Ann Surg:微创食管切除术 vs 开胸食管切除术治疗的晚期食管癌患者的5年存活率

2021-01-25 MedSci原创 MedSci原创

晚期食管癌,该选择微创食管切除术还是开胸食管切除术?

食管癌是全球常见的癌症之一,5年总体存活率不足20%,是癌症相关死亡的第七大原因。无远处扩散的晚期食管癌多采用手术切除治疗,手术方式有微创食管切除术(MIE)和开胸食管切除术(OE)。本研究旨在比较两种手术方式后食管癌患者的5年存活率。

本研究是一项基于人群的队列研究,纳入2010-2016年间在瑞典或芬兰接受择期食管癌切除术的几乎所有患者,随访至2020年。

共1264例患者,其中470例(37.2%)接受了MIE,794例(62.8%)接受了OE。与OE相比,MIE与5年全因死亡率降低18%相关(校正风险比[HR] 0.82,95% CI 0.67-1.00;P=0.048)。混合MIE相比OE后的5年全因死亡率的校正HR为0.87(95% CI 0.68-1.11);而完全MIE相比OE后的全因死亡率的校正HR更低,仅为0.77(0.60-0.98)。

综上,这项两国研究表明,采用MIE治疗的食管癌患者的5年存活率明显高于采用OE治疗的患者,而且完全MIE比混合MIE对生存预后的好处更大

原始出处:

Gottlieb-Vedi Eivind,Kauppila Joonas H,Mattsson Fredrik et al. Long-term survival in esophageal cancer after minimally invasive esophagectomy compared to open esophagectomy. Ann Surg, 2021, https://doi.org/10.1097/SLA.0000000000004645.

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  5. 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    2021-01-27 vera_1203
  6. 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    2021-01-27 zhouqu_8
  7. 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  8. 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    2021-01-25 ms9000000784262906

    学习了

    0

  9. 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    2021-01-25 ms6000000976382808

    学习了

    0

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