Otolaryngol Head Neck Surg:鼻腔疾病的治疗对睡眠质量的影响:系统回顾和元分析

2021-07-24 AlexYang MedSci原创

鼻塞是耳鼻喉科实践中的最常见的症状之一,可由各种鼻科疾病引起。之前对鼻塞的两种常见病因的研究,即鼻炎和鼻中隔偏曲(NSD),阐述了它们在干扰睡眠方面的作用。这两种疾病会损害生活质量,它们可能通过结构和

鼻塞是耳鼻喉科实践中的最常见的症状之一,可由各种鼻科疾病引起。之前对鼻塞的两种常见病因的研究,即鼻炎和鼻中隔偏曲(NSD),阐述了它们在干扰睡眠方面的作用。这两种疾病会损害生活质量,它们可能通过结构和免疫学机制导致白天嗜睡、疲劳和认知能力下降。

近期,有研究人员确定了继发于过敏性鼻炎(AR)和鼻中隔偏移(NSD)的鼻腔阻塞患者的治疗对睡眠质量的影响

研究人员通过PubMed、Scopus、Cochrane图书馆和Web of Science筛查了主要研究。通过查询数据库,他们对2020年8月前发表的文章进行了系统回顾。纳入了报告客观睡眠参数(呼吸暂停-窒息指数)、鼻窦和睡眠特定患者报告的结果的测量:鼻结膜炎生活质量调查表、鼻腔阻塞症状评估、艾普沃斯睡眠量表(EpSS)和匹兹堡睡眠质量指数(PSQI)的研究。

数据库搜索产出了1414篇独特的文章,其中28个AR研究和7个NSD研究用于元分析。共确定了9037名患者(8515名AR患者,522名NSD患者),平均年龄为35.0岁(AR为35.3,NSD为34.0)。结果发现,对AR和NSD的治疗明显改善了主观睡眠质量。对于AR,EpSS的平均差异为-1.5(95% CI,-2.4至-0.5;P=0.002);对于PSQI,平均差异为-1.7(95%CI,-2.1至-1.2;P<0.00001)。对于NSD,EpSS的平均差异为-3.2(95%CI,-4.2至-2.2;P<0.00001),PSQI为-3.4(95%CI,-6.1至-0.6;P=0.02)。

NOSE评分、AHI、EpSS、PSQI和NSD的平均差情况

综上所述,AR和NSD在治疗后,主观睡眠质量得到了明显改善。但目前为止还没有足够的数据来证明睡眠质量的客观指标也有类似的改善

原始出处:

Jacob Fried , Erick Yuen , Kathy Zhang et al. Impact of Treatment for Nasal Cavity Disorders on Sleep Quality: Systematic Review and Meta-analysis. Otolaryngol Head Neck Surg. Jul 2021

 

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    2021-07-26 mnda
  5. [GetPortalCommentsPageByObjectIdResponse(id=1905863, encodeId=fefd190586304, content=<a href='/topic/show?id=8f2f28546b3' target=_blank style='color:#2F92EE;'>#元分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28546, encryptionId=8f2f28546b3, topicName=元分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b79433, createdName=jiangjun073, createdTime=Thu Mar 10 22:59:31 CST 2022, time=2022-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044196, encodeId=11cc2044196d4, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Tue Dec 21 07:59:31 CST 2021, time=2021-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1305769, encodeId=d5291305e6907, content=<a href='/topic/show?id=e87de303850' target=_blank style='color:#2F92EE;'>#睡眠质量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73038, encryptionId=e87de303850, topicName=睡眠质量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f612331, createdName=gds2009, createdTime=Mon Jul 26 02:59:31 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465893, encodeId=c12b146589399, content=<a href='/topic/show?id=736b103508c6' target=_blank style='color:#2F92EE;'>#鼻腔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103508, encryptionId=736b103508c6, topicName=鼻腔)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=224e6763385, createdName=mnda, createdTime=Mon Jul 26 02:59:31 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576428, encodeId=379c15e6428d1, content=<a href='/topic/show?id=e02ee6901a2' target=_blank style='color:#2F92EE;'>#系统回顾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76901, encryptionId=e02ee6901a2, topicName=系统回顾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27e316318097, createdName=ms5822920152752585, createdTime=Mon Jul 26 02:59:31 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002352, encodeId=d52f1002352ac, content=非常受用, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210724/725901dc0ed249ebba9d096aacddde3f/a89b874e17434adb82b0c2dff5f374f1.jpg, createdBy=c0225555986, createdName=@gxl, createdTime=Sat Jul 24 19:22:06 CST 2021, time=2021-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002205, encodeId=20bc100220520, content=懂了,, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e3a5478833, createdName=ms5000000790714074, createdTime=Sat Jul 24 12:56:27 CST 2021, time=2021-07-24, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1905863, encodeId=fefd190586304, content=<a href='/topic/show?id=8f2f28546b3' target=_blank style='color:#2F92EE;'>#元分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28546, encryptionId=8f2f28546b3, topicName=元分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b79433, createdName=jiangjun073, createdTime=Thu Mar 10 22:59:31 CST 2022, time=2022-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044196, encodeId=11cc2044196d4, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Tue Dec 21 07:59:31 CST 2021, time=2021-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1305769, encodeId=d5291305e6907, content=<a href='/topic/show?id=e87de303850' target=_blank style='color:#2F92EE;'>#睡眠质量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73038, encryptionId=e87de303850, topicName=睡眠质量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f612331, createdName=gds2009, createdTime=Mon Jul 26 02:59:31 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465893, encodeId=c12b146589399, content=<a href='/topic/show?id=736b103508c6' target=_blank style='color:#2F92EE;'>#鼻腔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103508, encryptionId=736b103508c6, topicName=鼻腔)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=224e6763385, createdName=mnda, createdTime=Mon Jul 26 02:59:31 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576428, encodeId=379c15e6428d1, content=<a href='/topic/show?id=e02ee6901a2' target=_blank style='color:#2F92EE;'>#系统回顾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76901, encryptionId=e02ee6901a2, topicName=系统回顾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27e316318097, createdName=ms5822920152752585, createdTime=Mon Jul 26 02:59:31 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002352, encodeId=d52f1002352ac, content=非常受用, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210724/725901dc0ed249ebba9d096aacddde3f/a89b874e17434adb82b0c2dff5f374f1.jpg, createdBy=c0225555986, createdName=@gxl, createdTime=Sat Jul 24 19:22:06 CST 2021, time=2021-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002205, encodeId=20bc100220520, content=懂了,, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e3a5478833, createdName=ms5000000790714074, createdTime=Sat Jul 24 12:56:27 CST 2021, time=2021-07-24, status=1, ipAttribution=)]
    2021-07-24 @gxl

    非常受用

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1905863, encodeId=fefd190586304, content=<a href='/topic/show?id=8f2f28546b3' target=_blank style='color:#2F92EE;'>#元分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28546, encryptionId=8f2f28546b3, topicName=元分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b79433, createdName=jiangjun073, createdTime=Thu Mar 10 22:59:31 CST 2022, time=2022-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044196, encodeId=11cc2044196d4, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Tue Dec 21 07:59:31 CST 2021, time=2021-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1305769, encodeId=d5291305e6907, content=<a href='/topic/show?id=e87de303850' target=_blank style='color:#2F92EE;'>#睡眠质量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73038, encryptionId=e87de303850, topicName=睡眠质量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f612331, createdName=gds2009, createdTime=Mon Jul 26 02:59:31 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465893, encodeId=c12b146589399, content=<a href='/topic/show?id=736b103508c6' target=_blank style='color:#2F92EE;'>#鼻腔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103508, encryptionId=736b103508c6, topicName=鼻腔)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=224e6763385, createdName=mnda, createdTime=Mon Jul 26 02:59:31 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576428, encodeId=379c15e6428d1, content=<a href='/topic/show?id=e02ee6901a2' target=_blank style='color:#2F92EE;'>#系统回顾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76901, encryptionId=e02ee6901a2, topicName=系统回顾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27e316318097, createdName=ms5822920152752585, createdTime=Mon Jul 26 02:59:31 CST 2021, time=2021-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002352, encodeId=d52f1002352ac, content=非常受用, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210724/725901dc0ed249ebba9d096aacddde3f/a89b874e17434adb82b0c2dff5f374f1.jpg, createdBy=c0225555986, createdName=@gxl, createdTime=Sat Jul 24 19:22:06 CST 2021, time=2021-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002205, encodeId=20bc100220520, content=懂了,, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e3a5478833, createdName=ms5000000790714074, createdTime=Sat Jul 24 12:56:27 CST 2021, time=2021-07-24, status=1, ipAttribution=)]
    2021-07-24 ms5000000790714074

    懂了,

    0

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