Int J Cardiol:气候变化与ST段抬高心肌梗死患者经皮冠状动脉成形术治疗的关系

2019-07-04 xing.T MedSci原创

由此可见,气候对当前PPCI风险产生了重大影响,并且根据季节存在复杂的相互作用。预计前几天最低气压降低,冬季降雨量降低,春季大气压力变化较大,夏季气温升高,PPCI风险较高。这些发现对预防策略具有重要意义。

季节性变化对急性心肌梗死发生率的影响尚未得到充分评估,特别是在经皮冠状动脉介入治疗(PPCI)充分发展的时期。近日,心血管领域权威杂志International Journal of Cardiology上发表了一篇研究文章,研究人员的目的是评估气候变化对PCCI每日发生率的总体和季节性影响。

三个具有不同地理特征的意大利大型机构回顾性地收集了PPCI和气候变化的详细信息。研究人员利用泊松模型评估PPCI的发生率与温度、大气压(ATM)、湿度和降雨量之间的关联,并根据一年中的季节进行评估和总体分析。

研究人员收集了6880天的详细信息,共计4132例PPCI。总体调整分析显示,PPCI前3天较高的最低气压与较低的风险相关(回归系数=0.999 [95%置信区间为0.998-1.000],p=0.030)。对于季节,在冬季,PPCI的发生率在较低的平均温度(0.973 [0.956-0.990],p=0.002)和较低降雨量(0.980 [0.960-1.000],p=0.049)当天有所增加。相反,在春季,PPCI前3天大气压力的变化与风险增加有关(1.023 [1.002-1.045],p=0.032),同一天夏季最低气温的影响相似(1.022 [1.001-1.044]] ,p=0.040)。

由此可见,气候对当前PPCI风险产生了重大影响,并且根据季节存在复杂的相互作用。预计前几天最低气压降低,冬季降雨量降低,春季大气压力变化较大,夏季气温升高,PPCI风险较高。这些发现对预防策略具有重要意义。 

原始出处:

FrancescoVersaci,et al.Climate changes and ST-elevation myocardial infarction treated with primary percutaneous coronary angioplasty.International Journal of Cardiology.2019.https://www.sciencedirect.com/science/article/pii/S0167527319313051

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    2019-07-06 gdsun
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    2019-07-06 hyf035

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