Eur Heart J:房颤患者戒酒后卒中风险降低

2021-06-09 MedSci原创 MedSci原创

在新诊断的AF患者中,酒精摄入量与缺血性卒中风险增加相关,而在确诊AF后戒酒可以降低缺血性卒中的风险。应鼓励生活方式干预,包括注意饮酒,作为AF治疗综合方法的一部分,以改善临床结局。

近日,血管领域权威杂志Eur Heart J上发表了一篇研究文章,该研究旨在评估新诊断房颤(AF)后酒精摄入量(及其变化)与缺血性卒中风险之间的关系。

研究人员利用韩国全国的医疗声明和健康检查数据库,纳入了2010年至2016年间新诊断为AF的受试者。根据AF诊断前后的饮酒情况将患者分为三组:不饮酒组;确诊房颤后戒酒者和当前饮酒者。该研究的主要结局是随访期间发生的缺血性卒中。研究人员采用治疗加权反概率(IPTW)对不饮酒者、戒酒者和饮酒者的AF发病率差异进行了比较。

在总共97869名新诊断的AF患者中,51%为不饮酒的人,13%为戒酒者,36%为饮酒者。在310926人次-年的随访中,3120名患者被诊断为缺血性卒中(10.0/1000人-年)。

房颤患者戒酒后卒中风险

在5年的随访中,戒酒者和不饮酒者的卒中风险低于饮酒者(IPTW后,戒酒者和不饮酒者发病率差异分别为−2.03[−3.25,−0.82]和−2.98[−3.81,−2.15];IPTW后,不饮酒者和戒酒者的发病率比分别为0.75[0.70,0.81]和0.83[0.74,0.93]。

由此可见,在新诊断的AF患者中,酒精摄入量与缺血性卒中风险增加相关,而在确诊AF后戒酒可以降低缺血性卒中的风险。应鼓励生活方式干预,包括注意饮酒,作为AF治疗综合方法的一部分,以改善临床结局

原始出处:

So-Ryoung Lee.et al.Lower risk of stroke after alcohol abstinence in patients with incident atrial fibrillation: a nationwide population-based cohort study.European Heart Journal.2021.https://doi.org/10.1093/eurheartj/ehab315

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    2021-06-11 zhaojie88
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    2021-06-11 slcumt
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    2021-06-10 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2021-06-10 心介

    房颤,临床上碰到很多哦

    0

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    2021-06-10 guging

    中风是俗称,应该称为缺血性卒中吧

    0

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JAHA:房颤患者导管消融的相关并发症

该研究的数据显示,房颤患者CA术后并发症的发生率随年龄增长而增加。

JAMA:长期植入式心电图监测对新近缺血性中风患者房颤检出率的影响

对于新近发生缺血性中风但既往无房颤证据的患者,植入式心电图监测12个月相比于常规的30天外循环监测,房颤检出率显著提高,未来需要进一步的研究来考察长期植入式心电图监测的临床结果和成本效益。

Stroke:视网膜中央动脉阻塞后房颤的检出率

CRAO后AF的检出率高于年龄、性别和合并症匹配的对照者,与缺血性脑卒中后AF的检出率相当。阵发性AF应被认为是CRAO的一种病因,这些患者可能受益于长期的心脏监测。

JACC:非奈利酮可有效降低糖尿病合并慢性肾病患者的房颤发生率

在CKD合并T2D的患者中,非奈利酮治疗降低了新发AFF的风险,无论基线时有无AFF病史