Heart Rhythm:心电图有早复极的结构性心脏病患者猝死风险增3倍

2017-04-25 朱柳媛 中国循环杂志

既往研究表明,在普通人群中,心电图早复极可导致因心律失常死亡的风险增加。然而,早复极对于结构性心脏病患者的预后意义仍存在争议。

既往研究表明,在普通人群中,心电图早复极可导致因心律失常死亡的风险增加。然而,早复极对于结构性心脏病患者的预后意义仍存在争议。

中山大学附属第一医院吴素华等对19项观察性研究进行Meta分析后发现,在结构性心脏病患者中,早复极与室性心律失常和心原性猝死风险显着增加有关,但目前并不明确其中的机制。

研究者指出,“未来的研究应尝试去了解(早复极)致心律失常风险增加的准确机制,并将早复极引入结构性心脏病患者的风险分层中。”

分析显示,与没有早复极的患者相比,出现早复极的结构性心脏病患者发生室性心律失常/心原性猝死、室颤、心原性猝死的风险依次增加3.76倍、6.14倍、3.07倍。所有亚组分析结果与上述结果保持一致。

研究者还发现,心电图上前壁导联出现早复极伴J波抬高、有切迹、ST段水平或压低,意味着风险高。

这项Meta分析共包括7268例受试者,其中1127例出现室性心律失常或心原性猝死。

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    2017-04-27 zhaojie88
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    2017-04-27 slcumt

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