Acta Cir Bras:脱蛋白异种生物材料在吸入香烟烟雾的大鼠骨修复过程中的作用

2018-06-24 MedSci MedSci原创

本研究旨在探究无机牛骨基质是否会改变吸入香烟烟雾的大鼠的骨形成。 将20只Wistar大鼠分成两组:香烟组(CCG),在吸入室中吸入10支香烟,每天3次,10分钟,30天后由凝块填充骨缺损;卷烟生物材料组(CBG),相同的吸入技术,但骨缺损区填充生物材料。 结果显示,在CCG中,在分析的时间段(15和45天)中新骨组织存在明显差异,并且在15天、45天内分别形成了4.8±0.42和11.73±0.

本研究旨在探究无机牛骨基质是否会改变吸入香烟烟雾的大鼠的骨形成。

将20只Wistar大鼠分成两组:香烟组(CCG),在吸入室中吸入10支香烟,每天3次,10分钟,30天后由凝块填充骨缺损;卷烟生物材料组(CBG),相同的吸入技术,但骨缺损区填充生物材料。

结果显示,在CCG中,在分析的时间段(15和45天)中新骨组织存在明显差异,并且在15天、45天内分别形成了4.8±0.42和11.73±0.59骨(p <0.05)。CBG在15〜45天之间也有显著差异,分别为6.16±0.30和11.60±0.61。然而,当比较各组时,在相同的分析时段内,仅在15天期间观察到显著差异,CBG中的新骨比例较高。

综上所述,该研究结果表明,在骨再生的过程中,主要在初始阶段,骨基质作为骨诱导性生物材料,具有良好的生物相容性,可辅助骨再生。

原始出处:

Buchaim DV, Bueno PCDS, et al., Action of a deproteinized xenogenic biomaterial in the process of bone repair in rats submitted to inhalation of cigarette smoke. Acta Cir Bras. 2018 Apr;33(4):324-332. doi: 10.1590/s0102-865020180040000004.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (7)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2076923, encodeId=a08020e69231c, content=<a href='/topic/show?id=dc626935e20' target=_blank style='color:#2F92EE;'>#生物材#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69357, encryptionId=dc626935e20, topicName=生物材)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca282500032, createdName=1249857fm32暂无昵称, createdTime=Thu Jan 10 11:54:00 CST 2019, time=2019-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849605, encodeId=ede11849605a0, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Fri May 03 07:54:00 CST 2019, time=2019-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1719488, encodeId=10e41e1948811, content=<a href='/topic/show?id=17641015914f' target=_blank style='color:#2F92EE;'>#骨修复#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101591, encryptionId=17641015914f, topicName=骨修复)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a5232746261, createdName=axin020, createdTime=Wed Apr 10 21:54:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1372860, encodeId=43ff13e286061, content=<a href='/topic/show?id=63ff1014107e' target=_blank style='color:#2F92EE;'>#香烟#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101410, encryptionId=63ff1014107e, topicName=香烟)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9fe6351, createdName=flyingeagle77, createdTime=Tue Jun 26 11:54:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502991, encodeId=2600150299154, content=<a href='/topic/show?id=129069358ec' target=_blank style='color:#2F92EE;'>#生物材料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69358, encryptionId=129069358ec, topicName=生物材料)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=89399597484, createdName=dongjia2013, createdTime=Tue Jun 26 11:54:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326725, encodeId=10ae326e25f5, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Sun Jun 24 23:36:40 CST 2018, time=2018-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326694, encodeId=8007326694c8, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Jun 24 21:03:48 CST 2018, time=2018-06-24, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2076923, encodeId=a08020e69231c, content=<a href='/topic/show?id=dc626935e20' target=_blank style='color:#2F92EE;'>#生物材#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69357, encryptionId=dc626935e20, topicName=生物材)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca282500032, createdName=1249857fm32暂无昵称, createdTime=Thu Jan 10 11:54:00 CST 2019, time=2019-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849605, encodeId=ede11849605a0, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Fri May 03 07:54:00 CST 2019, time=2019-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1719488, encodeId=10e41e1948811, content=<a href='/topic/show?id=17641015914f' target=_blank style='color:#2F92EE;'>#骨修复#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101591, encryptionId=17641015914f, topicName=骨修复)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a5232746261, createdName=axin020, createdTime=Wed Apr 10 21:54:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1372860, encodeId=43ff13e286061, content=<a href='/topic/show?id=63ff1014107e' target=_blank style='color:#2F92EE;'>#香烟#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101410, encryptionId=63ff1014107e, topicName=香烟)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9fe6351, createdName=flyingeagle77, createdTime=Tue Jun 26 11:54:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502991, encodeId=2600150299154, content=<a href='/topic/show?id=129069358ec' target=_blank style='color:#2F92EE;'>#生物材料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69358, encryptionId=129069358ec, topicName=生物材料)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=89399597484, createdName=dongjia2013, createdTime=Tue Jun 26 11:54:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326725, encodeId=10ae326e25f5, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Sun Jun 24 23:36:40 CST 2018, time=2018-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326694, encodeId=8007326694c8, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Jun 24 21:03:48 CST 2018, time=2018-06-24, status=1, ipAttribution=)]
    2019-05-03 windight
  3. [GetPortalCommentsPageByObjectIdResponse(id=2076923, encodeId=a08020e69231c, content=<a href='/topic/show?id=dc626935e20' target=_blank style='color:#2F92EE;'>#生物材#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69357, encryptionId=dc626935e20, topicName=生物材)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca282500032, createdName=1249857fm32暂无昵称, createdTime=Thu Jan 10 11:54:00 CST 2019, time=2019-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849605, encodeId=ede11849605a0, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Fri May 03 07:54:00 CST 2019, time=2019-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1719488, encodeId=10e41e1948811, content=<a href='/topic/show?id=17641015914f' target=_blank style='color:#2F92EE;'>#骨修复#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101591, encryptionId=17641015914f, topicName=骨修复)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a5232746261, createdName=axin020, createdTime=Wed Apr 10 21:54:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1372860, encodeId=43ff13e286061, content=<a href='/topic/show?id=63ff1014107e' target=_blank style='color:#2F92EE;'>#香烟#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101410, encryptionId=63ff1014107e, topicName=香烟)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9fe6351, createdName=flyingeagle77, createdTime=Tue Jun 26 11:54:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502991, encodeId=2600150299154, content=<a href='/topic/show?id=129069358ec' target=_blank style='color:#2F92EE;'>#生物材料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69358, encryptionId=129069358ec, topicName=生物材料)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=89399597484, createdName=dongjia2013, createdTime=Tue Jun 26 11:54:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326725, encodeId=10ae326e25f5, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Sun Jun 24 23:36:40 CST 2018, time=2018-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326694, encodeId=8007326694c8, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Jun 24 21:03:48 CST 2018, time=2018-06-24, status=1, ipAttribution=)]
    2019-04-10 axin020
  4. [GetPortalCommentsPageByObjectIdResponse(id=2076923, encodeId=a08020e69231c, content=<a href='/topic/show?id=dc626935e20' target=_blank style='color:#2F92EE;'>#生物材#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69357, encryptionId=dc626935e20, topicName=生物材)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca282500032, createdName=1249857fm32暂无昵称, createdTime=Thu Jan 10 11:54:00 CST 2019, time=2019-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849605, encodeId=ede11849605a0, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Fri May 03 07:54:00 CST 2019, time=2019-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1719488, encodeId=10e41e1948811, content=<a href='/topic/show?id=17641015914f' target=_blank style='color:#2F92EE;'>#骨修复#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101591, encryptionId=17641015914f, topicName=骨修复)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a5232746261, createdName=axin020, createdTime=Wed Apr 10 21:54:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1372860, encodeId=43ff13e286061, content=<a href='/topic/show?id=63ff1014107e' target=_blank style='color:#2F92EE;'>#香烟#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101410, encryptionId=63ff1014107e, topicName=香烟)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9fe6351, createdName=flyingeagle77, createdTime=Tue Jun 26 11:54:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502991, encodeId=2600150299154, content=<a href='/topic/show?id=129069358ec' target=_blank style='color:#2F92EE;'>#生物材料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69358, encryptionId=129069358ec, topicName=生物材料)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=89399597484, createdName=dongjia2013, createdTime=Tue Jun 26 11:54:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326725, encodeId=10ae326e25f5, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Sun Jun 24 23:36:40 CST 2018, time=2018-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326694, encodeId=8007326694c8, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Jun 24 21:03:48 CST 2018, time=2018-06-24, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=2076923, encodeId=a08020e69231c, content=<a href='/topic/show?id=dc626935e20' target=_blank style='color:#2F92EE;'>#生物材#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69357, encryptionId=dc626935e20, topicName=生物材)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca282500032, createdName=1249857fm32暂无昵称, createdTime=Thu Jan 10 11:54:00 CST 2019, time=2019-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849605, encodeId=ede11849605a0, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Fri May 03 07:54:00 CST 2019, time=2019-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1719488, encodeId=10e41e1948811, content=<a href='/topic/show?id=17641015914f' target=_blank style='color:#2F92EE;'>#骨修复#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101591, encryptionId=17641015914f, topicName=骨修复)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a5232746261, createdName=axin020, createdTime=Wed Apr 10 21:54:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1372860, encodeId=43ff13e286061, content=<a href='/topic/show?id=63ff1014107e' target=_blank style='color:#2F92EE;'>#香烟#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101410, encryptionId=63ff1014107e, topicName=香烟)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9fe6351, createdName=flyingeagle77, createdTime=Tue Jun 26 11:54:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502991, encodeId=2600150299154, content=<a href='/topic/show?id=129069358ec' target=_blank style='color:#2F92EE;'>#生物材料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69358, encryptionId=129069358ec, topicName=生物材料)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=89399597484, createdName=dongjia2013, createdTime=Tue Jun 26 11:54:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326725, encodeId=10ae326e25f5, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Sun Jun 24 23:36:40 CST 2018, time=2018-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326694, encodeId=8007326694c8, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Jun 24 21:03:48 CST 2018, time=2018-06-24, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=2076923, encodeId=a08020e69231c, content=<a href='/topic/show?id=dc626935e20' target=_blank style='color:#2F92EE;'>#生物材#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69357, encryptionId=dc626935e20, topicName=生物材)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca282500032, createdName=1249857fm32暂无昵称, createdTime=Thu Jan 10 11:54:00 CST 2019, time=2019-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849605, encodeId=ede11849605a0, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Fri May 03 07:54:00 CST 2019, time=2019-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1719488, encodeId=10e41e1948811, content=<a href='/topic/show?id=17641015914f' target=_blank style='color:#2F92EE;'>#骨修复#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101591, encryptionId=17641015914f, topicName=骨修复)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a5232746261, createdName=axin020, createdTime=Wed Apr 10 21:54:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1372860, encodeId=43ff13e286061, content=<a href='/topic/show?id=63ff1014107e' target=_blank style='color:#2F92EE;'>#香烟#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101410, encryptionId=63ff1014107e, topicName=香烟)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9fe6351, createdName=flyingeagle77, createdTime=Tue Jun 26 11:54:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502991, encodeId=2600150299154, content=<a href='/topic/show?id=129069358ec' target=_blank style='color:#2F92EE;'>#生物材料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69358, encryptionId=129069358ec, topicName=生物材料)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=89399597484, createdName=dongjia2013, createdTime=Tue Jun 26 11:54:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326725, encodeId=10ae326e25f5, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Sun Jun 24 23:36:40 CST 2018, time=2018-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326694, encodeId=8007326694c8, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Jun 24 21:03:48 CST 2018, time=2018-06-24, status=1, ipAttribution=)]
    2018-06-24 1e1b8538m79(暂无匿称)

    不错的文章值得拥有哦

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2076923, encodeId=a08020e69231c, content=<a href='/topic/show?id=dc626935e20' target=_blank style='color:#2F92EE;'>#生物材#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69357, encryptionId=dc626935e20, topicName=生物材)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca282500032, createdName=1249857fm32暂无昵称, createdTime=Thu Jan 10 11:54:00 CST 2019, time=2019-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849605, encodeId=ede11849605a0, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Fri May 03 07:54:00 CST 2019, time=2019-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1719488, encodeId=10e41e1948811, content=<a href='/topic/show?id=17641015914f' target=_blank style='color:#2F92EE;'>#骨修复#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101591, encryptionId=17641015914f, topicName=骨修复)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a5232746261, createdName=axin020, createdTime=Wed Apr 10 21:54:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1372860, encodeId=43ff13e286061, content=<a href='/topic/show?id=63ff1014107e' target=_blank style='color:#2F92EE;'>#香烟#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101410, encryptionId=63ff1014107e, topicName=香烟)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9fe6351, createdName=flyingeagle77, createdTime=Tue Jun 26 11:54:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502991, encodeId=2600150299154, content=<a href='/topic/show?id=129069358ec' target=_blank style='color:#2F92EE;'>#生物材料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69358, encryptionId=129069358ec, topicName=生物材料)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=89399597484, createdName=dongjia2013, createdTime=Tue Jun 26 11:54:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326725, encodeId=10ae326e25f5, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Sun Jun 24 23:36:40 CST 2018, time=2018-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326694, encodeId=8007326694c8, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Jun 24 21:03:48 CST 2018, time=2018-06-24, status=1, ipAttribution=)]
    2018-06-24 天地飞扬

    了解一下.谢谢分享!

    0