Eur Heart J-Card Img:心房颤动消融成功相关的右心房功能和纤维化情况

2022-08-08 MedSci原创 MedSci原创

该研究表明RA重构参数不能预测AF消融后的复发。AF患者伴有双心房纤维化重构,且左心房纤维化程度与右心房纤维化程度有很强的相关性。

以心房结构和功能改变为特征的房性心律失常性重构在房颤(AF)的发生和维持中起着重要作用。此外,心房纤维化越来越被认为是导致房颤持续发生的重要因素。尽管最近的研究表明房颤常常伴有双侧心房的重构,但左心房重构过程受到了更加广泛的研究。

近日,心血管领域权威杂志Eur Heart J-Card Img上发表了一篇研究文章,研究人员旨在评估右心房与左心房纤维化的关系,以及右心房重构与房颤患者消融后房颤复发之间的可能关联。

该研究共纳入了110例接受初始肺静脉隔离(PVI)的房颤患者。所有患者在消融前进行的心脏磁共振(CMR)成像检查,且均为窦性心律。研究人员通过CMR图像来确定左心房和右心房体积和功能(体积和特征跟踪应变)。通过3D增强扫描评估左心房和右心房纤维化程度。研究人员采用12导联心电图或动态心电图随访了12个月时房颤复发情况。

在90天后,39例(36%)患者观察到心律失常复发,中位发生时间为181天(四分位差范围为122-286)。在消融后发生和未发生AF复发的患者中,右心房重构参数无显著差异,而左心房重构参数(体积、排空分数和应变指数)有所不同。左心房纤维化与右心房纤维化有很强的相关性(r=0.88,P<0.001)。左心房和右心房纤维化在伴有AF复发和不伴有AF复发患者之间无显著差异。

由此可见,该研究表明RA重构参数不能预测AF消融后的复发。AF患者伴有双心房纤维化重构,且左心房纤维化程度与右心房纤维化程度有很强的相关性。

原始出处:

Luuk H G A Hopman.et al.Right atrial function and fibrosis in relation to successful atrial fibrillation ablation.Eur Heart J-Card Img. 2022.https://academic.oup.com/ehjcimaging/advance-article/doi/10.1093/ehjci/jeac152/6654837

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    2023-03-24 wgsun
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    2023-02-01 ms3000001100640413 来自湖北省

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    2022-08-10 zhaojie88
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    2022-08-10 slcumt
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    2022-08-10 sodoo
  7. [GetPortalCommentsPageByObjectIdResponse(id=2023035, encodeId=c2b220230356d, content=<a href='/topic/show?id=68df38639cd' target=_blank style='color:#2F92EE;'>#右心房#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38639, encryptionId=68df38639cd, topicName=右心房)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=346311, createdName=wgsun, createdTime=Fri Mar 24 14:31:56 CST 2023, time=2023-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2112612, encodeId=7976211261263, content=多推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ec5c5432262, createdName=ms3000001100640413, createdTime=Wed Feb 01 19:09:57 CST 2023, time=2023-02-01, status=1, ipAttribution=湖北省), GetPortalCommentsPageByObjectIdResponse(id=1357960, encodeId=e854135e96084, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Aug 10 11:31:56 CST 2022, time=2022-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421906, encodeId=1130142190631, content=<a href='/topic/show?id=4bc865819d2' target=_blank style='color:#2F92EE;'>#消融#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65819, encryptionId=4bc865819d2, topicName=消融)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a193676008, createdName=xiangyuzhou972, createdTime=Wed Aug 10 11:31:56 CST 2022, time=2022-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563645, encodeId=06fc156364514, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Aug 10 11:31:56 CST 2022, time=2022-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626998, encodeId=9ecd1626998e3, content=<a href='/topic/show?id=986a5101e46' target=_blank style='color:#2F92EE;'>#心房#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51017, encryptionId=986a5101e46, topicName=心房)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=20ba21064884, createdName=sodoo, createdTime=Wed Aug 10 11:31:56 CST 2022, time=2022-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1237446, encodeId=24f5123e4465a, content=学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Mon Aug 08 22:33:25 CST 2022, time=2022-08-08, status=1, ipAttribution=)]
    2022-08-08 ms5000000518166734

    学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习

    0

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