Nat Commun:复旦学者统计,武汉新冠**波大流行的疾病负担和临床严重程度

2020-10-30 haibei MedSci原创

症状病例、就诊、住院和死亡的比率分别估计为每10万人796(95% CI:703-977)、489(472-509)、370(358-384)和36.2(35.0-37.3)。

截至2020年7月26日,全球已有188个国家受到2019年新型冠状病毒病(COVID-19)的影响,全球共报告15,745,102例COVID-19病例,644,661人死亡。COVID-19具有广泛的严重性。

在血清学确认的感染中,只有一部分会出现症状。一部分有症状的病例可能会寻求医疗护理,当他们可以通过监测系统确定时,需要住院治疗,甚至面临死亡。住院是一个重要的衡量标准,因为它决定了流行病对卫生保健系统造成的压力。此外,死亡人数与规划大流行病应对措施高度相关,因为死亡率是卫生当局通常旨在尽量减少的结果。

2019年新型冠状病毒病(COVID-19)首次在中国武汉被报道,最初一波密集的社区传播被干预措施切断。利用多个数据源,最近来自复旦大学的研究人员在Nature Communications杂志发文,估计了2019年12月1日至2020年3月31日武汉市COVID-19的疾病负担和按年龄划分的临床严重程度。

研究人员的估计考虑了实验室检测的敏感性、前瞻性社区筛查和医疗寻求行为。症状病例、就诊、住院和死亡的比率分别估计为每10万人796(95% CI:703-977)、489(472-509)、370(358-384)和36.2(35.0-37.3)。

武汉市发生的COVID-19疫情在住院率和死亡率方面比2009年流感大流行或季节性流感负担更高,临床严重程度与1918年流感大流行相似。

研究人员的比较将COVID-19大流行置于大背景之下,有助于指导干预策略,以及对COVID-19可能再次出现的准备工作。

 

原始出处:

Juan Yang et al. Disease burden and clinical severity of the first pandemic wave of COVID-19 in Wuhan, China. Nature Communications (2020). 

 

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    2021-03-12 liye789132251
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    2020-11-01 saikp
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    2020-10-31 qingzipost

    值得学习!

    0

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    2020-10-31 公卫新人

    新冠肺炎,疫情何时才能消失

    0

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