OCC2018:沈卫峰:复杂高危患者血运重建策略

2018-06-05 佚名 东方心脏病学会议

上海交通大学医学院附属瑞金医院沈卫峰教授指出,对于高危和复杂冠心病患者的治疗重在预防死亡和急性冠状动脉事件,以改善患者预后。同时尽量减轻患者症状严重程度和发作次数,以提高生活质量。

上海交通大学医学院附属瑞金医院沈卫峰教授指出,对于高危和复杂冠心病患者的治疗重在预防死亡和急性冠状动脉事件,以改善患者预后。同时尽量减轻患者症状严重程度和发作次数,以提高生活质量。

他强调,对于高危和复杂冠心病患者应首先进行评分。SYNTAXⅡ评分综合6个临床因素,预测左主干病变、复杂三支病变血运重建的远期死亡率优于SYNTAX评分,有利于心脏团队治疗决策。此外,优先应用新一代药物洗脱支架(DES)有利于降低再狭窄率,血管内超声(IVUS)评估支架大小、膨胀、定位有助于改善远期预后。Mini-crush比Culotte的不良心血管事件(MACE)/靶血管血运重建(TLR)相似,而ST(支架内血栓)发生率更低。术后应服用双联抗血小板治疗(DAPT)长于12个月。经皮冠状动脉介入治疗(PCI)后无论有无症状,3~12个月后均应复查冠状动脉造影。

PCI与CABG的选择问题怎样抉择?

PCI与CABG的选择问题怎样抉择?EXCEL临床试验结论显示,无保护左主干且SYNTAX积分低/重度患者,EES-PCI一级终点(3年死亡、卒中或MI)与CABG相似,30天不良事件少。对选择性无保护左主干患者可以考虑PCI,甚至优先应用。血运重建策略需由心脏团队具体决定。

复杂或高危MVD患者应用现代先进的技术进行完全血运重建可以达到最大的临床益处。研究显示,接受EES-PCI的MVD患者的MACE高于CABG,二者致死性出血未见明显差异。如完全血运重建,则MI发生率无差异。

杂交冠状动脉血运重建(HCR)具有一定优势,也有一些问题。LIMA-LAD能够提高PCI的安全性,此外HCR能够使更多高危患者完全血运重建,DES-CX/RCA能够避免大手术、降低再狭窄,减少对比剂肾病。然而,HCR的操作顺序、杂交手术室和费用都是实施HCR之前值得考虑的因素。

最后沈卫峰教授总结,高危/复杂患者血运重建前需进行风险分层,心脏团队或MDT决策。SYNTAX>33或糖尿病患者CABG远期预后优于PCI。SYNTAX评分<32分患者PCI与CABG主要终点相当,但TVR增多(疗效取决于操作者的经验和数量)。根据具体情况,力争实现功能学意义上的完全血运重建,而杂交冠状动脉血运重建能够优化完全血运重建的临床疗效。

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    2018-06-10 大爰

    好文章学习并分享!!

    0

  3. 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createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Tue Jun 05 23:37:11 CST 2018, time=2018-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321756, encodeId=3687321e56bc, content=不错的文章值得推荐一下了, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Tue Jun 05 23:36:42 CST 2018, time=2018-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321748, encodeId=b790321e48cd, content=杂交冠状动脉血运重建(HCR)具有一定优势.也有一些问题.LIMA-LAD能够提高PCI的安全性.此外HCR能够使更多高危患者完全血运重建.DES-CX/RCA能够避免大手术.降低再狭窄.减少对比剂肾病.然而.HCR的操作顺序.杂交手术室和费用都是实施HCR之前值得考虑的因素., beContent=null, objectType=article, channel=null, level=null, 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    2018-06-09 大爰

    好文章学习了谢谢分享!!

    0

  4. 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    2018-06-07 zhaojie88
  5. 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    2018-06-07 三生有幸9135

    学习一下谢谢

    0

  6. 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    2018-06-06 wangjianli2934

    学习了.

    0

  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Tue Jun 05 23:37:11 CST 2018, time=2018-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321756, encodeId=3687321e56bc, content=不错的文章值得推荐一下了, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Tue Jun 05 23:36:42 CST 2018, time=2018-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321748, encodeId=b790321e48cd, content=杂交冠状动脉血运重建(HCR)具有一定优势.也有一些问题.LIMA-LAD能够提高PCI的安全性.此外HCR能够使更多高危患者完全血运重建.DES-CX/RCA能够避免大手术.降低再狭窄.减少对比剂肾病.然而.HCR的操作顺序.杂交手术室和费用都是实施HCR之前值得考虑的因素., beContent=null, objectType=article, channel=null, level=null, likeNumber=15, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Jun 05 23:17:49 CST 2018, time=2018-06-05, status=1, ipAttribution=)]
    2018-06-06 飛歌

    厉害了我的哥

    0

  8. 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likeNumber=15, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Jun 05 23:17:49 CST 2018, time=2018-06-05, status=1, ipAttribution=)]
    2018-06-05 清风拂面

    谢谢分享学习

    0

  9. 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    2018-06-05 131****2916

    不错的文章值得推荐一下了

    0

  10. 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createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Jun 07 13:31:00 CST 2018, time=2018-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=322141, encodeId=9e00322141e5, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Thu Jun 07 06:45:19 CST 2018, time=2018-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321805, encodeId=8bb43218058e, content=学习了., beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=2d7e2114920, createdName=wangjianli2934, createdTime=Wed Jun 06 05:29:01 CST 2018, time=2018-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321771, encodeId=e6b9321e7161, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed Jun 06 00:09:19 CST 2018, time=2018-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321763, encodeId=d9a3321e63f4, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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likeNumber=15, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Jun 05 23:17:49 CST 2018, time=2018-06-05, status=1, ipAttribution=)]
    2018-06-05 有备才能无患

    杂交冠状动脉血运重建(HCR)具有一定优势.也有一些问题.LIMA-LAD能够提高PCI的安全性.此外HCR能够使更多高危患者完全血运重建.DES-CX/RCA能够避免大手术.降低再狭窄.减少对比剂肾病.然而.HCR的操作顺序.杂交手术室和费用都是实施HCR之前值得考虑的因素.

    0

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