美国批准Janssen的艾滋病毒药物Symtuza

2018-07-18 MedSci MedSci原创

Janssen的Symtuza已被美国监管机构批准为第一个也是唯一一个完整的,基于darunavir的单片治疗方案,用于治疗成人HIV。根据Janssen的说法,单项治疗方案有能力提高依从性并减轻药物负担。它说:"在为提高耐受性和便利性而设计的配方中,darunavir的耐药性已经被证明是有效的防护屏障。""作为临床医生,我们可能并不总是能够全面了解患者的健康状况或他们在做出治疗决策时产生耐药性的



Janssen的Symtuza已被美国监管机构批准为第一个也是唯一一个完整的,基于darunavir的单片治疗方案,用于治疗成人HIV。

根据Janssen的说法,单项治疗方案有能力提高依从性并减轻药物负担。它说:"在为提高耐受性和便利性而设计的配方中,darunavir的耐药性已经被证明是有效的防护屏障。"

"作为临床医生,我们可能并不总是能够全面了解患者的健康状况或他们在做出治疗决策时产生耐药性的风险,"北卡罗来纳大学艾滋病研究中心医学教授兼临床核心主任Joseph Eron说。

"在关键的III期临床试验中,Symtuza成功治疗了那些开始治疗的患者,以及那些在抗逆转录病毒(ARV)治疗中被稳定抑制的患者--包括具有更复杂治疗史或先前病毒失败的患者 - 证明其作为各种患者的重要新治疗选择的潜力。

该批准是基于两项为期48周的III期研究的数据,这些研究评估了Symtuza与没有抗逆转录病毒史的成人(AMBER)和病毒学抑制成人(EMERALD)的对照方案的安全性和有效性。

两项试验的结果均显示Symtuza有效且耐受良好,高达95%达到或维持病毒抑制。


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    2018-07-19 131****1460

    学习了受益匪浅

    0

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    2018-07-19 kafei

    学习了谢谢

    0

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    2018-07-19 liumin1987

    抗艾滋病病**物为艾滋病的治疗提供了选择

    0

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    2018-07-19 zb1235672

    学习了

    0

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