辉瑞公布LYRICA(普瑞巴林)治疗原发性全身强直-阵挛性癫痫发作的III期临床试验结果

2019-05-25 不详 网络

辉瑞公司近日宣布,一项旨在评估LYRICA(普瑞巴林)作为5~65岁癫痫患者辅助治疗原发性全身性强直-阵挛性癫痫发作(PGTC)的III期研究未达到其主要终点。

辉瑞公司近日宣布,一项旨在评估LYRICA(普瑞巴林)作为5~65癫痫患者辅助治疗原发性全身性强直-阵挛性癫痫发作(PGTC)的III期研究未达到其主要终点。与安慰剂相比,LYRICA的治疗没有导致癫痫发作率的统计学意义上的显著降低。

辉瑞公司研发和医疗全球首席医疗官Juan Ovalle博士说:这些数据有助于我们对癫痫疾病的理解,并反映出我们通过上市后研究推进医学研究的责任LYRICA(普瑞巴林)为γ-氨基丁酸(GABA)类似物,结构和作用与加巴喷丁相似,具有抗癫痫、镇痛和抗焦虑活性。


原始出处:

http://www.firstwordpharma.com/node/1643139#axzz5ovUpnHnX

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    2020-05-12 148c1818m61暂无昵称

    为什么要和安慰剂比,安慰剂有抗癫痫作用吗?

    0

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content=<a href='/topic/show?id=b317956200' target=_blank style='color:#2F92EE;'>#III期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9562, encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Mon May 27 09:07:00 CST 2019, time=2019-05-27, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=382744, encodeId=5710382e446e, content=为什么要和安慰剂比,安慰剂有抗癫痫作用吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=21635327744, createdName=148c1818m61暂无昵称, createdTime=Tue May 12 10:26:10 CST 2020, time=2020-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1652898, encodeId=be5d1652898ef, content=<a href='/topic/show?id=5b011018e07' target=_blank style='color:#2F92EE;'>#I期临床#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10187, encryptionId=5b011018e07, topicName=I期临床)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fc1f24335670, createdName=医生2402, createdTime=Thu Apr 02 09:07:00 CST 2020, time=2020-04-02, status=1, ipAttribution=), 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  6. [GetPortalCommentsPageByObjectIdResponse(id=382744, encodeId=5710382e446e, content=为什么要和安慰剂比,安慰剂有抗癫痫作用吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=21635327744, createdName=148c1818m61暂无昵称, createdTime=Tue May 12 10:26:10 CST 2020, time=2020-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1652898, encodeId=be5d1652898ef, content=<a href='/topic/show?id=5b011018e07' target=_blank style='color:#2F92EE;'>#I期临床#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10187, encryptionId=5b011018e07, topicName=I期临床)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fc1f24335670, createdName=医生2402, createdTime=Thu Apr 02 09:07:00 CST 2020, time=2020-04-02, status=1, ipAttribution=), 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encryptionId=c5a89550ff, topicName=III)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e68e415, createdName=juliusluan78, createdTime=Thu Nov 21 16:07:00 CST 2019, time=2019-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1310306, encodeId=35ad13103067a, content=<a href='/topic/show?id=24795994515' target=_blank style='color:#2F92EE;'>#普瑞巴林#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59945, encryptionId=24795994515, topicName=普瑞巴林)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Mon May 27 09:07:00 CST 2019, time=2019-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1524706, encodeId=471d1524e062b, content=<a href='/topic/show?id=4ba395994d' target=_blank style='color:#2F92EE;'>#II期临床#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9599, encryptionId=4ba395994d, topicName=II期临床)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=139811614978, createdName=guihongzh, createdTime=Mon May 27 09:07:00 CST 2019, time=2019-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588030, encodeId=ec4a1588030b1, content=<a href='/topic/show?id=056095e171' target=_blank style='color:#2F92EE;'>#III期临床试验#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9571, encryptionId=056095e171, topicName=III期临床试验)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d24217580122, createdName=guihongzh, createdTime=Mon May 27 09:07:00 CST 2019, time=2019-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1594597, encodeId=6604159459e2b, content=<a href='/topic/show?id=b317956200' target=_blank style='color:#2F92EE;'>#III期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9562, encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Mon May 27 09:07:00 CST 2019, time=2019-05-27, status=1, ipAttribution=)]
    2019-11-21 juliusluan78
  7. 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  8. 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  9. 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