Hypertension:血压变异性与房颤发病率

2019-12-16 xing.T MedSci原创

由此可见,该研究的结果表明,较高的血压变异性与适度增加的房颤风险有关。

血压变异性是心血管疾病已知的危险因素,但其与房颤(AF)之间的关联尚未明确。近日,心血管权威杂志Hypertension上发表了一篇研究文章,研究人员旨在评估就诊期间血压变异性与房颤之间的关联。

这项基于人群的队列研究使用了健康筛查队列的数据库,该数据库包含一整套完整的医疗索赔数据和每两年一次人群健康检查信息。在排除已有房颤的受试者后,在2004年至2010年之间,研究者共收集了8063922名受试者,他们至少进行了3次血压检查。血压变异性定义为独立于平均值的变异性,分为四分位数。

在平均6.8年的随访期间,新诊断出140086名AF患者。最高的血压变异性(第四四分位数)与房颤风险增加相关(收缩压的风险比和95%CI为:1.06,1.05-1.08;舒张压为:1.07,1.05-1.08),相比于最低四分位数(第一个四分位数)。收缩压和舒张压变异性在第四个四分位范围内的受试者中,发生AF的风险比第一个四分位范围内的受试者高出7.6%。此外,无论是否患有高血压,该结果均一致。在亚组分析中,较高的血压变异性对房颤发展的影响在年龄较大(≥65岁)、患有糖尿病或慢性肾脏病的受试者中更为明显。

由此可见,该研究的结果表明,较高的血压变异性与适度增加的房颤风险有关。 

原始出处:

So-Ryoung Lee.et al.Blood Pressure Variability and Incidence of New-Onset Atrial Fibrillation A Nationwide Population-Based Study.Hypertension.2019.https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.119.13708

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    2020-07-11 feather89
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    2019-12-17 心介

    #血压变异性#相信未来5年是热点,不仅关心血压高与低,还要关注血压变异性才可以

    0

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    2019-12-17 心介

    房颤,临床上碰到很多哦

    0

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