Clin Mol Allergy:呼吸道过敏性疾病患者的敏感性分析

2019-05-22 AlexYang MedSci原创

组分诊断(CRD)可以对单分子过敏原进行鉴定,是许多过敏诊断单位使用的常规方法。然而,皮刺试验(SPT)仍旧是许多耳鼻喉科门诊选择的方法,因此,增加了呼吸道过敏患者不充分免疫治疗的风险。最近,有研究人员在呼吸道过敏患者中比较了由SPT和CRD确诊的敏感性情况,并探索了敏感和类型和呼吸道疾病严重度之间的关系。研究包括了101名患者。SPT获得的敏感性情况与CRD获得的一致性较差,尤其是对于尘螨变应原

组分诊断(CRD)可以对单分子过敏原进行鉴定,是许多过敏诊断单位使用的常规方法。然而,皮刺试验(SPT)仍旧是许多耳鼻喉科门诊选择的方法,因此,增加了呼吸道过敏患者不充分免疫治疗的风险。最近,有研究人员在呼吸道过敏患者中比较了由SPT和CRD确诊的敏感性情况,并探索了敏感和类型和呼吸道疾病严重度之间的关系。

研究包括了101名患者。SPT获得的敏感性情况与CRD获得的一致性较差,尤其是对于尘螨变应原(噬皮螨属)和花粉(披针形植物、欧李属植物和常绿铜属植物) 。虽然SPT并没有表明敏感和呼吸道疾病类型/严重度之间的显著关系,但CRD表明了Der p 1、Der f 1和Lep d 2与哮喘之间的相关性,Der f 2和Lep d 2与更加严重过敏性鼻炎之间的相关性。

最后,研究人员指出,与SPT相比,CRD能够阐释出更加准确的敏感性情况,并鉴定出与症状和特异抗原之间的相关性。CRD在耳鼻喉科门诊中的常规使用也许对呼吸道过敏疾病患者有益。

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    2019-05-24 zhmscau
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    2019-05-24 膀胱癌
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最近,有研究人员鉴定了在过敏性鼻炎患者中,引起过敏症状的常见过敏原。研究是一个代表性的研究。包括了那些临床诊断为过敏性鼻炎的患者。研究人员对这些患者进行了皮刺试验(SPT),使用了12中常见的气源性过敏原。试验中包括了阳性对照和阴性对照,并记录了处理15分钟后的结果,并将水泡直径大于3毫米作为阳性反应。研究发现,在130名患者中,78(60%)名为男性,52(40%)名为女性。对任何一种过敏原敏感

Lancet:口服免疫疗法治疗花生过敏

研究认为,在花生过敏患者中,有高确定性证据表明,花生口服免疫治疗方案比避免过敏或安慰剂相比显著增加过敏和过敏反应风险

Asian Pac J Allergy Immunol:哮喘和/或过敏性鼻炎儿童中,大洪水和高空过敏症敏感性分析

洪水也许能够影响气源性致敏原敏化。最近,有研究人员在泰国曼谷2011年大洪水前后,通过皮刺试验(SPT),进行了旨在评估患有哮喘和/或者过敏性鼻炎(AR)儿童气源性致敏原敏化情况的研究。研究分别在2009年和2013年,共在2010名哮喘和/或AR的儿童中进行了SPT试验,结果的阳性率分别为58.2%和60.5%。气源性致敏原的多敏化作用在SPT阳性病人中的67.5%的哮喘病人和67.0%的AR病