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Thu Oct 29 10:25:42 CST 2020, time=2020-10-29, status=1, ipAttribution=)]
    2020-10-29 ms3000000833147554

    诊断性治疗😂

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1837884, encodeId=d50a183e88434, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Mon Sep 27 12:00:41 CST 2021, time=2021-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=956660, encodeId=93f69566609e, content=使用硫酸锌后,患儿症状明显好转,口服补锌剂的疗程大概多久,该何时停药?, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/LMxuvQxWQTTq6icl1IdHUTa99B8HLWs71jxRRyJE8la9yIHkMN5MdJlezl0ic7590PYksUYOOy4MrqkfOia5E5O2A/132, createdBy=e1552482838, createdName=es_Y, createdTime=Tue Apr 13 18:43:44 CST 2021, time=2021-04-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=921839, encodeId=f1d29218391c, content=涨知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=29535177825, createdName=146edeb7m12暂无昵称, createdTime=Mon Feb 01 09:14:50 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895815, encodeId=29d589581520, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab4c5429935, createdName=ms3000000545151012, createdTime=Sat Oct 31 09:02:12 CST 2020, time=2020-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895470, encodeId=380f8954e0fe, content=诊断性治疗😂, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7c585423313, createdName=ms3000000833147554, createdTime=Thu Oct 29 19:19:27 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035471, encodeId=29f710354e10a, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Oct 29 11:00:41 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895367, encodeId=e79489536efd, content=好用, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fae35430026, createdName=小光皮球, createdTime=Thu Oct 29 10:41:38 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895362, encodeId=cece895362b5, content=缺<a href='/topic/show?id=7b1696e06be' target=_blank style='color:#2F92EE;'>#锌#</a>相对容易治疗,需要考虑与难治性<a href='/topic/show?id=c0826e93471' target=_blank style='color:#2F92EE;'>#特应性皮炎#</a>、<a href='/topic/show?id=9a6085204e2' target=_blank style='color:#2F92EE;'>#脓疱疮#</a>和其他<a href='/topic/show?id=e9846644229' target=_blank style='color:#2F92EE;'>#湿疹#</a>性皮肤病的鉴别诊断。问题如何知晓与鉴别?, beContent=null, objectType=article, channel=null, level=null, likeNumber=219, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96706, encryptionId=7b1696e06be, topicName=锌), TopicDto(id=67934, encryptionId=c0826e93471, topicName=特应性皮炎), TopicDto(id=85204, encryptionId=9a6085204e2, topicName=脓疱疮), TopicDto(id=66442, encryptionId=e9846644229, topicName=湿疹)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Thu Oct 29 10:25:42 CST 2020, time=2020-10-29, status=1, ipAttribution=)]
    2020-10-29 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1837884, encodeId=d50a183e88434, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Mon Sep 27 12:00:41 CST 2021, time=2021-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=956660, encodeId=93f69566609e, content=使用硫酸锌后,患儿症状明显好转,口服补锌剂的疗程大概多久,该何时停药?, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/LMxuvQxWQTTq6icl1IdHUTa99B8HLWs71jxRRyJE8la9yIHkMN5MdJlezl0ic7590PYksUYOOy4MrqkfOia5E5O2A/132, createdBy=e1552482838, createdName=es_Y, createdTime=Tue Apr 13 18:43:44 CST 2021, time=2021-04-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=921839, encodeId=f1d29218391c, content=涨知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=29535177825, createdName=146edeb7m12暂无昵称, createdTime=Mon Feb 01 09:14:50 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895815, encodeId=29d589581520, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab4c5429935, createdName=ms3000000545151012, createdTime=Sat Oct 31 09:02:12 CST 2020, time=2020-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895470, encodeId=380f8954e0fe, content=诊断性治疗😂, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7c585423313, createdName=ms3000000833147554, createdTime=Thu Oct 29 19:19:27 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035471, encodeId=29f710354e10a, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Oct 29 11:00:41 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895367, encodeId=e79489536efd, content=好用, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fae35430026, createdName=小光皮球, createdTime=Thu Oct 29 10:41:38 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895362, encodeId=cece895362b5, content=缺<a href='/topic/show?id=7b1696e06be' target=_blank style='color:#2F92EE;'>#锌#</a>相对容易治疗,需要考虑与难治性<a href='/topic/show?id=c0826e93471' target=_blank style='color:#2F92EE;'>#特应性皮炎#</a>、<a href='/topic/show?id=9a6085204e2' target=_blank style='color:#2F92EE;'>#脓疱疮#</a>和其他<a href='/topic/show?id=e9846644229' target=_blank style='color:#2F92EE;'>#湿疹#</a>性皮肤病的鉴别诊断。问题如何知晓与鉴别?, beContent=null, objectType=article, channel=null, level=null, likeNumber=219, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96706, encryptionId=7b1696e06be, topicName=锌), TopicDto(id=67934, encryptionId=c0826e93471, topicName=特应性皮炎), TopicDto(id=85204, encryptionId=9a6085204e2, topicName=脓疱疮), TopicDto(id=66442, encryptionId=e9846644229, topicName=湿疹)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Thu Oct 29 10:25:42 CST 2020, time=2020-10-29, status=1, ipAttribution=)]
    2020-10-29 小光皮球

    好用

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1837884, encodeId=d50a183e88434, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Mon Sep 27 12:00:41 CST 2021, time=2021-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=956660, encodeId=93f69566609e, content=使用硫酸锌后,患儿症状明显好转,口服补锌剂的疗程大概多久,该何时停药?, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/LMxuvQxWQTTq6icl1IdHUTa99B8HLWs71jxRRyJE8la9yIHkMN5MdJlezl0ic7590PYksUYOOy4MrqkfOia5E5O2A/132, createdBy=e1552482838, createdName=es_Y, createdTime=Tue Apr 13 18:43:44 CST 2021, time=2021-04-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=921839, encodeId=f1d29218391c, content=涨知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=29535177825, createdName=146edeb7m12暂无昵称, createdTime=Mon Feb 01 09:14:50 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895815, encodeId=29d589581520, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab4c5429935, createdName=ms3000000545151012, createdTime=Sat Oct 31 09:02:12 CST 2020, time=2020-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895470, encodeId=380f8954e0fe, content=诊断性治疗😂, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7c585423313, createdName=ms3000000833147554, createdTime=Thu Oct 29 19:19:27 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035471, encodeId=29f710354e10a, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Oct 29 11:00:41 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895367, encodeId=e79489536efd, content=好用, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fae35430026, createdName=小光皮球, createdTime=Thu Oct 29 10:41:38 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895362, encodeId=cece895362b5, content=缺<a href='/topic/show?id=7b1696e06be' target=_blank style='color:#2F92EE;'>#锌#</a>相对容易治疗,需要考虑与难治性<a href='/topic/show?id=c0826e93471' target=_blank style='color:#2F92EE;'>#特应性皮炎#</a>、<a href='/topic/show?id=9a6085204e2' target=_blank style='color:#2F92EE;'>#脓疱疮#</a>和其他<a href='/topic/show?id=e9846644229' target=_blank style='color:#2F92EE;'>#湿疹#</a>性皮肤病的鉴别诊断。问题如何知晓与鉴别?, beContent=null, objectType=article, channel=null, level=null, likeNumber=219, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96706, encryptionId=7b1696e06be, topicName=锌), TopicDto(id=67934, encryptionId=c0826e93471, topicName=特应性皮炎), TopicDto(id=85204, encryptionId=9a6085204e2, topicName=脓疱疮), TopicDto(id=66442, encryptionId=e9846644229, topicName=湿疹)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Thu Oct 29 10:25:42 CST 2020, time=2020-10-29, status=1, ipAttribution=)]
    2020-10-29 lovetcm

    #锌#相对容易治疗,需要考虑与难治性#特应性皮炎##脓疱疮#和其他#湿疹#性皮肤病的鉴别诊断。问题如何知晓与鉴别?

    0

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