Eur Arch Otorhinolaryngol:中性粒细胞与淋巴细胞比例在先天性突发感觉神经听力损失中的预后价值调查

2020-03-27 AlexYang MedSci原创

先天突发性感觉神经性听力损失(ISSNHL)的病因学、治疗和预后到目前仍旧不确定,尽管已经有了充分的调查。

先天突发性感觉神经性听力损失(ISSNHL)的病因学、治疗和预后到目前仍旧不确定,尽管已经有了充分的调查。

最近,有研究人员调查了中性粒细胞与淋巴细胞比例(NLR)与基于PSM的ISSNHL预后之间可能的关系。研究是一个回顾性的观察研究。研究人员来利用SPSS统计学程序(SPSS 19.0)对数据进行了统计学分析,并利用STATA(15.0)进行PSM。研究发现,NLR=3.42为截断值。PSM后,84对患者成功的进行匹配。有效组中NLR<3.42和NLR>3.42的患者数量显著不同(p<0.001)。

最后,研究人员指出,NLR是一个廉价的、可依赖的预测ISSNHIL的指数。研究人员认为NLR可以作为一个临床医生可依赖的因子来预测ISSNHL预后。为了进一步的证明NLR是ISSNHL中的一个有力的预后因子,未来还需要进一步的研究。

原始出处:

Wu S, Cao Z, Shi F et al. Investigation of the prognostic role of neutrophil-to-lymphocyte ratio in Idiopathic Sudden Sensorineural Hearing Loss based on propensity score matching: a retrospective observational study. Eur Arch Otorhinolaryngol. 13 Mar 2020

 

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    2020-03-29 ysjykql
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    2020-03-29 huirong
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PD-L2和PD-L1与食管癌患者的不良预后相关,这支持了PD-L2作为食管癌预后生物标志物的作用。