Allergy Asthma Clin Immunol:秋季花粉期,中国草原城市和非草原城市的慢性鼻炎患者情况调查

2021-10-17 AlexYang MedSci原创

比较了中国包头(草原城市)和北京(非草原城市)在秋季花粉季节,慢性鼻炎患者的相关情况。

呼吸道疾病患者的症状会受到当地环境因素的影响。已有研究表明,草原地区过敏性鼻炎的发病率明显高于非草原地区

近期,来自首都医科大学的研究人员在《Allergy Asthma Clin Immunol》上发表文章,比较了中国包头(草原城市)和北京(非草原城市)在秋季花粉季节,慢性鼻炎患者的相关情况

研究人员对在秋季花粉期,到包头医学院第二附属医院和北京同仁医院就诊的1170名和1232名慢性鼻炎患者,进行了问卷调查和过敏原检测;收集了有关病史、症状严重程度、诊断和治疗信息。

包头市和北京市的主要过敏原分布图

结果发现,包头市的中度到重度慢性鼻炎和哮喘患者均多于北京市的患者(P<0.001)。艾蒿是两个地区最丰富的过敏原,但包头市的室外过敏原过敏的患者人数高于北京(P<0.001)。北京的室内过敏原过敏占相当大的比例,尤其是尘螨(33.4%)。对于过敏性鼻炎患者来说,包头市患者的鼻塞、鼻痒和流鼻涕比北京市患者更严重(P<0.001)。在包头和北京,过敏(P<0.001 vs. P=0.004)和合并哮喘(P=0.049 vs. P=0.005)是影响慢性鼻炎严重程度的共同因素。在包头,年龄(rs=0.195,P<0.001)和家族过敏史(P=0.010)与症状严重程度有关。包头市接受口服抗组胺药、鼻腔皮质激素和手术治疗的患者明显多于北京(P<0.001),但包头市接受过敏免疫治疗的人数较少(P=0.004),治疗后症状控制情况也比北京差(P<0.001)

包头市和北京市慢性鼻炎患者的诊断和治疗比较

综上所述,在秋季花粉期,包头和北京的过敏原谱存在着显著的差异。过敏和合并哮喘是影响临床症状严重程度的共同因素。由于花粉暴露,包头的患者出现了更严重的临床症状,且治疗结果并不理想。原始可能是花粉暴露的影响,医疗服务差异以及治疗方式的差异。

原始出处:

Xu Xu, Long Qin, Lei Ren et al. Comparative analysis of chronic rhinitis patient profiles during autumn pollen season between grassland and non-grassland cities in North China. Allergy Asthma Clin Immunol. Oct 2021

 

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    2022-03-30 skhzy
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    2021-10-18 膀胱癌
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自20世纪60年代以来,全球过敏性疾病的发病率明显增加。该增长与环境因素有关,如空气污染物、空气中的过敏原、烟雾和不同的遗传背景,其中空气污染对人类健康的影响已成为主要的全球环境问题。颗粒物(PM)是