Neurology:视神经脊髓炎的全球发生率和患病率

2020-12-14 MedSci原创 MedSci原创

NMOSD在全世界内是一种罕见的疾病。该分析已经描述了不同地理区域和种族之间患病率和发病率差异。这些只是通过不同的研究方法和NMO/NMOSD定义得到了部分解释。

自上次视神经脊髓炎/视神经脊髓炎谱系疾病(NMO/NMOSD)流行病学审查以来,又有22项相关研究发表。近日,神经病学领域权威杂志Neurology上发表了一篇研究文章,研究人员系统地回顾了NMOSD的全球患病率、发病率和基本人口统计学特征,并提供了重要的研究概述。

研究人员使用医学主题词和关键词以及检索到的文章的参考文献列表对PubMed、Ovid Medline和EMBASE数据库进行了检索,检索时间从1999年到2019年8月。研究人员收集了国家、地区、病例评估方法和水通道蛋白-4抗体(AQP4-Ab)检测、研究期间、限制、发病率(每10万人每年)、患病率(每100000人)、年龄、性别和种族特有的发病率或流行率数据。

研究人员确定了33条相关文章,结果表明,在非洲-加勒比地区,NMOSD的发病率和患病率最高[0.73/100000人每年(95%CI:0.45-1.01)和10/100000人(95%CI:6.8-13.2)] 。NMOSD的发生率和患病率在澳大利亚和新西兰最低[0.037/100000人每年(95%CI:0.036-0.038)和0.7/100000人(95%CI:0.66-0.74)]。在成年人和AQP4-Ab血清阳性亚群中,女性占主导地位。发病率和患病率在中年成年人中达到顶峰。非洲族裔的NMOSD发病率和患病率最高,而白人的患病率最低。随着时间的推移,没有发现明显的发病趋势。

由此可见,NMOSD在全世界内是一种罕见的疾病。该分析已经描述了不同地理区域和种族之间患病率和发病率差异。这些只是通过不同的研究方法和NMO/NMOSD定义得到了部分解释,突显了需要专门设计的流行病学研究来识别遗传效应和病因。

原始出处:

Viktoria Papp.et al.Worldwide incidence and prevalence of NMO: A systematic review.Neurology.2020.https://n.neurology.org/content/early/2020/12/11/WNL.0000000000011153

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    2021-10-20 gj0740
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createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Mon Dec 14 20:42:13 CST 2020, time=2020-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=907847, encodeId=1c5a90e84734, content=受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=72ca5431055, createdName=ms8000001392962515, createdTime=Mon Dec 14 15:43:01 CST 2020, time=2020-12-14, status=1, ipAttribution=)]
    2021-04-19 yinhl1978
  6. 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createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Mon Dec 14 20:42:13 CST 2020, time=2020-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=907847, encodeId=1c5a90e84734, content=受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=72ca5431055, createdName=ms8000001392962515, createdTime=Mon Dec 14 15:43:01 CST 2020, time=2020-12-14, status=1, ipAttribution=)]
    2021-01-11 yangchou

    罕见病的治疗和医保政策需要针对性。

    0

  7. 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  8. [GetPortalCommentsPageByObjectIdResponse(id=1826654, encodeId=7f3a18266546e, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Sun Jan 31 11:52:30 CST 2021, time=2021-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1650459, encodeId=ad4d1650459f8, content=<a href='/topic/show?id=b14384624a3' target=_blank style='color:#2F92EE;'>#脊髓炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84624, encryptionId=b14384624a3, topicName=脊髓炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=06db24008155, 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  9. [GetPortalCommentsPageByObjectIdResponse(id=1826654, encodeId=7f3a18266546e, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Sun Jan 31 11:52:30 CST 2021, time=2021-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1650459, encodeId=ad4d1650459f8, content=<a href='/topic/show?id=b14384624a3' target=_blank style='color:#2F92EE;'>#脊髓炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84624, encryptionId=b14384624a3, topicName=脊髓炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=06db24008155, 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href='/topic/show?id=abcd90e22c3' target=_blank style='color:#2F92EE;'>#视神经脊髓炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90722, encryptionId=abcd90e22c3, topicName=视神经脊髓炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4a587885671, createdName=ms8538335253054589, createdTime=Wed Dec 16 03:52:30 CST 2020, time=2020-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=907940, encodeId=f01d90e9400d, content=需要专门设计的流行病学研究来识别遗传效应和病因。<a href='/topic/show?id=5a8be955621' target=_blank style='color:#2F92EE;'>#罕见病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79556, encryptionId=5a8be955621, topicName=罕见病)], attachment=null, authenticateStatus=null, 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    2020-12-14 Baodongxu

    需要专门设计的流行病学研究来识别遗传效应和病因。#罕见病#

    0

  10. 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    2020-12-14 ms8000001392962515

    受益

    0

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近日发表的一项基于PURE研究全球20个国家的最新分析表明,在全球不同地区,年龄和性别标化的房颤患病率可相差12倍。研究发现,北美、欧洲、中国、东南亚最高(270-360例/10万).

JAHA:动脉-动脉栓塞性ST段抬高型心肌梗死的患病率、特征和预后

AAEMI是ST段抬高型心肌梗死的罕见原因,并具有独特的斑块形态特征,包括破裂部位较大的管腔面积,阻塞部位较小的管腔面积。

Sci Rep:公立医院工作人员颈肩痛的患病率及其相关因素

慢性NSP与医院级别、工作岗位、合同/临时工、工作量、人体工学因素(长期低头、长期扭头)和电脑相关因素显著相关。

JCEM:1型糖尿病患者非酒精性脂肪性肝病患病率

1型糖尿病患者NAFLD的患病率很高,并且高度依赖于所用的诊断方法和NAFLD定义。

Diabetes Care:美国2型糖尿病成人晚期肝纤维化患病率分析

T2DM患者肝脂肪变性和纤维化的患病率很高,肥胖是主要的危险因素。该研究的结果支持在糖尿病患者中筛查这一疾病。