Cancer Res :超25万人研究数据显示,口服避孕药可预防卵巢癌和子宫内膜癌

2020-12-20 MedSci原创 MedSci原创

卵巢癌和子宫内膜癌是最常见的三种妇科癌症,对女性健康有着非常大的危害。与卵巢癌相比,子宫内膜癌更为常见,由于其早期易发现,症状更明显,因此死亡率较低。然而,卵巢癌对女性来说是最致命的癌症之一,通常只有

卵巢癌和子宫内膜癌是最常见的三种妇科癌症,对女性健康有着非常大的危害。与卵巢癌相比,子宫内膜癌更为常见,由于其早期易发现,症状更明显,因此死亡率较低。然而,卵巢癌对女性来说是最致命的癌症之一,通常只有在卵巢癌扩散到其他部位后才被发现,是一种隐蔽性很强的癌症。近日,发表在Cancer Research杂志的一项研究显示,口服避孕药可预防卵巢癌和子宫内膜癌。停药后,保护效果依旧会持续数十年。

在该项研究中,研究人员通过对超过25万人的研究,调查了口服避孕药与乳腺癌、卵巢癌和子宫内膜癌之间的短期和长期的关系。研究收集了来自英国生物银行(UK Biobank)数据库出生自1939年至1970年的256,661名女性。研究人员收集了参与者的自我报告的数据(包括生活方式及病史等)和国家登记册中收集癌症诊断信息,直到20193月。通过使用LogisticCox回归分析评估了口服避孕药与癌症之间的发生风险。

结果发现,与从未使用人群相比,曾经使用口服避孕药女性患卵巢癌和子宫内膜癌的风险要低得多,而且使用时间越长,这种关联越强。在停用口服避孕药15年后,卵巢癌和子宫内膜癌风险降低了约50%即使在停药30-35年后,避孕药对卵巢癌和子宫内膜癌依旧具有保护作用。

不同随访年龄,口服避孕药与乳腺癌、卵巢癌、子宫内膜癌风险比

研究人员进一步发现,将随访年龄限制在55岁时,口服避孕药女性患乳腺癌的风险增加,但只是在短暂的时间内略有增加,在停用后几年这种风险就不存在了。也就是说,在整个时间段内,口服避孕药女性患乳腺癌风险并不明显。

因此,口服避孕药可以显著降低女性患卵巢癌和子宫内膜癌的风险,而其对乳腺癌终生风险的影响有限。研究表明,在停药后,口服避孕药对卵巢癌和子宫内膜癌的保护作用长达30-35。另外,口服避孕药的使用与患乳腺癌风险取决于时间和年龄。

原始出处

Karlsson T, Johansson T, Höglund T, Ek W, Johansson Å. (2020) Time-dependent effects of oral contraceptive use on breast, ovarian and endometrial cancers.Cancer Research (2020). 

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    2021-01-09 ms9000001986905864

    学习了

    0

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  4. [GetPortalCommentsPageByObjectIdResponse(id=1989249, encodeId=0d2d19892493f, content=<a href='/topic/show?id=496ce340173' target=_blank style='color:#2F92EE;'>#研究数据#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73401, encryptionId=496ce340173, topicName=研究数据)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8fc0211, createdName=doctor-chen9582, createdTime=Wed Feb 17 18:31:03 CST 2021, time=2021-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=914826, encodeId=beb591482652, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=022b5451308, createdName=ms9000001986905864, createdTime=Sat Jan 09 10:15:16 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1708615, encodeId=b1f51e08615b8, content=<a href='/topic/show?id=4c2d3051535' target=_blank style='color:#2F92EE;'>#内膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30515, encryptionId=4c2d3051535, topicName=内膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=730431558473, createdName=12498974m61暂无昵称, createdTime=Sat Jun 05 08:31:03 CST 2021, time=2021-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582162, encodeId=f7a8158216220, content=<a href='/topic/show?id=4fe43824210' target=_blank style='color:#2F92EE;'>#口服避孕药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38242, encryptionId=4fe43824210, topicName=口服避孕药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=da1416890157, createdName=654699882_84926991, createdTime=Tue Dec 22 09:31:03 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909917, encodeId=b76b90991e87, content=避孕药虽然叫避孕药 其本质只是性激素类药物 可以调节内分泌 并预防生殖器肿瘤, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200901/629d1ce7d6f64d17a642c37c90dea72c/202f9333a3ea4b23a9b07ede3364e86b.jpg, createdBy=1a335163906, createdName=Sunny orchard, createdTime=Mon Dec 21 23:10:45 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909709, encodeId=de43909e094e, content=不相信这个结果。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Dec 21 10:32:44 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909683, encodeId=de66909683fd, content=避孕药好处也有,副作用也有....希望有更多研究出现, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220301/6252e946e5ef413b86dc0f7d1f73b6db/9a7e8c88a38e487b8da4968a67bbd261.png, createdBy=b9f692910, createdName=rayms, createdTime=Mon Dec 21 08:32:07 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909665, encodeId=e497909665a5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bff55446245, createdName=ms9000001761297917, createdTime=Sun Dec 20 23:29:37 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909637, encodeId=eb2390963e28, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc854765440, createdName=1256062000, createdTime=Sun Dec 20 21:35:18 CST 2020, time=2020-12-20, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1989249, encodeId=0d2d19892493f, content=<a href='/topic/show?id=496ce340173' target=_blank style='color:#2F92EE;'>#研究数据#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73401, encryptionId=496ce340173, topicName=研究数据)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8fc0211, createdName=doctor-chen9582, createdTime=Wed Feb 17 18:31:03 CST 2021, time=2021-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=914826, encodeId=beb591482652, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=022b5451308, createdName=ms9000001986905864, createdTime=Sat Jan 09 10:15:16 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1708615, encodeId=b1f51e08615b8, content=<a href='/topic/show?id=4c2d3051535' target=_blank style='color:#2F92EE;'>#内膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30515, encryptionId=4c2d3051535, topicName=内膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=730431558473, createdName=12498974m61暂无昵称, createdTime=Sat Jun 05 08:31:03 CST 2021, time=2021-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582162, encodeId=f7a8158216220, content=<a href='/topic/show?id=4fe43824210' target=_blank style='color:#2F92EE;'>#口服避孕药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38242, encryptionId=4fe43824210, topicName=口服避孕药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=da1416890157, createdName=654699882_84926991, createdTime=Tue Dec 22 09:31:03 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909917, encodeId=b76b90991e87, content=避孕药虽然叫避孕药 其本质只是性激素类药物 可以调节内分泌 并预防生殖器肿瘤, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200901/629d1ce7d6f64d17a642c37c90dea72c/202f9333a3ea4b23a9b07ede3364e86b.jpg, createdBy=1a335163906, createdName=Sunny orchard, createdTime=Mon Dec 21 23:10:45 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909709, encodeId=de43909e094e, content=不相信这个结果。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Dec 21 10:32:44 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909683, encodeId=de66909683fd, content=避孕药好处也有,副作用也有....希望有更多研究出现, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220301/6252e946e5ef413b86dc0f7d1f73b6db/9a7e8c88a38e487b8da4968a67bbd261.png, createdBy=b9f692910, createdName=rayms, createdTime=Mon Dec 21 08:32:07 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909665, encodeId=e497909665a5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bff55446245, createdName=ms9000001761297917, createdTime=Sun Dec 20 23:29:37 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909637, encodeId=eb2390963e28, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc854765440, createdName=1256062000, createdTime=Sun Dec 20 21:35:18 CST 2020, time=2020-12-20, status=1, ipAttribution=)]
    2020-12-21 Sunny orchard

    避孕药虽然叫避孕药 其本质只是性激素类药物 可以调节内分泌 并预防生殖器肿瘤

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1989249, encodeId=0d2d19892493f, content=<a href='/topic/show?id=496ce340173' target=_blank style='color:#2F92EE;'>#研究数据#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73401, encryptionId=496ce340173, topicName=研究数据)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8fc0211, createdName=doctor-chen9582, createdTime=Wed Feb 17 18:31:03 CST 2021, time=2021-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=914826, encodeId=beb591482652, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=022b5451308, createdName=ms9000001986905864, createdTime=Sat Jan 09 10:15:16 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1708615, encodeId=b1f51e08615b8, content=<a href='/topic/show?id=4c2d3051535' target=_blank style='color:#2F92EE;'>#内膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30515, encryptionId=4c2d3051535, topicName=内膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=730431558473, createdName=12498974m61暂无昵称, createdTime=Sat Jun 05 08:31:03 CST 2021, time=2021-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582162, encodeId=f7a8158216220, content=<a href='/topic/show?id=4fe43824210' target=_blank style='color:#2F92EE;'>#口服避孕药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38242, encryptionId=4fe43824210, topicName=口服避孕药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=da1416890157, createdName=654699882_84926991, createdTime=Tue Dec 22 09:31:03 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909917, encodeId=b76b90991e87, content=避孕药虽然叫避孕药 其本质只是性激素类药物 可以调节内分泌 并预防生殖器肿瘤, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200901/629d1ce7d6f64d17a642c37c90dea72c/202f9333a3ea4b23a9b07ede3364e86b.jpg, createdBy=1a335163906, createdName=Sunny orchard, createdTime=Mon Dec 21 23:10:45 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909709, encodeId=de43909e094e, content=不相信这个结果。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Dec 21 10:32:44 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909683, encodeId=de66909683fd, content=避孕药好处也有,副作用也有....希望有更多研究出现, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220301/6252e946e5ef413b86dc0f7d1f73b6db/9a7e8c88a38e487b8da4968a67bbd261.png, createdBy=b9f692910, createdName=rayms, createdTime=Mon Dec 21 08:32:07 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909665, encodeId=e497909665a5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bff55446245, createdName=ms9000001761297917, createdTime=Sun Dec 20 23:29:37 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909637, encodeId=eb2390963e28, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc854765440, createdName=1256062000, createdTime=Sun Dec 20 21:35:18 CST 2020, time=2020-12-20, status=1, ipAttribution=)]
    2020-12-21 Jessica

    不相信这个结果。

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1989249, encodeId=0d2d19892493f, content=<a href='/topic/show?id=496ce340173' target=_blank style='color:#2F92EE;'>#研究数据#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73401, encryptionId=496ce340173, topicName=研究数据)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8fc0211, createdName=doctor-chen9582, createdTime=Wed Feb 17 18:31:03 CST 2021, time=2021-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=914826, encodeId=beb591482652, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=022b5451308, createdName=ms9000001986905864, createdTime=Sat Jan 09 10:15:16 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1708615, encodeId=b1f51e08615b8, content=<a href='/topic/show?id=4c2d3051535' target=_blank style='color:#2F92EE;'>#内膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30515, encryptionId=4c2d3051535, topicName=内膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=730431558473, createdName=12498974m61暂无昵称, createdTime=Sat Jun 05 08:31:03 CST 2021, time=2021-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582162, encodeId=f7a8158216220, content=<a href='/topic/show?id=4fe43824210' target=_blank style='color:#2F92EE;'>#口服避孕药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38242, encryptionId=4fe43824210, topicName=口服避孕药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=da1416890157, createdName=654699882_84926991, createdTime=Tue Dec 22 09:31:03 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909917, encodeId=b76b90991e87, content=避孕药虽然叫避孕药 其本质只是性激素类药物 可以调节内分泌 并预防生殖器肿瘤, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200901/629d1ce7d6f64d17a642c37c90dea72c/202f9333a3ea4b23a9b07ede3364e86b.jpg, createdBy=1a335163906, createdName=Sunny orchard, createdTime=Mon Dec 21 23:10:45 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909709, encodeId=de43909e094e, content=不相信这个结果。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Dec 21 10:32:44 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909683, encodeId=de66909683fd, content=避孕药好处也有,副作用也有....希望有更多研究出现, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220301/6252e946e5ef413b86dc0f7d1f73b6db/9a7e8c88a38e487b8da4968a67bbd261.png, createdBy=b9f692910, createdName=rayms, createdTime=Mon Dec 21 08:32:07 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909665, encodeId=e497909665a5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bff55446245, createdName=ms9000001761297917, createdTime=Sun Dec 20 23:29:37 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909637, encodeId=eb2390963e28, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc854765440, createdName=1256062000, createdTime=Sun Dec 20 21:35:18 CST 2020, time=2020-12-20, status=1, ipAttribution=)]
    2020-12-21 rayms

    避孕药好处也有,副作用也有....希望有更多研究出现

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1989249, encodeId=0d2d19892493f, content=<a href='/topic/show?id=496ce340173' target=_blank style='color:#2F92EE;'>#研究数据#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73401, encryptionId=496ce340173, topicName=研究数据)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8fc0211, createdName=doctor-chen9582, createdTime=Wed Feb 17 18:31:03 CST 2021, time=2021-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=914826, encodeId=beb591482652, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=022b5451308, createdName=ms9000001986905864, createdTime=Sat Jan 09 10:15:16 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1708615, encodeId=b1f51e08615b8, content=<a href='/topic/show?id=4c2d3051535' target=_blank style='color:#2F92EE;'>#内膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30515, encryptionId=4c2d3051535, topicName=内膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=730431558473, createdName=12498974m61暂无昵称, createdTime=Sat Jun 05 08:31:03 CST 2021, time=2021-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582162, encodeId=f7a8158216220, content=<a href='/topic/show?id=4fe43824210' target=_blank style='color:#2F92EE;'>#口服避孕药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38242, encryptionId=4fe43824210, topicName=口服避孕药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=da1416890157, createdName=654699882_84926991, createdTime=Tue Dec 22 09:31:03 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909917, encodeId=b76b90991e87, content=避孕药虽然叫避孕药 其本质只是性激素类药物 可以调节内分泌 并预防生殖器肿瘤, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200901/629d1ce7d6f64d17a642c37c90dea72c/202f9333a3ea4b23a9b07ede3364e86b.jpg, createdBy=1a335163906, createdName=Sunny orchard, createdTime=Mon Dec 21 23:10:45 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909709, encodeId=de43909e094e, content=不相信这个结果。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Dec 21 10:32:44 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909683, encodeId=de66909683fd, content=避孕药好处也有,副作用也有....希望有更多研究出现, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220301/6252e946e5ef413b86dc0f7d1f73b6db/9a7e8c88a38e487b8da4968a67bbd261.png, createdBy=b9f692910, createdName=rayms, createdTime=Mon Dec 21 08:32:07 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909665, encodeId=e497909665a5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bff55446245, createdName=ms9000001761297917, createdTime=Sun Dec 20 23:29:37 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909637, encodeId=eb2390963e28, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc854765440, createdName=1256062000, createdTime=Sun Dec 20 21:35:18 CST 2020, time=2020-12-20, status=1, ipAttribution=)]
    2020-12-20 ms9000001761297917

    学习

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1989249, encodeId=0d2d19892493f, content=<a href='/topic/show?id=496ce340173' target=_blank style='color:#2F92EE;'>#研究数据#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73401, encryptionId=496ce340173, topicName=研究数据)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8fc0211, createdName=doctor-chen9582, createdTime=Wed Feb 17 18:31:03 CST 2021, time=2021-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=914826, encodeId=beb591482652, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=022b5451308, createdName=ms9000001986905864, createdTime=Sat Jan 09 10:15:16 CST 2021, time=2021-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1708615, encodeId=b1f51e08615b8, content=<a href='/topic/show?id=4c2d3051535' target=_blank style='color:#2F92EE;'>#内膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30515, encryptionId=4c2d3051535, topicName=内膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=730431558473, createdName=12498974m61暂无昵称, createdTime=Sat Jun 05 08:31:03 CST 2021, time=2021-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582162, encodeId=f7a8158216220, content=<a href='/topic/show?id=4fe43824210' target=_blank style='color:#2F92EE;'>#口服避孕药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38242, encryptionId=4fe43824210, topicName=口服避孕药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=da1416890157, createdName=654699882_84926991, createdTime=Tue Dec 22 09:31:03 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909917, encodeId=b76b90991e87, content=避孕药虽然叫避孕药 其本质只是性激素类药物 可以调节内分泌 并预防生殖器肿瘤, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200901/629d1ce7d6f64d17a642c37c90dea72c/202f9333a3ea4b23a9b07ede3364e86b.jpg, createdBy=1a335163906, createdName=Sunny orchard, createdTime=Mon Dec 21 23:10:45 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909709, encodeId=de43909e094e, content=不相信这个结果。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Mon Dec 21 10:32:44 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909683, encodeId=de66909683fd, content=避孕药好处也有,副作用也有....希望有更多研究出现, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220301/6252e946e5ef413b86dc0f7d1f73b6db/9a7e8c88a38e487b8da4968a67bbd261.png, createdBy=b9f692910, createdName=rayms, createdTime=Mon Dec 21 08:32:07 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909665, encodeId=e497909665a5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bff55446245, createdName=ms9000001761297917, createdTime=Sun Dec 20 23:29:37 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909637, encodeId=eb2390963e28, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc854765440, createdName=1256062000, createdTime=Sun Dec 20 21:35:18 CST 2020, time=2020-12-20, status=1, ipAttribution=)]
    2020-12-20 1256062000

    学习

    0

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