Gut:高收入国家的结肠癌和直肠癌生存率

2020-06-02 MedSci原创 MedSci原创

在一些高收入国家中,结肠癌和直肠癌患者的生存差异可能是由于一些国家的早期诊断、区域和远距离疾病的治疗差异以及诊断时年龄较大造成的。各国癌症登记实践的差异以及不同的分期系统可能会影响比较。

近日,消化病领域权威杂志Gut上发表了一篇研究文章,作为国际癌症基准评估合作伙伴关系(ICBP)SURVMARK-2项目的一部分,研究人员旨在根据年龄和诊断阶段提供七个高收入国家结肠癌和直肠癌患者生存率的最新估计。

研究人员分析了来自七个国家(澳大利亚、加拿大、丹麦、爱尔兰、新西兰、挪威和英国)的19个癌症登记中心2010-2014年期间诊断的386870名患者的数据。根据诊断分期、年龄和国家/地区评估了结肠癌和直肠癌患者1年和5年净生存率。

结肠癌和直肠癌患者(1年)和5年净生存率分别在(77.1%至87.5%)59.1%至70.9%和(84.8%至90.0%)61.6%至70.9%之间。在澳大利亚、加拿大和挪威,患者存活率一直较高,在加拿大和澳大利亚,转移性疾病患者的比例较小。对于区域性和远处结肠癌患者(1年)和5年生存率的国际差异最为明显,范围分别在(86.0%至94.1%)62.5%至77.5%以及(40.7%至56.4%)8.0%至17.3%之间。直肠癌观察到相似的结果。各国结肠癌和直肠癌的分期分布因国家而异,转移性疾病和诊断时年龄较大(不论分期)患者的生存率差异显著。

在一些高收入国家中,结肠癌和直肠癌患者的生存差异可能是由于一些国家的早期诊断、区域和远距离疾病的治疗差异以及诊断时年龄较大造成的。各国癌症登记实践的差异以及不同的分期系统可能会影响比较。

原始出处:

Marzieh Araghi.et al.Colon and rectal cancer survival in seven high-income countries 2010–2014: variation by age and stage at diagnosis (the ICBP SURVMARK-2 project). Gut.2020.http://dx.doi.org/10.1136/gutjnl-2020-320625

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    2021-04-18 duomaoke

    学习了!

    0

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    2020-08-18 lovetcm

    #结肠癌##直肠癌#患者(1年)和5年净生存率分别在(77.1%至87.5%)59.1%至70.9%和(84.8%至90.0%)61.6%至70.9%之间。确实远远高于中国,一方面早筛方面做的好,另外治疗更规范一些。

    0

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