Neurology:中年高血压、糖尿病和吸烟会让人“变傻”!

2020-07-25 xujing 中国循环杂志

神经学杂志发表的一项研究提示,中年人群的心血管病危险因素,特别是高血压、糖尿病和吸烟或可能加快中年认知功能下降。

神经学杂志发表的一项研究提示,中年人群的血管病危险因素,特别是高血压、糖尿病和吸烟或可能加快中年认知功能下降。

研究发现,与非高血压患者相比,高血压患者的认知功能下降加快的风险增加了65%。

吸烟者比不吸烟的人,认知功能下降加快的风险增加了87%。

糖尿病患者比非糖尿病患者,认知功能下降加快风险增加1.5倍。

而且危险因素数量越多,认知功能下降加快风险也越高。

与没有心血管疾病危险因素者相比,有1-2种危险因素者,认知功能下降加快的风险增加了77%;有3种或更多危险因素者,风险增加了近3倍。

因此,研究者提醒,要预防中年人的认知能力下降,同样要控制这些可控的心血管病危险因素。

研究纳入2675名中年人,平均年龄50岁。高血压占31%,糖尿病占11%,肥胖占43%,高脂血症占9%和目前吸烟者占15%。

研究发现,5%的受试者在5年内认知能力下降加快。

Lancet杂志在2017年发表的痴呆防治决议报告中,根据最新估计,全球有近5000万人患痴呆症及阿尔兹海默症。到2050年,痴呆人数可能激增至1.32亿。而且,发展中国家痴呆人数增长迅速。

报告称,避免9种因素可预防35%的痴呆。包括:受教育超过15年、避免听力下降、不肥胖、中年时(45~65岁)血压不高、戒烟、不抑郁、糖尿病、规律锻炼身体和积极社交。

根据中国疾病负担报告,过去 11 年间,从死亡数变化来看,阿尔兹海默病增长了57.8%,在所有疾病中排名第五。

原始出处:

Kristine Yaffe, Amber L Bahorik 1, Tina D Hoang 2, et al.Cardiovascular Risk Factors and Accelerated Cognitive Decline in Midlife: the CARDIA Study.Neurology. 2020 Jul 15;10.1212/WNL.0000000000010078. doi: 10.1212/WNL.0000000000010078.

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    2020-09-15 咻凡

    能说通一个老年患者不吸烟不喝酒真的挺难的 需要语言的智慧

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=885473, encodeId=27e48854e3ba, content=能说通一个老年患者不吸烟不喝酒真的挺难的 需要语言的智慧, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Sep 15 14:17:54 CST 2020, time=2020-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=883987, encodeId=770888398e71, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76d12257050, createdName=12177770m58暂无昵称, createdTime=Wed Sep 09 22:07:06 CST 2020, time=2020-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2001089, encodeId=e1142001089dc, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Sun Jun 06 14:39:43 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=805153, encodeId=7a5b805153a0, content=厉害呀, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200722/c42cab9b2fa140b9a2881a0c31923a63/09844aaa242949fabe1c6290e273134f.jpg, createdBy=8ef15402156, createdName=ms5000000703521081, createdTime=Thu Jul 30 09:35:13 CST 2020, time=2020-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804604, encodeId=5649804604d3, content=发展中国家中年人压力大,特别是男性人群,对自身健康管理的依从性差。然后恶性循环,促使阿尔兹海默症增高。, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200726/689f5dfb6e5b4165b1a5156604f91964/518e32492fdf40689b7cc8c73fa0f600.jpg, createdBy=cc9a5402881, createdName=彭红, createdTime=Sun Jul 26 14:42:07 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043236, encodeId=d9a110432360a, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Jul 25 14:39:43 CST 2020, time=2020-07-25, status=1, ipAttribution=)]
    2020-09-09 12177770m58暂无昵称

    学习了

    0

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    2021-06-06 yinhl1978
  4. [GetPortalCommentsPageByObjectIdResponse(id=885473, encodeId=27e48854e3ba, content=能说通一个老年患者不吸烟不喝酒真的挺难的 需要语言的智慧, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Sep 15 14:17:54 CST 2020, time=2020-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=883987, encodeId=770888398e71, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76d12257050, createdName=12177770m58暂无昵称, createdTime=Wed Sep 09 22:07:06 CST 2020, time=2020-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2001089, encodeId=e1142001089dc, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Sun Jun 06 14:39:43 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=805153, encodeId=7a5b805153a0, content=厉害呀, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200722/c42cab9b2fa140b9a2881a0c31923a63/09844aaa242949fabe1c6290e273134f.jpg, createdBy=8ef15402156, createdName=ms5000000703521081, createdTime=Thu Jul 30 09:35:13 CST 2020, time=2020-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804604, encodeId=5649804604d3, content=发展中国家中年人压力大,特别是男性人群,对自身健康管理的依从性差。然后恶性循环,促使阿尔兹海默症增高。, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200726/689f5dfb6e5b4165b1a5156604f91964/518e32492fdf40689b7cc8c73fa0f600.jpg, createdBy=cc9a5402881, createdName=彭红, createdTime=Sun Jul 26 14:42:07 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043236, encodeId=d9a110432360a, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Jul 25 14:39:43 CST 2020, time=2020-07-25, status=1, ipAttribution=)]
    2020-07-30 ms5000000703521081

    厉害呀

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=885473, encodeId=27e48854e3ba, content=能说通一个老年患者不吸烟不喝酒真的挺难的 需要语言的智慧, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Sep 15 14:17:54 CST 2020, time=2020-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=883987, encodeId=770888398e71, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76d12257050, createdName=12177770m58暂无昵称, createdTime=Wed Sep 09 22:07:06 CST 2020, time=2020-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2001089, encodeId=e1142001089dc, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Sun Jun 06 14:39:43 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=805153, encodeId=7a5b805153a0, content=厉害呀, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200722/c42cab9b2fa140b9a2881a0c31923a63/09844aaa242949fabe1c6290e273134f.jpg, createdBy=8ef15402156, createdName=ms5000000703521081, createdTime=Thu Jul 30 09:35:13 CST 2020, time=2020-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804604, encodeId=5649804604d3, content=发展中国家中年人压力大,特别是男性人群,对自身健康管理的依从性差。然后恶性循环,促使阿尔兹海默症增高。, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200726/689f5dfb6e5b4165b1a5156604f91964/518e32492fdf40689b7cc8c73fa0f600.jpg, createdBy=cc9a5402881, createdName=彭红, createdTime=Sun Jul 26 14:42:07 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043236, encodeId=d9a110432360a, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Jul 25 14:39:43 CST 2020, time=2020-07-25, status=1, ipAttribution=)]
    2020-07-26 彭红

    发展中国家中年人压力大,特别是男性人群,对自身健康管理的依从性差。然后恶性循环,促使阿尔兹海默症增高。

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=885473, encodeId=27e48854e3ba, content=能说通一个老年患者不吸烟不喝酒真的挺难的 需要语言的智慧, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Sep 15 14:17:54 CST 2020, time=2020-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=883987, encodeId=770888398e71, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76d12257050, createdName=12177770m58暂无昵称, createdTime=Wed Sep 09 22:07:06 CST 2020, time=2020-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2001089, encodeId=e1142001089dc, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Sun Jun 06 14:39:43 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=805153, encodeId=7a5b805153a0, content=厉害呀, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200722/c42cab9b2fa140b9a2881a0c31923a63/09844aaa242949fabe1c6290e273134f.jpg, createdBy=8ef15402156, createdName=ms5000000703521081, createdTime=Thu Jul 30 09:35:13 CST 2020, time=2020-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804604, encodeId=5649804604d3, content=发展中国家中年人压力大,特别是男性人群,对自身健康管理的依从性差。然后恶性循环,促使阿尔兹海默症增高。, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200726/689f5dfb6e5b4165b1a5156604f91964/518e32492fdf40689b7cc8c73fa0f600.jpg, createdBy=cc9a5402881, createdName=彭红, createdTime=Sun Jul 26 14:42:07 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043236, encodeId=d9a110432360a, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Jul 25 14:39:43 CST 2020, time=2020-07-25, status=1, ipAttribution=)]
    2020-07-25 misszhang

    谢谢MedSci提供最新的资讯

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