AJG: 巴雷特(Barrett's)食管治疗后的监测最有利于预防重度不典型增生或黏膜内癌的发生

2022-07-03 xuyihan MedSci原创

射频消融是通过股动静脉、颈内静脉、锁骨下静脉的途径,把电极导管插入心脏,用电生理标测技术找到心脏内异常电传导通道或异位搏动点,利用大头导管顶端的电极在心肌组织内产生阻力性电热效应。

射频消融 (RFA) 是一种安全有效的治疗发育不良的巴雷特食管 (BE)的医学手段。但是完全根除肠化生 (CEIM) 后,BE的复发很常见,每年有8%–10%的接受治疗的患者会进展为发育不良或癌症。为保护患者免于疾病的复发形成,指南建议对任何复发性肠化生和瘤形成患者进行再治疗的监测内镜检查。尽管内镜根除治疗后的监测结果在观察性研究中始终良好,但没有研究对此进行证实,为此,本项研究比较了低度不典型增生 (LGD) 治疗后监测与高度不典型增生 (HGD) 或黏膜内腺癌治疗后监测的效果。

美国RFA登记数据库是一个由148 家机构(113 家社区和 35 家学术附属机构)中接受 RFA 治疗的巴雷特食管患者组成的数据库。研究人员首先使用拟合模型来估算任何复发或再治疗后复发和肿瘤进展的自然史,然后将消融治疗后侵袭性腺癌的自然史估计值与 5 年时的治疗估计值进行比较,以得出内镜监测的预防风险的效果。

研究结果显示在接受CEIM治疗后高度不典型增生 (HGD) 或黏膜内腺癌消融后进展为浸润性腺癌的自然史估计在5年为6.3%,而低度不典型增生 (LGD) 为1.3%。自然史模型发现,与 LGD (-1.1%) 相比,监测 HGD/黏膜内腺癌 (-4.8%) 的预防风险差异要高得多。这些组在 5 年时需要监测的人数分别为 21 和 90,以预防 1 例浸润性食管腺癌,使基线 HGD 成功消融后的监测预防浸润性癌的效果是成功消融后的4倍以上。

本项研究证实成功消融基线HGD或粘膜内癌后的内镜监测比成功治疗基线 LGD 后的监测在避免浸润性腺癌方面更有效。虽然监测治疗 LGD 的适度益处可能大于内镜检查不良反应平均风险患者的风险,但临床医生应专注于将基线 HGD 或癌症患者保留在内镜监测计划中。

 

原始出处:

Cotton, Cary C.et al. Surveillance After Treatment of Barrett's Esophagus Benefits Those With High-Grade Dysplasia or Intramucosal Cancer Most. The American Journal of Gastroenterology.2022.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (7)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1913964, encodeId=528d1913964ea, content=<a href='/topic/show?id=4684153e41f' target=_blank style='color:#2F92EE;'>#RET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15374, encryptionId=4684153e41f, topicName=RET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Tue Aug 16 18:43:22 CST 2022, time=2022-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057358, encodeId=f4bd205e35824, content=<a href='/topic/show?id=18982222db' target=_blank style='color:#2F92EE;'>#AJG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2222, encryptionId=18982222db, topicName=AJG)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2978132, createdName=minzju5052, createdTime=Mon Oct 24 14:43:22 CST 2022, time=2022-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970316, encodeId=617b19e0316fe, content=<a href='/topic/show?id=bc8d202929a' target=_blank style='color:#2F92EE;'>#不典型增生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20292, encryptionId=bc8d202929a, topicName=不典型增生)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5d70341, createdName=zhishijing, createdTime=Sat Feb 04 20:43:22 CST 2023, time=2023-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1898669, encodeId=6e7d1898669a4, content=<a href='/topic/show?id=e5062028978' target=_blank style='color:#2F92EE;'>#不典型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20289, encryptionId=e5062028978, topicName=不典型)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Mon Mar 20 23:43:22 CST 2023, time=2023-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437754, encodeId=184c143e7542c, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520109, encodeId=45491520109a2, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624634, encodeId=fbe116246346f, content=<a href='/topic/show?id=e52b3206cb' target=_blank style='color:#2F92EE;'>#Barrett#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3206, encryptionId=e52b3206cb, topicName=Barrett)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e94c20680600, createdName=yangeasy, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1913964, encodeId=528d1913964ea, content=<a href='/topic/show?id=4684153e41f' target=_blank style='color:#2F92EE;'>#RET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15374, encryptionId=4684153e41f, topicName=RET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Tue Aug 16 18:43:22 CST 2022, time=2022-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057358, encodeId=f4bd205e35824, content=<a href='/topic/show?id=18982222db' target=_blank style='color:#2F92EE;'>#AJG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2222, encryptionId=18982222db, topicName=AJG)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2978132, createdName=minzju5052, createdTime=Mon Oct 24 14:43:22 CST 2022, time=2022-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970316, encodeId=617b19e0316fe, content=<a href='/topic/show?id=bc8d202929a' target=_blank style='color:#2F92EE;'>#不典型增生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20292, encryptionId=bc8d202929a, topicName=不典型增生)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5d70341, createdName=zhishijing, createdTime=Sat Feb 04 20:43:22 CST 2023, time=2023-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1898669, encodeId=6e7d1898669a4, content=<a href='/topic/show?id=e5062028978' target=_blank style='color:#2F92EE;'>#不典型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20289, encryptionId=e5062028978, topicName=不典型)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Mon Mar 20 23:43:22 CST 2023, time=2023-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437754, encodeId=184c143e7542c, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520109, encodeId=45491520109a2, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624634, encodeId=fbe116246346f, content=<a href='/topic/show?id=e52b3206cb' target=_blank style='color:#2F92EE;'>#Barrett#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3206, encryptionId=e52b3206cb, topicName=Barrett)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e94c20680600, createdName=yangeasy, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=)]
    2022-10-24 minzju5052
  3. [GetPortalCommentsPageByObjectIdResponse(id=1913964, encodeId=528d1913964ea, content=<a href='/topic/show?id=4684153e41f' target=_blank style='color:#2F92EE;'>#RET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15374, encryptionId=4684153e41f, topicName=RET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Tue Aug 16 18:43:22 CST 2022, time=2022-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057358, encodeId=f4bd205e35824, content=<a href='/topic/show?id=18982222db' target=_blank style='color:#2F92EE;'>#AJG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2222, encryptionId=18982222db, topicName=AJG)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2978132, createdName=minzju5052, createdTime=Mon Oct 24 14:43:22 CST 2022, time=2022-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970316, encodeId=617b19e0316fe, content=<a href='/topic/show?id=bc8d202929a' target=_blank style='color:#2F92EE;'>#不典型增生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20292, encryptionId=bc8d202929a, topicName=不典型增生)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5d70341, createdName=zhishijing, createdTime=Sat Feb 04 20:43:22 CST 2023, time=2023-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1898669, encodeId=6e7d1898669a4, content=<a href='/topic/show?id=e5062028978' target=_blank style='color:#2F92EE;'>#不典型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20289, encryptionId=e5062028978, topicName=不典型)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Mon Mar 20 23:43:22 CST 2023, time=2023-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437754, encodeId=184c143e7542c, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520109, encodeId=45491520109a2, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624634, encodeId=fbe116246346f, content=<a href='/topic/show?id=e52b3206cb' target=_blank style='color:#2F92EE;'>#Barrett#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3206, encryptionId=e52b3206cb, topicName=Barrett)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e94c20680600, createdName=yangeasy, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1913964, encodeId=528d1913964ea, content=<a href='/topic/show?id=4684153e41f' target=_blank style='color:#2F92EE;'>#RET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15374, encryptionId=4684153e41f, topicName=RET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Tue Aug 16 18:43:22 CST 2022, time=2022-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057358, encodeId=f4bd205e35824, content=<a href='/topic/show?id=18982222db' target=_blank style='color:#2F92EE;'>#AJG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2222, encryptionId=18982222db, topicName=AJG)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2978132, createdName=minzju5052, createdTime=Mon Oct 24 14:43:22 CST 2022, time=2022-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970316, encodeId=617b19e0316fe, content=<a href='/topic/show?id=bc8d202929a' target=_blank style='color:#2F92EE;'>#不典型增生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20292, encryptionId=bc8d202929a, topicName=不典型增生)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5d70341, createdName=zhishijing, createdTime=Sat Feb 04 20:43:22 CST 2023, time=2023-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1898669, encodeId=6e7d1898669a4, content=<a href='/topic/show?id=e5062028978' target=_blank style='color:#2F92EE;'>#不典型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20289, encryptionId=e5062028978, topicName=不典型)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Mon Mar 20 23:43:22 CST 2023, time=2023-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437754, encodeId=184c143e7542c, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520109, encodeId=45491520109a2, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624634, encodeId=fbe116246346f, content=<a href='/topic/show?id=e52b3206cb' target=_blank style='color:#2F92EE;'>#Barrett#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3206, encryptionId=e52b3206cb, topicName=Barrett)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e94c20680600, createdName=yangeasy, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=)]
    2023-03-20 yaanren
  5. [GetPortalCommentsPageByObjectIdResponse(id=1913964, encodeId=528d1913964ea, content=<a href='/topic/show?id=4684153e41f' target=_blank style='color:#2F92EE;'>#RET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15374, encryptionId=4684153e41f, topicName=RET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Tue Aug 16 18:43:22 CST 2022, time=2022-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057358, encodeId=f4bd205e35824, content=<a href='/topic/show?id=18982222db' target=_blank style='color:#2F92EE;'>#AJG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2222, encryptionId=18982222db, topicName=AJG)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2978132, createdName=minzju5052, createdTime=Mon Oct 24 14:43:22 CST 2022, time=2022-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970316, encodeId=617b19e0316fe, content=<a href='/topic/show?id=bc8d202929a' target=_blank style='color:#2F92EE;'>#不典型增生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20292, encryptionId=bc8d202929a, topicName=不典型增生)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5d70341, createdName=zhishijing, createdTime=Sat Feb 04 20:43:22 CST 2023, time=2023-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1898669, encodeId=6e7d1898669a4, content=<a href='/topic/show?id=e5062028978' target=_blank style='color:#2F92EE;'>#不典型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20289, encryptionId=e5062028978, topicName=不典型)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Mon Mar 20 23:43:22 CST 2023, time=2023-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437754, encodeId=184c143e7542c, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520109, encodeId=45491520109a2, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624634, encodeId=fbe116246346f, content=<a href='/topic/show?id=e52b3206cb' target=_blank style='color:#2F92EE;'>#Barrett#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3206, encryptionId=e52b3206cb, topicName=Barrett)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e94c20680600, createdName=yangeasy, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=)]
    2022-07-04 zhouqu_8
  6. [GetPortalCommentsPageByObjectIdResponse(id=1913964, encodeId=528d1913964ea, content=<a href='/topic/show?id=4684153e41f' target=_blank style='color:#2F92EE;'>#RET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15374, encryptionId=4684153e41f, topicName=RET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Tue Aug 16 18:43:22 CST 2022, time=2022-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057358, encodeId=f4bd205e35824, content=<a href='/topic/show?id=18982222db' target=_blank style='color:#2F92EE;'>#AJG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2222, encryptionId=18982222db, topicName=AJG)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2978132, createdName=minzju5052, createdTime=Mon Oct 24 14:43:22 CST 2022, time=2022-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970316, encodeId=617b19e0316fe, content=<a href='/topic/show?id=bc8d202929a' target=_blank style='color:#2F92EE;'>#不典型增生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20292, encryptionId=bc8d202929a, topicName=不典型增生)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5d70341, createdName=zhishijing, createdTime=Sat Feb 04 20:43:22 CST 2023, time=2023-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1898669, encodeId=6e7d1898669a4, content=<a href='/topic/show?id=e5062028978' target=_blank style='color:#2F92EE;'>#不典型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20289, encryptionId=e5062028978, topicName=不典型)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Mon Mar 20 23:43:22 CST 2023, time=2023-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437754, encodeId=184c143e7542c, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520109, encodeId=45491520109a2, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624634, encodeId=fbe116246346f, content=<a href='/topic/show?id=e52b3206cb' target=_blank style='color:#2F92EE;'>#Barrett#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3206, encryptionId=e52b3206cb, topicName=Barrett)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e94c20680600, createdName=yangeasy, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=)]
    2022-07-04 snowpeakxu
  7. [GetPortalCommentsPageByObjectIdResponse(id=1913964, encodeId=528d1913964ea, content=<a href='/topic/show?id=4684153e41f' target=_blank style='color:#2F92EE;'>#RET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15374, encryptionId=4684153e41f, topicName=RET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Tue Aug 16 18:43:22 CST 2022, time=2022-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057358, encodeId=f4bd205e35824, content=<a href='/topic/show?id=18982222db' target=_blank style='color:#2F92EE;'>#AJG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2222, encryptionId=18982222db, topicName=AJG)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2978132, createdName=minzju5052, createdTime=Mon Oct 24 14:43:22 CST 2022, time=2022-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970316, encodeId=617b19e0316fe, content=<a href='/topic/show?id=bc8d202929a' target=_blank style='color:#2F92EE;'>#不典型增生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20292, encryptionId=bc8d202929a, topicName=不典型增生)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5d70341, createdName=zhishijing, createdTime=Sat Feb 04 20:43:22 CST 2023, time=2023-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1898669, encodeId=6e7d1898669a4, content=<a href='/topic/show?id=e5062028978' target=_blank style='color:#2F92EE;'>#不典型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20289, encryptionId=e5062028978, topicName=不典型)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Mon Mar 20 23:43:22 CST 2023, time=2023-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437754, encodeId=184c143e7542c, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520109, encodeId=45491520109a2, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624634, encodeId=fbe116246346f, content=<a href='/topic/show?id=e52b3206cb' target=_blank style='color:#2F92EE;'>#Barrett#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3206, encryptionId=e52b3206cb, topicName=Barrett)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e94c20680600, createdName=yangeasy, createdTime=Mon Jul 04 07:43:22 CST 2022, time=2022-07-04, status=1, ipAttribution=)]
    2022-07-04 yangeasy

相关资讯

GIE: 射频消融可明显降低巴雷特食管低度不典型增生的进一步发展

巴雷特食管炎(BE)是食管腺癌的癌前病变,这种疾病的发病率不断上升。

Gastroenterology:巴雷特食管患者术后内镜随访间隔研究

依据本研究对巴雷特食管患者的组织学分类进行相应的术后内镜检查可使患者晚期不可切除食管癌风险降低至1/1000以下

Lancet Gastroen Hepatol:新简化局部射频消融治疗巴雷特食管效果评估

研究认为3×12 J/cm2简化局部射频消融治疗巴雷特食管的效果与标准治疗相当且不会增加患者治疗后食道狭窄风险

GUT:食管腺癌及巴雷特食管患者与临床相关的DNA甲基化亚型分析

研究人员对食管腺癌及巴雷特食管患者甲基化亚型进行了分析,证实了与临床相关的甲基化亚型特征,为食管腺癌患者的个体化治疗提供了依据

Gastroenterology:MiRNA检测在巴雷特食管诊断中的应用

研究发现,巴雷特食管患者存在特异的MiRNA过表达现象,是有效的巴雷特食管诊断方法,其中MIR194表达增加可能通过表观遗传机制参与疾病的发生

Gastroenterology:不同食管腺癌表型患者的预后差异

研究发现,食管腺癌伴巴雷特食管/肠上皮化生患者的预后较好,该研究结果对食管腺癌患者分层、临床治疗以及预后管理具有一定的指导意义