J Periodontal Res:牙周治疗或可短期内减缓牙周病患者颈动脉内膜增厚的进展

2022-08-26 MedSci原创 MedSci原创

牙周病是对口腔健康的一个主要威胁,如果不及时控制而任其发展,可能会引起其他全身性疾病。

牙周病是对口腔健康的一个主要威胁,如果不及时控制而任其发展,可能会引起其他全身性疾病。近日,发表于J Periodontal Res的一项系统回顾和荟萃分自旨在根据现有的流行病学和临床证据,评估牙周病、牙周治疗和颈动脉内中层厚度(CIMT)之间的关系。

研究人员检索了2021年5月之前PubMed和Scopus上收录的相关研究。观察性研究报告了牙周病(包括牙周炎和牙龈炎)与CIMT增加风险(定义为CIMT值超过临床和预后意义的临界值)之间的风险估计,以及提供牙周病干预前后CIMT的平均值和标准差的干预性研究,均被纳入。使用荟萃分析的随机效应模型来计算带有95%CIs的汇总效应估计值。

结果,研究人员从电子数据库中共检索出406条引文,筛选出45篇全文,剩下11篇使用超声测量CIMT的文章,共纳入8744名参与者。涉及8558名参与者的7项横断面研究的汇总结果表明,与没有牙周炎的人相比,牙周炎患者和严重牙周炎患者的CIMT增加的几率分别为1.42(95%CI:1.16,1.75)和1.70(95%CI:1.24,2.33)。尽管在这些文献结果存在出版物偏倚,校正后的几率仍然具有统计学意义。四项非随机对照试验的结果显示,186名患者在牙周干预治疗后短期内可能有助于减少其CIMT。

因此,该研究结果表明,牙周炎,尤其是严重的牙周炎,与CIMT风险的增加密切相关。牙周干预可能有助于在短期内减缓牙周病患者的颈动脉内膜增厚的进展。

 

原始出处:

Lifang Ding, et al., Meta-analysis of the association between periodontal disease, periodontal treatment and carotid intima-media thickness. J Periodontal Res. 2022 Aug;57(4):690-697. doi: 10.1111/jre.13006.  

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    2022-10-15 feather89
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    2022-08-26 小小医者

    #牙周炎#与患者#颈动脉内膜增厚#的关系,有意思

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