Allergy:产妇饮食与后代的过敏性疾病有关

2021-06-09 AlexYang MedSci原创

健康和疾病的发展起源假说表明,母亲在怀孕期间的暴露,包括营养摄入,可能对后代一生中的非传染性疾病风险有重大影响。最近,欧洲过敏和临床免疫学会(EAACI)通过元分析,回顾总结了调查怀孕期间食物模式和单

健康和疾病的发展起源假说表明,母亲在怀孕期间的暴露,包括营养摄入,可能对后代一生中的非传染性疾病风险有重大影响。最近,欧洲过敏和临床免疫学会(EAACI)通过元分析,回顾总结了调查怀孕期间食物模式和单一食物及营养素的摄入与后代过敏性鼻炎、特应性皮炎、哮喘、喘息和食物过敏发展之间关系的研究。该综述包括了饮食摄入的所有方面的研究。总的来说,结果显示只有一个显著的关联:母亲在怀孕期间补充维生素D后,后代的哮喘病会减少。

 

孕期饮食与后代过敏之间的联系有限。近期,有研究人员开发了一个孕期饮食指数,且与后代的过敏结果有关

研究数据来自Healthy Start。食物倾向调查问卷在怀孕期间完成。后代过敏性鼻炎、特应性皮炎、哮喘、喘息和4岁前的食物过敏诊断均由电子医疗记录核实。数据随机分为测试组和复制组。指数包括变量的加权组合,其对测试组中任何过敏都有最佳预测结果。研究人员还在复制组中验证了指数的效用。

指数包括了对蔬菜、酸奶、油炸土豆、大米/谷物、红肉、纯果汁和冷谷物摄入量的加权测量。研究结果发现,蔬菜和酸奶与任何过敏的预防有关,而其他成分则与疾病增加有关。在调整后的模型中,增加一个单位的指数与后代过敏性鼻炎(让步比(CI)0.82[0.72-0.94])、特应性皮炎(0.77[0.69-0.86])、哮喘(0.84[0.74-0.96])和喘息(0.80[0.71-0.90])的几率降低显著相关,但与食物过敏(0.84[0.66-1.08])无关。

产妇饮食指数与后代4岁前诊断为过敏性疾病几率的关系

综上所述,他们的研究首次显示了孕期母亲饮食摄入指数与后代多种过敏性疾病之间存在关联。这些结果对极早预防过敏性疾病带来了希望。

原始出处:

Carina Venter , Michaela P Palumbo , Deborah H Glueck et al. The Maternal Diet Index in Pregnancy is associated with offspring allergic diseases: The Healthy Start Study. Allergy. May 2021

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    2021-06-11 膀胱癌
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    2021-06-09 Ms20210609

    感谢分享 学习了

    0

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    2021-06-09 学习蜗牛

    学习了

    0

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