Stroke:烟雾病儿童间接旁路术后长期疗效

2019-09-25 xing.T MedSci原创

由此可见,间接搭桥手术可以为烟雾病患儿的整体临床预后和长期卒中预防提供令人满意的长期改善。

在烟雾病患儿中,很少有关于外科手术预防卒中功效的研究报道。近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员在一个单中心评估了大量接受间接旁路手术的烟雾病患儿长期效果。

从1988年8月至2012年12月,有772名患儿接受了间接旁路手术。这项研究纳入了629例随访时间超过5年的患儿,其中不包括Moyamoya综合征患者。平均临床随访时间为12年(范围为5-29年)。根据Karnofsky绩效量表或Lansky Play绩效量表进行横断面分析,以评估总体临床结局和与不良结局相关的因素。为了分析手术的纵向效果,研究人员采用人年法计算间接旁路手术后手术半球出现症状性梗塞或出血的年度风险,并使用Kaplan-Meier方法评估无事件生存率。

95%的患者总体临床结局良好,手术半球的症状性梗塞和出血的年度风险分别为0.08%和0.04%。此外,有症状的梗塞和出血的10年无事件生存率分别为99.2%和99.8%。

由此可见,间接搭桥手术可以为烟雾病患儿的整体临床预后和长期卒中预防提供令人满意的长期改善。 

原始出处:

Eun Jin Ha.et al.Long-Term Outcomes of Indirect Bypass for 629 Children With Moyamoya Disease Longitudinal and Cross-Sectional Analysis.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.025609

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1241435, encodeId=e4591241435f1, content=<a href='/topic/show?id=f65b6e13468' target=_blank style='color:#2F92EE;'>#烟雾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67134, encryptionId=f65b6e13468, topicName=烟雾病)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=循证小兵, createdTime=Sun Aug 28 03:28:30 CST 2022, time=2022-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1815732, encodeId=60361815e32eb, content=<a href='/topic/show?id=79199e24877' target=_blank style='color:#2F92EE;'>#间接旁路术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97248, encryptionId=79199e24877, topicName=间接旁路术)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKCRibWHQArPHdSkqP90U1HwwqlGeU7BUgzY240D3v2ibBDJ09ybkGkwOjxz7qRmngZaGlK1taX6hfA/132, createdBy=2e772500094, createdName=小华子, createdTime=Sun Jan 26 01:47:00 CST 2020, time=2020-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1553502, encodeId=2dc8155350237, content=<a href='/topic/show?id=3b409e02804' target=_blank style='color:#2F92EE;'>#长期疗效#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97028, encryptionId=3b409e02804, topicName=长期疗效)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fe2a14383573, createdName=gjsgj, createdTime=Fri Sep 27 10:47:00 CST 2019, time=2019-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032292, encodeId=6fae103229263, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Wed Sep 25 22:47:00 CST 2019, time=2019-09-25, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1241435, encodeId=e4591241435f1, content=<a href='/topic/show?id=f65b6e13468' target=_blank style='color:#2F92EE;'>#烟雾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67134, encryptionId=f65b6e13468, topicName=烟雾病)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=循证小兵, createdTime=Sun Aug 28 03:28:30 CST 2022, time=2022-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1815732, encodeId=60361815e32eb, content=<a href='/topic/show?id=79199e24877' target=_blank style='color:#2F92EE;'>#间接旁路术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97248, encryptionId=79199e24877, topicName=间接旁路术)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKCRibWHQArPHdSkqP90U1HwwqlGeU7BUgzY240D3v2ibBDJ09ybkGkwOjxz7qRmngZaGlK1taX6hfA/132, createdBy=2e772500094, createdName=小华子, createdTime=Sun Jan 26 01:47:00 CST 2020, time=2020-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1553502, encodeId=2dc8155350237, content=<a href='/topic/show?id=3b409e02804' target=_blank style='color:#2F92EE;'>#长期疗效#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97028, encryptionId=3b409e02804, topicName=长期疗效)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fe2a14383573, createdName=gjsgj, createdTime=Fri Sep 27 10:47:00 CST 2019, time=2019-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032292, encodeId=6fae103229263, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Wed Sep 25 22:47:00 CST 2019, time=2019-09-25, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1241435, encodeId=e4591241435f1, content=<a href='/topic/show?id=f65b6e13468' target=_blank style='color:#2F92EE;'>#烟雾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67134, encryptionId=f65b6e13468, topicName=烟雾病)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=循证小兵, createdTime=Sun Aug 28 03:28:30 CST 2022, time=2022-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1815732, encodeId=60361815e32eb, content=<a href='/topic/show?id=79199e24877' target=_blank style='color:#2F92EE;'>#间接旁路术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97248, encryptionId=79199e24877, topicName=间接旁路术)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKCRibWHQArPHdSkqP90U1HwwqlGeU7BUgzY240D3v2ibBDJ09ybkGkwOjxz7qRmngZaGlK1taX6hfA/132, createdBy=2e772500094, createdName=小华子, createdTime=Sun Jan 26 01:47:00 CST 2020, time=2020-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1553502, encodeId=2dc8155350237, content=<a href='/topic/show?id=3b409e02804' target=_blank style='color:#2F92EE;'>#长期疗效#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97028, encryptionId=3b409e02804, topicName=长期疗效)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fe2a14383573, createdName=gjsgj, createdTime=Fri Sep 27 10:47:00 CST 2019, time=2019-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032292, encodeId=6fae103229263, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Wed Sep 25 22:47:00 CST 2019, time=2019-09-25, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1241435, encodeId=e4591241435f1, content=<a href='/topic/show?id=f65b6e13468' target=_blank style='color:#2F92EE;'>#烟雾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67134, encryptionId=f65b6e13468, topicName=烟雾病)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=循证小兵, createdTime=Sun Aug 28 03:28:30 CST 2022, time=2022-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1815732, encodeId=60361815e32eb, content=<a href='/topic/show?id=79199e24877' target=_blank style='color:#2F92EE;'>#间接旁路术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97248, encryptionId=79199e24877, topicName=间接旁路术)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKCRibWHQArPHdSkqP90U1HwwqlGeU7BUgzY240D3v2ibBDJ09ybkGkwOjxz7qRmngZaGlK1taX6hfA/132, createdBy=2e772500094, createdName=小华子, createdTime=Sun Jan 26 01:47:00 CST 2020, time=2020-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1553502, encodeId=2dc8155350237, content=<a href='/topic/show?id=3b409e02804' target=_blank style='color:#2F92EE;'>#长期疗效#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97028, encryptionId=3b409e02804, topicName=长期疗效)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fe2a14383573, createdName=gjsgj, createdTime=Fri Sep 27 10:47:00 CST 2019, time=2019-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032292, encodeId=6fae103229263, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Wed Sep 25 22:47:00 CST 2019, time=2019-09-25, status=1, ipAttribution=)]
    2019-09-25 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

相关资讯

Radiology:烟雾病患者做了血运重建术后脑灌注怎么样?

本研究旨在验证动脉自旋标记(ASL)磁共振(MR)成像在识别烟雾病患者血运重建术后脑血流量(CBF)、侧支循环流量和吻合口通畅度的能力,并将结果发表在Radiology上。

烟雾病伴蛛网膜下腔出血产妇行剖宫产术围手术期管理1例

产妇,28岁,身高160 cm,体重60kg,以“停经37+4周,头痛2周,加重1d”入院。8岁时曾发生脑梗死(脑梗),诊断为烟雾病,诊断过程不详,治疗后好转,10岁时再次发生脑梗,出现言语不清症状并遗留后遗症。

单侧烟雾病合并颅内多发动脉瘤1例

患者女性,56岁,因“突发头痛伴恶心、呕吐1d”急诊收住我院。病史:患者2018年1月11日早晨无明显诱因突发剧烈头痛,伴恶心、呕吐1次,为胃内容物。入院体检:嗜睡,双侧瞳孔等大等圆,直径约3mm,对光反射灵敏。颈软无抵抗,四肢肌力及肌张力正常,生理反射存在,病理反射未引出。急诊头颅CT示:右侧额颞叶脑出血,蛛网膜下腔出血(图1)。

Radiology:利用MR AccASL技术评估Moyamoya病其显示远端脑动脉及侧枝循环的的价值

目的:以DSA诊断作为金标,评估和比较AccASL-MRA和TOF-MRA两种成像方式在Moyamoya病中对脑动脉及侧枝循环显示的价值,并将结果发表在Radiology上。

迷雾样的烟雾病,似谜,似雾...

拨开“烟雾”,方见彩虹……