Ann Rheum Dis:1990-2017年全球、地区和国家的骨关节炎负担

2020-05-15 xiangting MedSci原创

OA是一项重大的公共卫生挑战。尽管患病率、发病率和OA导致的YLDs存在明显的国际性差异,但大多数国家的负担正在增加。

这项研究旨在按照年龄、性别和社会人口学指数(SDI;社会人口学综合指标)报道1990至2017年195个国家和地区的骨关节炎(OA)患病率、发病率和残障生存年限(YLDs)的水平和趋势。

使用2017年全球疾病、伤害和危险因素负担研究(GBD)中公开可用的建模数据。通过使用GBD 2017研究中报告的方法对患病率和发病率建模数据进行系统分析,估算了1990年至2017年195个国家和地区的OA负担。所有估算值均表示为每10万人口计数和年龄标准化比率,以及不确定区间(UIs)。

全球范围内,2017年OA的年龄标准化点患病率和年发病率分别为每10万人口3754.2(95%UI 3389.4-4187.6)和181.2(95%UI 162.6-202.4),比1990年分别增加了9.3%(95%UI 8%-10.7%)和8.2%(95%UI 7.1%-9.4%)。此外,2017年全球年龄标准化的YLD率为118.8(95%UI 59.5-236.2),比1990年增加了9.6%(95%UI 8.3%-11.1%)。女性的全球患病率更高,并随着年龄而升高,2017年在男女> 95岁年龄组达到峰值。总体上,在地区和国家层面,年龄标准化YLD比率与SDI之间呈正相关。2017年, OA的年龄标准化患病率范围为每10万人口2090.3至6128.1例。美国(6128.1(95%UI 5729.3-6582.9))、美属萨摩亚(5281(95%UI 4688-5965.9))和科威特(5234.6(95%UI 4643.2-5953.6))的年龄标准化患病率最高。1990-2017年间,阿曼(29.6%(95%UI 24.8%-34.9%))、赤道几内亚(28.6%(95%UI 24.4%-33.7%)和美国(23.2%(95%UI 16.4%-30.5%))的年龄标准化患病率升高最多。

OA是一项重大的公共卫生挑战。尽管患病率、发病率和OA导致的YLDs存在明显的国际性差异,但大多数国家的负担正在增加。随着预期寿命的增加和全球人口的老龄化,预计这种情况将继续下去。建议提高人群和决策者对包括超重和伤害在内危险因素以及OA治疗重要性和益处的认识,并为越来越多的OA患者提供医疗服务,以管理这种疾病的未来负担。

原始出处:

Saeid Safiri. Global, regional and national burden of osteoarthritis 1990-2017: a systematic analysis of the Global Burden of Disease Study 2017. Ann Rheum Dis. 12 May 2020.

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    2020-08-27 lisa438
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    2020-05-15 thm112988

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