Psychiatry Res:光疗可有效治疗非季节性抑郁症,当仍需更多的高质量证据证实

2021-04-10 MedSci原创 MedSci原创

既往研究已证实光疗在治疗季节性情感障碍方面的效果。然而,光疗在治疗非季节性抑郁症方面的效果仍不清楚。近日,来自人口健康与组织学重点实验室的研究人员进行了一项本荟萃分析,旨在确定光疗对非季节性抑郁症的疗

既往研究已证实光疗在治疗季节性情感障碍方面的效果。然而,光疗在治疗非季节性抑郁症方面的效果仍不清楚。近日,来自人口健康与组织学重点实验室的研究人员进行了一项本荟萃分析,旨在确定光疗对非季节性抑郁症的疗效,研究结果已发表于Psychiatry Res。

研究人员检索了PubMed、Web of Science、中国国家知识基础设施和中国生物医学文献库中截至2020年2月发表的随机对照试验(RCTs)。计算试验后抑郁评分的标准化平均差值及相应的95%置信区间,以评价光疗对非季节性抑郁症的疗效。

 

研究共纳入23个RCT,包括1120名参与者。荟萃分析结果显示,光疗的效果明显优于对比治疗。亚组分析显示,没有一个因素可以解释研究之间显著的异质性。

综上所述,该荟萃分析结果表明,光疗对减轻抑郁症状有轻中度治疗效果,可作为临床治疗非季节性抑郁症的一种治疗方法。但目前证据质量仍较低,需要更多设计良好、样本量较大、质量较高的研究来证实光疗治疗非季节性抑郁症的有效性。

 

原始出处:

 

Long Tao, et al., Light therapy in non-seasonal depression: An update meta-analysis. Psychiatry Res. 2020 Sep;291:113247. doi: 10.1016/j.psychres.2020.113247.

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    2021-12-18 俅侠
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    2021-04-12 30397606
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1747906, encodeId=8bb31e479061e, content=<a href='/topic/show?id=77d62883411' target=_blank style='color:#2F92EE;'>#光疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28834, encryptionId=77d62883411, topicName=光疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb1d35982112, createdName=俅侠, createdTime=Sat Dec 18 06:24:16 CST 2021, time=2021-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1792223, encodeId=e8931e9222358, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Wed Apr 28 05:24:16 CST 2021, time=2021-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1468738, encodeId=9ce11468e380c, content=<a href='/topic/show?id=a19b4540688' target=_blank style='color:#2F92EE;'>#季节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45406, encryptionId=a19b4540688, topicName=季节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cf986929326, createdName=30397606, createdTime=Mon Apr 12 07:24:16 CST 2021, time=2021-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1533437, encodeId=0889153343e4f, content=<a href='/topic/show?id=fe21454096b' target=_blank style='color:#2F92EE;'>#季节性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45409, encryptionId=fe21454096b, topicName=季节性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e4bd12435949, createdName=charleshjw, createdTime=Mon Apr 12 07:24:16 CST 2021, time=2021-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619598, encodeId=4bbe16195989f, content=<a href='/topic/show?id=8dd46061824' target=_blank style='color:#2F92EE;'>#有效治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60618, encryptionId=8dd46061824, topicName=有效治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Mon Apr 12 07:24:16 CST 2021, time=2021-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=955733, encodeId=733e955e33e9, content=刚百词斩看到一片英文的, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b1b55442837, createdName=ms3000001962617292, createdTime=Sat Apr 10 18:47:35 CST 2021, time=2021-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=955722, encodeId=ed58955e2247, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/qEBROvr2ZnB262ezVXrianiaZTlf6icjvajv2MKfmbb4HXMJ5cKiaey3yUy0Kf9wJdBAC1bkXjktDblroZT99ia7iagA/132, createdBy=32cb5279441, createdName=习惯keep, createdTime=Sat Apr 10 17:17:43 CST 2021, time=2021-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=955713, encodeId=f182955e1375, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=427d5479018, createdName=ms9000001550113929, createdTime=Sat Apr 10 16:35:32 CST 2021, time=2021-04-10, status=1, ipAttribution=)]
    2021-04-10 ms3000001962617292

    刚百词斩看到一片英文的

    0

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    2021-04-10 习惯keep

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1747906, encodeId=8bb31e479061e, content=<a href='/topic/show?id=77d62883411' target=_blank style='color:#2F92EE;'>#光疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28834, encryptionId=77d62883411, topicName=光疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb1d35982112, createdName=俅侠, createdTime=Sat Dec 18 06:24:16 CST 2021, time=2021-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1792223, encodeId=e8931e9222358, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Wed Apr 28 05:24:16 CST 2021, time=2021-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1468738, encodeId=9ce11468e380c, content=<a href='/topic/show?id=a19b4540688' target=_blank style='color:#2F92EE;'>#季节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45406, encryptionId=a19b4540688, topicName=季节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cf986929326, createdName=30397606, createdTime=Mon Apr 12 07:24:16 CST 2021, time=2021-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1533437, encodeId=0889153343e4f, content=<a href='/topic/show?id=fe21454096b' target=_blank style='color:#2F92EE;'>#季节性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45409, encryptionId=fe21454096b, topicName=季节性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e4bd12435949, createdName=charleshjw, createdTime=Mon Apr 12 07:24:16 CST 2021, time=2021-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619598, encodeId=4bbe16195989f, content=<a href='/topic/show?id=8dd46061824' target=_blank style='color:#2F92EE;'>#有效治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60618, encryptionId=8dd46061824, topicName=有效治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Mon Apr 12 07:24:16 CST 2021, time=2021-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=955733, encodeId=733e955e33e9, content=刚百词斩看到一片英文的, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b1b55442837, createdName=ms3000001962617292, createdTime=Sat Apr 10 18:47:35 CST 2021, time=2021-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=955722, encodeId=ed58955e2247, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/qEBROvr2ZnB262ezVXrianiaZTlf6icjvajv2MKfmbb4HXMJ5cKiaey3yUy0Kf9wJdBAC1bkXjktDblroZT99ia7iagA/132, createdBy=32cb5279441, createdName=习惯keep, createdTime=Sat Apr 10 17:17:43 CST 2021, time=2021-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=955713, encodeId=f182955e1375, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=427d5479018, createdName=ms9000001550113929, createdTime=Sat Apr 10 16:35:32 CST 2021, time=2021-04-10, status=1, ipAttribution=)]
    2021-04-10 ms9000001550113929

    0

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β 受体阻滞剂在心血管疾病的治疗中不可或缺,尤其是对射血分数降低型心衰、心律失常、心绞痛及高血压等。

Hypertension: β受体阻滞剂会引起抑郁吗?

这种对双盲随机对照试验大规模数据的分析并不支持β受体阻滞剂治疗与抑郁症之间的关联。

JAHA:肥厚性心肌病患者抑郁症与临床结局之间的关系

抑郁症在HCM患者中很常见。抑郁症的诊断与HCM患者SCD事件和心力衰竭事件的风险增加显著且独立相关。

有些人笑着却想自杀……抑郁症早期有4个征兆,快看看你符不符合

生活中,你是不是经常会发出这样的感慨?当你出现这样的心情时,你可能觉得自己是心情不好,过一段时间就好了,但你有可能患了抑郁症而不自知。

被高估的运动!JAMA:运动可能无助于改善认知

对于中年女性来说,运动对健康有很多好处,但它可能无助于长期维持认知功能。