Clin Nutrition:饮食不健康和久坐行为与癌症生存率有关。

2020-11-15 MedSci原创 MedSci原创

在美国,癌症是第二大最常见的慢性疾病和死亡原因。本项研究的目的是评估久坐行为和营养摄入量与美国癌症幸存者的总死亡率和特定于癌症的死亡率之间的关系。

背景与目标

在美国,癌症是第二大最常见的慢性疾病和死亡原因。本项研究的目的是评估久坐行为和营养摄入量与美国癌症幸存者的总死亡率和特定于癌症的死亡率之间的关系。

 

 

方法

1999年至2014年间,美国国家健康与营养检查调查收集了2371名癌症幸存者的数据,并将其与美国死亡率登记系统相关联。使用多变量调整的Cox比例风险模型估算与久坐时间和营养摄入量相关的全因和特定于癌症的死亡率的风险比(HR)和95%置信区间(CI)。

 

 

结果

在5.7年的中位数观察期内,癌症幸存者中共有532例死亡,其中180例是癌症特异性的。观察到久坐时间与全因死亡率之间呈递增线性关系(HR = 1.15,95%CI = 1.03,每增加一个标准差危险增加1.28)。膳食纤维,胡萝卜素,烟酸,硫胺素,核黄素,维生素B6,维生素B12和维生素C摄入量的最高三分位数与最低三分位数与全因和癌症特异性死亡率呈负相关(HRs = 0.48至0.75)。低久坐行为和高摄入量的膳食纤维,类胡萝卜素,维生素B12和维生素C的组合与全因死亡率的逆相关性更加明显。

 

 

结论

本项研究发现减少久坐的时间并遵循均衡饮食,并摄入足够的膳食纤维和微量营养可以大大改善癌症相关的死亡。

 

 

原始出处:

Cristian Ricci. Et al. Diet and sedentary behaviour in relation to cancer survival. A report from the national health and nutrition examination survey linked to the U.S. mortality registry.  Clinical Nutrition.2020.

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    2021-01-20 kun

    饮食重要

    0

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    2020-11-17 ms8000001754662727

    学习了

    0

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