JCC: 使用二甲双胍可降低2型糖尿病患者的患炎症性肠病风险

2020-08-28 MedSci原创 MedSci原创

近两年越来越多的研究发现，二甲双胍不仅具有降血糖的作用，还有抗衰老抗肿瘤延长寿命等作用。

近两年越来越多的研究发现，二甲双胍不仅具有降血糖的作用，还有抗衰老抗肿瘤延长寿命等作用。最近有研究发现他居然还能给肠道细菌带来正能量，降低炎症性肠病的发病风险。世界微生态学会主席光冈知足教授曾说过：肠道病是“万病之源”；肠道菌群失调是罪魁祸首；好的肠道菌群就像是肥沃的土壤，通过它的滋养，可以让健康之树长得枝繁叶茂。而坏的肠道菌群就像是布满垃圾和有毒物质的贫瘠河道，会让树变得叶黄枝瘦，在人就表现为罹患很多疾病。

最近发表在《Journal of Crohn's and Colitis》一篇研究对服用二甲双胍的糖尿病患者的炎症性肠病的发病率进行了长期随访调查。在研究中研究人员共对340211名曾经使用过二甲双胍患者和24478名从未使用过二甲双胍的患者进行了随访。通过Cox回归估计危险比。

使用过二甲双胍患者被诊断出有6466个IBD病例，从未使用过二甲双胍的患者诊断出750例IBD病例。发病率分别为每100000人年412.0和741.3，曾经使用二甲双胍与相比于未使用的危险比为0.55（95％可信区间：0.51-0.60）。因此，综合以上的研究结果我们发现在接受二甲双胍治疗的2型糖尿病患者中IBD发生风险明显降低。

原始出处：

Chin-Hsiao Tseng. Et al. Metformin use is associated with a lower risk of inflammatory bowel disease in patients with type 2 diabetes mellitus.Journal of Crohn's and Colitis.2020.

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2020-08-30 aids213

#2型糖尿病患者#

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2020-08-30 xue8604

#糖尿病患者#

25 0
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2020-08-30 12498dd9m15暂无昵称

#炎症性#

27 0
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2020-08-29 misszhang

二甲双胍，神药！

50 0
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2020-08-29 misszhang

谢谢MedSci提供最新的资讯

66 0
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2020-08-28 heli0118

#二甲双胍# ，神奇之药。#二甲双胍#可降低#2型糖尿病#患者的#炎症性肠病#的发生风险。

182 0
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2020-08-28 lovetcm

#二甲双胍#减少#炎症性肠病#风险

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