BMJ:英国儿童及青少年新冠肺炎患者特征

2020-08-30 MedSci原创 MedSci原创

儿童及青少年中重症新冠肺炎患者比例较低,但部分患儿会出现多系统炎症综合征症状,具有与一般患儿不同的人口学和临床特征

近日研究人员考察了英国经实验室证实的严重急性呼吸综合征冠状病毒2(SARS-Cov-2)感染住院的儿童和青少年患者的临床特征,并探讨与2019年冠状病毒疾病(COVID-19)相关的儿童和青少年入院危重护理、死亡率和多系统炎症综合征(MIS-C)风险因素。
 
 
研究人员收集了2020年1月17日至7月3日期间,英格兰、威尔士和苏格兰260家医院数据,期间651名19岁以下患者因新冠肺炎在138家医院接受治疗,研究的主要终点为危重护理率,住院死亡率和 MIS-C发病率。
 
患儿平均年龄4.6岁,其中35%(225例)为12个月以下患儿,男性患儿占56%,白种人占57%,南亚裔占12%,黑人占10%,42%的患儿(276例)存在其他共病。18%的患儿接受了重症护理(116例)。627名患儿中,6人(1%)院内死亡,均存在基础性共病。11%的患儿符合WHO-MIS-C定义,最早出现在3月中旬,多因素调整后,未满月婴儿(3.21)、10-14岁患儿(3.23)以及黑人患儿(2.82)出现MIS-C的风险较高,MIS-C患儿的重症监护风险是一般患儿的5倍(73% vs 15%),此外MIS-C患儿出现疲劳、头痛、肌痛、咽喉痛、淋巴结肿大及血小板计数小于150×109/L的风险显著增加,但MIS-C患儿中未出现死亡病例。
 
研究认为,儿童及青少年中重症新冠肺炎患者比例较低,但部分患儿会出现多系统炎症综合征症状,具有与一般患儿不同的人口学和临床特征。
 
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    2021-08-11 gaoxiaoe
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    2020-08-31 Jessica

    儿童及青少年中重症新冠肺炎患者比例较低,但部分患儿会出现多系统炎症综合征症状。

    0

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    2020-08-30 lovetcm

    儿童及青少年中重症#新冠肺炎#患者比例较低,但部分患儿会出现#多系统炎症综合征#症状,这是儿童与青少年的特征,后者事实上也相当危险

    0

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    2020-08-30 公卫新人

    新冠肺炎,疫情何时才能消失

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1849088, encodeId=f72d1849088c5, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Wed Aug 11 19:05:29 CST 2021, time=2021-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1623148, encodeId=313e1623148a5, content=<a href='/topic/show?id=e3935305e39' target=_blank style='color:#2F92EE;'>#患者特征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53057, encryptionId=e3935305e39, topicName=患者特征)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=450a20505925, createdName=guojianrong, createdTime=Tue Sep 01 02:05:29 CST 2020, time=2020-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=881460, encodeId=b70288146034, content=儿童及青少年中重症新冠肺炎患者比例较低,但部分患儿会出现多系统炎症综合征症状。, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Aug 31 18:14:02 CST 2020, time=2020-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=881026, encodeId=6ef188102635, content=儿童及青少年中重症<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a>患者比例较低,但部分患儿会出现<a href='/topic/show?id=cfae433e3a4' target=_blank style='color:#2F92EE;'>#多系统炎症综合征#</a>症状,这是儿童与青少年的特征,后者事实上也相当危险, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎), TopicDto(id=43373, encryptionId=cfae433e3a4, topicName=多系统炎症综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Sun Aug 30 19:34:11 CST 2020, time=2020-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028488, encodeId=0e0d102848813, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Aug 30 14:05:29 CST 2020, time=2020-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880864, encodeId=ca23880864d3, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200729/2ee0ca079ce64987b1195eb6aa20a1f4/ae923a98c9704879bacdc81d9fa7479a.jpg, createdBy=a3ab5398909, createdName=ms6000001113694287, createdTime=Sun Aug 30 13:41:35 CST 2020, time=2020-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880854, encodeId=bb8c880854d0, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=58615113870, createdName=1461f3b1m60暂无昵称, createdTime=Sun Aug 30 12:31:00 CST 2020, time=2020-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880842, encodeId=8f968808424a, content=值得参考, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b5e5414460, createdName=ms1000001370117417, createdTime=Sun Aug 30 11:40:28 CST 2020, time=2020-08-30, status=1, ipAttribution=)]
    2020-08-30 ms6000001113694287

    学习了

    0

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    2020-08-30 1461f3b1m60暂无昵称

    学习

    0

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    2020-08-30 ms1000001370117417

    值得参考

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