ATVB:妊娠和子痫前期与急性外周动脉事件有关

2020-10-18 MedSci原创 MedSci原创

在考虑到估计受孕时间和预后的局限性时,妊娠尤其是合并子痫前期会增加急性外周动脉事件的风险。

在妊娠期间的病例系列中,已报告了急性外周动脉事件,如主动脉夹层、颈动脉夹层、椎动脉夹层和动脉瘤破裂,但基于人群的数据很少。近日,血管领域权威杂志Arteriosclerosis, Thrombosis, and Vascular Biology上发表了一篇研究文章,这项研究旨在明确妊娠和子痫前期确是否为急性外周动脉事件的危险因素。

研究人员确定了多中心卫生保健系统中于1998年至2020年期间分娩的所有妇女。年龄小于18岁或大于50岁的妊娠分娩妇女被排除在外。该研究的主要结局是任何有症状或需要干预的急性外周动脉事件。研究人员使用Cox回归模型以时变协变量的方式评估血管事件与妊娠之间的关联。妊娠暴露期从估计的受孕日到产后3个月。

在176635名妇女中,有277697次妊娠(分娩率为81.3%,流产率为17.0%,异位妊娠率为1.7%),总随访时间为168万患者每年(中位数为7.9年;四分位间距为2.4-16.2)。子痫前期的孕妇占5.3%;在225763例分娩妇女中,有67790例(30.0%)孕妇是通过剖宫产分娩。随访期间发生了96例急性动脉事件,其中24例发生在妊娠期间,包括产后。妊娠(风险比为1.85 [95%CI为1.01–3.38];P=0.046)和子痫前期(风险比为10.9 [95%CI为5.24-22.7];P<0.001)是急性动脉事件的重要独立预测因子。

由此可见,在考虑到估计受孕时间和预后的局限性时,妊娠尤其是合并子痫前期会增加急性外周动脉事件的风险。

原始出处:

Charles DeCarlo.et al.Pregnancy and Preeclampsia Are Associated With Acute Adverse Peripheral Arterial Events.ATVB.2020.https://www.ahajournals.org/doi/10.1161/ATVBAHA.120.315174

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    2021-09-14 gongliu
  2. [GetPortalCommentsPageByObjectIdResponse(id=1977982, encodeId=8a8619e79820a, content=<a href='/topic/show?id=20411e958de' target=_blank style='color:#2F92EE;'>#TVB#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17958, encryptionId=20411e958de, topicName=TVB)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1a5a149, createdName=gongliu, createdTime=Tue Sep 14 04:47:54 CST 2021, time=2021-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=894777, encodeId=b044894e7702, content=在考虑到估计受孕时间和预后的局限性时,妊娠尤其是合并子痫前期会增加急性外周动脉事件的风险。, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae205385871, createdName=Lexi, createdTime=Tue Oct 27 10:55:51 CST 2020, time=2020-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893325, encodeId=c007893325aa, content=在考虑到估计受孕时间和预后的局限性时,妊娠尤其是合并子痫前期会增加急性外周动脉事件的风险。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Oct 20 16:56:15 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893236, encodeId=678a893236a3, content=学习,赚积分,很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/07/28/dc0a622c5c75f55fb8c848c04ece3cdc.jpg, createdBy=916d2333311, createdName=尹乔, createdTime=Tue Oct 20 09:07:05 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366576, encodeId=8f2b13665e67f, content=<a href='/topic/show?id=097a452219b' target=_blank style='color:#2F92EE;'>#子痫前期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45221, encryptionId=097a452219b, topicName=子痫前期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Tue Oct 20 05:47:54 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593339, encodeId=3d6d15933394b, content=<a href='/topic/show?id=8d1342e95fa' target=_blank style='color:#2F92EE;'>#外周动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42795, encryptionId=8d1342e95fa, topicName=外周动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b27818121614, createdName=wujh_7312825, createdTime=Tue Oct 20 05:47:54 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893115, encodeId=ac2189311561, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e8212476654, createdName=1244c0ebm28暂无昵称, createdTime=Mon Oct 19 18:25:12 CST 2020, time=2020-10-19, status=1, ipAttribution=)]
    2020-10-27 Lexi

    在考虑到估计受孕时间和预后的局限性时,妊娠尤其是合并子痫前期会增加急性外周动脉事件的风险。

    0

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    2020-10-20 咻凡

    在考虑到估计受孕时间和预后的局限性时,妊娠尤其是合并子痫前期会增加急性外周动脉事件的风险。

    0

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    2020-10-20 尹乔

    学习,赚积分,很有用

    0

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    2020-10-20 yahu
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  7. [GetPortalCommentsPageByObjectIdResponse(id=1977982, encodeId=8a8619e79820a, content=<a href='/topic/show?id=20411e958de' target=_blank style='color:#2F92EE;'>#TVB#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17958, encryptionId=20411e958de, topicName=TVB)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1a5a149, createdName=gongliu, createdTime=Tue Sep 14 04:47:54 CST 2021, time=2021-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=894777, encodeId=b044894e7702, content=在考虑到估计受孕时间和预后的局限性时,妊娠尤其是合并子痫前期会增加急性外周动脉事件的风险。, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae205385871, createdName=Lexi, createdTime=Tue Oct 27 10:55:51 CST 2020, time=2020-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893325, encodeId=c007893325aa, content=在考虑到估计受孕时间和预后的局限性时,妊娠尤其是合并子痫前期会增加急性外周动脉事件的风险。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Oct 20 16:56:15 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893236, encodeId=678a893236a3, content=学习,赚积分,很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/07/28/dc0a622c5c75f55fb8c848c04ece3cdc.jpg, createdBy=916d2333311, createdName=尹乔, createdTime=Tue Oct 20 09:07:05 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366576, encodeId=8f2b13665e67f, content=<a href='/topic/show?id=097a452219b' target=_blank style='color:#2F92EE;'>#子痫前期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45221, encryptionId=097a452219b, topicName=子痫前期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Tue Oct 20 05:47:54 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593339, encodeId=3d6d15933394b, content=<a href='/topic/show?id=8d1342e95fa' target=_blank style='color:#2F92EE;'>#外周动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42795, encryptionId=8d1342e95fa, topicName=外周动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b27818121614, createdName=wujh_7312825, createdTime=Tue Oct 20 05:47:54 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893115, encodeId=ac2189311561, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e8212476654, createdName=1244c0ebm28暂无昵称, createdTime=Mon Oct 19 18:25:12 CST 2020, time=2020-10-19, status=1, ipAttribution=)]
    2020-10-19 1244c0ebm28暂无昵称

    学习学习

    0

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