Eur Heart J:道路交通噪音和心血管疾病危险因素的关系

2021-03-19 MedSci原创 MedSci原创

道路交通噪声>65dB [A]与血压和心血管生物化学指标发生微小但不利的变化有关,而与二氧化氮无关。

近日,血管领域权威杂志Eur Heart J上发表了一篇研究文章,这项研究旨在评估住宅道路交通噪声与心血管疾病危险因素[收缩压(SBP)和舒张压(DBP)、C反应蛋白、甘油三酯、糖化血红蛋白和自我报告的高血压]之间的横断面之间相关性。

研究人员于2006-2010年期间从英国生物库中招募了502651名40-69岁的受试者,并使用“通用噪声评估方法”模型的简化版本估算了研究地区2009年的道路交通噪声。研究人员使用了对年龄、性别、体重指数(BMI)、吸烟、饮酒、区域和个人剥夺、抽血季节、居住时间和二氧化氮进行调整的多元线性和逻辑回归模型进行分析。分析样本量超过了370000名参与者。

与≤55dB [A]相比,道路交通噪音>65dB [A]与SBP、DBP、甘油三酯和糖化血红蛋白分别升高0.77%[95%置信区间(CI)0.60%,0.95%]、0.49%(95%CI为0.32%,0.65%)、0.79%(95%CI为0.11%,1.47%)和0.12%(95%CI为0.04%,0.28%)相关。

噪音暴露与SBP或DBP之间的相关性似乎不受降压药物的影响,而在噪音暴露为60-65 dB[A]非药物治疗组中,其与自我报告的高血压之间呈正相关(比值比为1.07,95%CI为1.00,1.15)。

由此可见,道路交通噪声>65dB [A]与血压和心血管生物化学指标发生微小但不利的变化有关,而与二氧化氮无关

原始出处:

Zuzana Kupcikova,et al.Road traffic noise and cardiovascular disease risk factors in UK Biobank.European Heart Journal.2021.https://doi.org/10.1093/eurheartj/ehab121

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    2021-03-21 zhaojie88
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    2021-03-21 slcumt
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    2021-03-21 yuandd
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    2021-03-19 ms8000001132188048

    😇

    0

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