Lancet:心血管疾病风险、治疗、发病率及死亡率的性别差异研究

2020-05-21 MedSci原创 MedSci原创

女性接受心血管疾病一级预防的比例高于男性,而接受二级预防、心脏检查和冠状动脉血管重建的比例则较低,总体预后女性优于男性

来自高收入国家(HICS)的研究表明,女性接受心血管疾病护理(调查和治疗)的比例低于男性,导致更高的死亡风险。 然而,很少有研究系统地报告危险因素、初级或二级预防药物的使用、心血管疾病的发病率或社区死亡数据。 鉴于大多数心血管疾病发生在低收入和中等收入国家(LMICs),比较HICS和LMIC的男女患者的治疗和结果十分必要。
 
PURE研究中,来自27个国家的城市和农村地区的,年龄在35-70岁的志愿者参与,对202072名参与者的社会人口特征、危险因素、药物使用、心脏检查和干预措施信息进行考察。
 
2005-2019年间,总计202072名参与者接受调研,女性参与者的平均年龄为50.8岁,男性为51.7岁,平均随访9.5年。根据INTERHEART 和Framingham评估系统,女性的心血管疾病风险低于男性。女性采取初级预防措施(采取健康的生活方式行为和使用经证实的药物)的比例高于男性。每1000随访年中,女性心血管事件发生4.1起,男性为6.4起(HR=0.75),女性全因死亡4.5例,男性7.4例(0.62)。相反,女性接受二级预防措施、心脏检查和冠状动脉血管重建的比例低于男性。总体上,女性的复发性心血管疾病风险低于男性(20.0 vs 27.7起每1000随访年,HR=0.73)。在新发心血管事件的患者中,女性的30天死亡率低于男性(22% vs 28%)。相比于高收入国家,低收入国家男女接受治疗及结果的差异更为显著。
 
研究发现,女性接受心血管疾病一级预防的比例高于男性,而接受二级预防、心脏检查和冠状动脉血管重建的比例则较低。
 
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    2021-03-02 howi
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    2020-05-21 goodbing

    顶刊就是不一样,质量很高,内容精彩!学到很多

    0

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