Andrology :研究发现,吃核桃等坚果,能够改善精子质量,有益生育

2020-11-15 学术观察 iNature

当今社会,还有相当大的人群深受不孕不育的困扰,据统计,我国有超过5000万不育不孕患者,超过正常育龄人口的10%,这一数字远远超过了我们的想象,其中单纯男方因素占比约30%。

当今社会,还有相当大的人群深受不孕不育的困扰,据统计,我国有超过5000万不育不孕患者,超过正常育龄人口的10%,这一数字远远超过了我们的想象,其中单纯男方因素占比约30%,对于男性不育来说,精子质量问题是主要原因。

许多研究已经证实,环境和生活方式等因素都与精子质量下降有关,饮食也被发现能够影响精子质量,有一些研究发现了特定精子DNA甲基化标记的变化与精子质量之间的密切联系。但是,迄今为止还没有评估饮食对精子DNA功能变化影响的随机临床试验。

相信很多人都听过一种说法:吃核桃补脑。实际上,这种说法源自核桃仁很像大脑并无多少科学依据。然而,最近一项临床试验研究表明,食用核桃等坚果,能够改善精子质量,有益生育。

美国犹他大学医学院的研究人员在 Andrology 杂志发表了题为:Sperm DNA methylation changes after short‐term nut supplementation in healthy men consuming a Western‐style diet 的研究论文。

该研究首次评估了短期/中期食用混合坚果(杏仁,榛子和核桃)对西式饮食的健康个体的精子DNA甲基化的影响,研究结果表明,食用混合坚果14周可以显着改善精子数量、生存能力、运动能力和形态。

在这项临床试验研究中,研究团队招募了72名健康、不吸烟的年轻男性参与,其中48人食用坚果(每天食用60克),剩余24人作为对照组,研究人员观察到,在食用坚果组中,基线和试验结束之间36个基因组区域的甲基化差异显着,并且97.2%的区域显示出甲基化。

研究团队表示,这些发现提供了第一个证据,证实在常规西式饮食中添加坚果,会影响精子特定区域的DNA甲基化。更重要的是,食用混合坚果14周可以显着改善精子数量、生存能力、运动能力和形态。

论文第一作者 Albert Salas-Huetos 表示,这项工作表明,精子表观基因组中的某些敏感区域对饮食有反应,并可能导致精子表观遗传学的改变,进而影响精子质量及其受精能力。需要指出的是,该临床试验参与人数有限,食用坚果对精子质量改善等潜在健康健康益处还需要进一步研究,以验证在其他人群中的结果。

原始出处:

Albert Salas-Huetos, Emma R James, Jordi Salas-Salvadó, et al.Sperm DNA methylation changes after short-term nut supplementation in healthy men consuming a Western-style diet.Andrology. 2020 Sep 23. doi: 10.1111/andr.12911.

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    2021-05-21 Smile2680
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    2020-11-18 牧仔栋栋

    补肾填精

    0

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    2020-11-17 莉莉安 Lillian C.

    健康,不吸烟才是关键。

    0

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    2020-11-16 cscs

    补肾益精?

    0

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    2020-11-15 lovetcm

    #核桃##坚果#,能够改善#精子#质量,利于#生育#,男性朋友,你准备了么??

    0

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    2020-11-15 ms4000000798581120

    学习

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1753566, encodeId=15341e5356632, content=<a href='/topic/show?id=6a57e33772b' target=_blank style='color:#2F92EE;'>#研究发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73377, encryptionId=6a57e33772b, topicName=研究发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e1736602208, createdName=hanhaisha2020, createdTime=Tue Jul 13 12:08:55 CST 2021, time=2021-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1779896, encodeId=9ee11e798962b, content=<a href='/topic/show?id=28dc2499e8' target=_blank style='color:#2F92EE;'>#Androl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2499, encryptionId=28dc2499e8, topicName=Androl)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Fri May 21 21:08:55 CST 2021, time=2021-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=900093, encodeId=00ce90009310, content=补肾填精, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45435435877, createdName=牧仔栋栋, createdTime=Wed Nov 18 09:36:12 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899815, encodeId=a8858998154a, content=健康,不吸烟才是关键。, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200803/bf55cfcb09b74a0cbf751a980fe04576/e4480eaa47ab42da91303dd1c72e723e.jpg, createdBy=89fd5188713, createdName=莉莉安 Lillian C., createdTime=Tue Nov 17 11:02:22 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899430, encodeId=4972899430b9, content=补肾益精?, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201208/af76c3dece7248f2b297751d57470291/d45c15338e034c3f847da0bca70bfa4d.jpg, createdBy=3cfe1656094, createdName=cscs, createdTime=Mon Nov 16 01:37:02 CST 2020, time=2020-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899377, encodeId=9ffc8993e79e, content=<a href='/topic/show?id=3b6e62106e0' target=_blank style='color:#2F92EE;'>#核桃#</a>等<a href='/topic/show?id=d04f4148924' target=_blank style='color:#2F92EE;'>#坚果#</a>,能够改善<a href='/topic/show?id=5a22e6418b0' target=_blank style='color:#2F92EE;'>#精子#</a>质量,利于<a href='/topic/show?id=ded76955eec' target=_blank style='color:#2F92EE;'>#生育#</a>,男性朋友,你准备了么??, beContent=null, objectType=article, channel=null, level=null, likeNumber=166, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62106, encryptionId=3b6e62106e0, topicName=核桃), TopicDto(id=41489, encryptionId=d04f4148924, topicName=坚果), TopicDto(id=76418, encryptionId=5a22e6418b0, topicName=精子), TopicDto(id=69557, encryptionId=ded76955eec, topicName=生育)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Sun Nov 15 20:55:25 CST 2020, time=2020-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899347, encodeId=892589934ea8, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=71f65411944, createdName=ms4000000798581120, createdTime=Sun Nov 15 18:01:30 CST 2020, time=2020-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899340, encodeId=7e9c89934052, content=哈哈哈哈,核桃安排起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200930/e0fbd563d9054278997cb567f3351d90/db37f938d1ea4a96a7e324c062c9461b.jpg, createdBy=3d615392683, createdName=我是梁, createdTime=Sun Nov 15 17:12:14 CST 2020, time=2020-11-15, status=1, ipAttribution=)]
    2020-11-15 我是梁

    哈哈哈哈,核桃安排起来

    0

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