关于奥美拉唑,你还有疑问吗?

2016-07-20 刘治军 药师360

1、奥美拉唑的作用机理是什么?老百姓特别想知道很多药它是怎么来治病的,对于奥美拉唑来说,它用专业的词汇就是说,它能够抑制一个叫胃H+-K+-ATP酶,又叫质子泵。简单的说就是这个泵,它能够把钾离子泵到细胞内,把细胞内的氢离子泵出来,然后这个氢离子释放到胃中,就形成了我们所说的胃酸。奥美拉唑就是抑制了这个泵,让这个泵不能把氢离子泵出来,这种情况下,就造成了这个胃内的PH升高,把胃酸环境降下去,起

1、奥美拉唑的作用机理是什么?

老百姓特别想知道很多药它是怎么来治病的,对于奥美拉唑来说,它用专业的词汇就是说,它能够抑制一个叫胃H+-K+-ATP酶,又叫质子泵。简单的说就是这个泵,它能够把钾离子泵到细胞内,把细胞内的氢离子泵出来,然后这个氢离子释放到胃中,就形成了我们所说的胃酸。奥美拉唑就是抑制了这个泵,让这个泵不能把氢离子泵出来,这种情况下,就造成了这个胃内的PH升高,把胃酸环境降下去,起到一个抑制胃酸的作用。很多的疾病可能发生机制都跟胃酸过多有关,它通过抑制胃酸分泌的这个环节,就可以治疗一些胃酸过多的疾病。

2、奥美拉唑主要治疗什么病?

奥美拉唑它是一个抑制胃酸分泌的药,所以跟胃酸分泌过多相关的疾病,它都可以治疗。比如说我们最常见的,叫胃溃疡,还有十二指肠溃疡,这都是跟胃酸分泌过多有关,奥美拉唑可以很好的治疗这两种溃疡。还有一种病,我们叫它胃食管反流,这种病其实也非常的可怕,如果胃酸长期反流的话,会造成食管的癌变,所以我们也可以用奥美拉唑,抑制胃酸的分泌,来治疗胃食管反流。还有,大家现在可能都注重健康,每年都去查体,查体以后,发现幽门螺杆菌阳性,这个东西会造成胃溃疡。这种情况下,我们临床根据情况,可能会建议患者根除幽门螺杆菌。我们的治疗方案里面,就已经含有一个抑制胃酸的药,通常就是奥美拉唑,还有其他的一些拉唑等等。

3、奥美拉唑片、胶囊和注射液有什么区别?

奥美拉唑的剂型比较的多,有胶囊,有片剂,还有就是不能口服的患者,可能需要一些静脉注射的,还有静脉滴注的。通常就是这几种,比如说我可以做成肠溶的片剂,也可以做成肠溶的胶囊,还可以用于紧急情况下,直接往血管里输的一些静脉的制剂。

从剂型的角度来说,比较复杂,比如说奥美拉唑这个药,在胃中它不稳定,因为奥美拉唑本身是一个弱碱性的药物,在胃中跟胃酸的作用下,就会分解成一种游离的带离子的东西而不容易吸收,而且容易被破坏,所以绝大多数的奥美拉唑制剂,都会制成肠溶制剂,也就是说让奥美拉唑在肠道内溶解,释放出来,然后吸收,所以这是肠溶制剂。

还有一些患者,比如说处于昏迷状态,外伤、手术,还没醒过来,麻醉状态没醒过来,为了减少应激性的消化道出血,可能会给他用奥美拉唑,这种情况下他没有办法口服,就只能给他静脉给药,从不同的剂型来说,主要是考虑到它的用途不一样,患者的情况不一样。

4、奥美拉唑怎么服用效果好一些?

奥美拉唑在胃中不太稳定,因为胃中是一个酸性的环境,它本身是一个碱性的药物,在胃中容易破坏掉它的一些结构,造成吸收困难,造成药物的降解,所以往往都会做成肠溶片。基本上所有的肠溶片,我们都建议一定要餐前服用,或者叫空腹服用。

所谓的空腹状态,比如说前一天晚上吃完饭以后,一直没吃饭,大致保持八到十个小时,胃中没有食物,到第二天早上的状态,就叫空腹状态。在空腹状态下,奥美拉唑通过胃中的酸性环境,肠溶片不会在胃里溶解,它会蠕动到小肠的碱性环境中,才能够溶解释放吸收。

如果餐后服用,食物会把胃酸稀释,胃中的酸性环境会减弱。改变了酸性环境以后,肠溶胶囊也好,肠溶片也好,它容易在胃中就释放出来了。实际上它还没到达小肠,只是在胃中。这种情况下,就会引起对胃的一些刺激,甚至胃酸的环境会把它破坏掉,影响到它的吸收。

所以一般来说,如果我们口服奥美拉唑,一般会要求患者在早上空腹服用,如果每天服用一次还不行,需要晚上再加一片的话,那就需要在晚饭前,或者说在睡前再服一片,总之是要保证我们的胃肠道里食物尽可能的少,胃中的碱性环境要尽可能的低,这样它才不会在胃中就错误的释放,而会到肠道中释放。

5、奥美拉唑和哪些药不能同时服用?

这是一个比较复杂的问题,老百姓也非常关注,就是药物和药物相互作用的问题。奥美拉唑肠溶片,它的吸收仅仅局限在小肠中。如果我们口服了一个药物,这个药物是一个全消化道的动力药,比如莫沙必利,它是促进整个胃肠道的蠕动,加快食物和其他东西的排出,这两个药物合用之后会导致奥美拉唑在肠道中停留的时间减少,吸收的程度可能就会减少,可能会影响到它的疗效。因此,我们用奥美拉唑,早上起来空腹服用的时候,尽可能不与这种胃肠动力药合用。

除了胃肠动力药之外,还一些药物,比如可以直接在胃中中和胃酸的抗酸药,如氢氧化铝、氢氧化镁,以及他们的复方药物铝镁加等,这些药物可以直接把胃中的pH值升高。我们这时候再服用奥美拉唑,就会导致奥美拉唑在胃中就可能会溶解出来。因此,抗酸药不宜同时和奥美拉唑同时服用。

除此之外,还有一些更复杂的,比如因为心肌梗死放了支架的患者,为了预防支架里再形成血栓,通常会服用一些药,叫抗血栓药,保证他支架内不会再形成血栓。其中的一个抗血栓药叫氯吡格雷,它在体内,发挥它的抗血栓作用,需要经过有一步的代谢活化,奥美拉唑又恰好能够抑制它的代谢活化,会导致它没有抗血小板活性,那么就容易形成血栓。这种情况下,奥美拉唑不适合跟像氯吡格雷这一类的抗血小板聚集的药物合用。这些问题比较的专业,最好去各个医院的门诊咨询药师。

6、奥美拉唑会有哪些常见不良反应?

奥美拉唑,首先它是作用于消化道的一个药,它最常见的不良反应,就是消化道的一些症状。比如说有人首次服用以后,可能会出现腹痛、腹泻,也有一些人可能会出现便秘等等。

还有就是这个药还可能会引起个别患者出现头痛。还有一些就是最最常见的,过敏,对某个药物过敏会出现皮疹搔痒等等。如果出现这种症状,可以咨询一下医生或药师,到底能不能再接着用。有一些出现了不良反应,或者说副作用以后,必须要停掉。比如出现了皮疹,这是一个非常可怕的信号,就是说我身体对它不耐受,继续服用可能会造成一些更严重的损害。如果单纯是消化道的症状,比如说出现拉了两次肚子,或者说肚子疼了一会儿,那么我们可以尝试着观察一下,看看是不是接着服用以后,就能够好转,这种情况下是可以继续服用的。

借这个机会,也跟老百姓科普一下,一般来说我们服用一个药物以后,总会或多或少出现一些不良反应,一些轻微的不良反应,特别是刚才像我说的,像消化道的一些刺激症状,或者一过性的头痛,这些一般来说,还可以尝试着再观察治疗。如果出现了另外一些状况,比如说出现了皮疹,前胸后背肩膀胳膊出现相对大面积的皮疹的时候,就是一个比较严重的信号,这种情况下,就是对于奥美拉唑来说,赶紧停药。

对于一些治疗其他疾病的药物,比如说作用于心率的,作用于血压的,不能立即停药,但可以立即去找医生,找药师,大家一起来看,判断一下出现的这个症状,是不是跟你服药有关,是不是一个不良反应。如果确实是不良反应的话,那可能就要停掉,换成其他的药。

7、服用奥美拉唑有哪些禁忌?

奥美拉唑的禁忌症,不是特别多,它的产品说明书里提示,对哺乳的妇女,因为奥美拉唑是一个弱碱性的成分,它可以随着弱碱性的乳汁分泌。在这种情况下,吃奶吃得多了,可能会对婴幼儿有一定的影响。但是因为没有确切的证据能够证明它是不是安全,所以一般来说,哺乳妇女应该慎用或者禁用。我们看到它的产品说明书既然说怀孕的妇女其实是可以用的,也就是说奥美拉唑在孕妇的胎儿八个月、十个月大了,也可以用。如果一个产品,在产品说明书里边能这么大胆的说,孕妇可以用的话,它的安全性相对来说还是很好的,那么这一类人可以用。

说到禁忌的话,正在服用氯吡格雷的人放了支架的,或者说做了搭桥的这一类人,需要用氯吡格雷来抗凝、抗血小板聚集的,这一类人群不适合用。因为用了它以后,会造成抗血小板的作用减弱,或者作用消失,这种情况下就可能出现血栓事件。

奥美拉唑的代谢,主要是在肝中,也就是说我们肝脏对它进行解毒,代谢成若干的东西。这些代谢产物,要通过肾脏来排泄,所以肾功能严重不全的患者,我们也是建议避免用这个药。因为肾功能不全了,这些废物代谢不出来,会造成蓄积中毒。轻度的肾功能不全,其实还是可以用的。具体说肾功能现在是个什么情况,应该进一步咨询药师,或者咨询医生,给你进行评分分级。比如说你现在处于一个慢性肾病的哪一级哪一期,然后来确定,到底是不是可以使用奥美拉唑。

8、服用奥美拉唑要注意哪些事?

奥美拉唑在服用的时候,首先尽可能保证是在空腹的状态,或者说餐前的状态。比如说我会在早上起来服用,或者早饭前,或者在晚饭前,这主要是为了保证它不在胃中释放出来,对胃产生刺激作用。保证它能在肠道中释放出来,因为这个药是在肠道中吸收的,胃是不能吸收的。

曾经有一个病人,他问过我,说一个治胃病的药,干嘛非要做成肠溶片,在肠道中才吸收,可不可以直接在胃中释放出来,然后作用于胃壁来抑制胃酸?这个问题问得很好,所有的奥美拉唑,并不是服用后直接在胃中发挥作用的,而是先吸收到血液中,随着血液的循环到达胃壁细胞,然后在胃壁细胞细胞膜上发挥抑制质子泵的作用,减少胃酸的分泌。我们一定要强调的是,要在空腹状态下服用,然后尽可能让它在肠道中释放,吸收效果会更好一些。同时不宜把肠溶药片掰开服用。

9、奥美拉唑可以长期服用吗?

从说明书、从我们所关注的奥美拉唑长期服用的一些不良反应来说,还是应该有一个度。比如说对于胃溃疡,说明书上说,可以服用两周左右,如果两周左右效果不好,还可以接着再服用两周。对于十二指肠溃疡,可以服用一到两周,因为十二指肠溃疡更容易愈合,而且十二指肠溃疡,很少会出现癌变。胃溃疡患者使用奥美拉唑治疗,治疗一定时期,需要再重复做个胃镜,看一下溃疡有没有消失。

对于胃食管反流,疗程就更长了,可以到四周,可以到六周,必要的时候可以使用八周,也就是两个月。当这些病治疗非常好,溃疡也愈合了,反流也不见了,一定要停一下药。如果长期用药,比如连续使用三个月,六个月,甚至几年的话,那么一些长期的问题会出来,比如说胃在正常情况下是一个酸性的环境,这是上天在造我们人类的时候,就给它一个酸性的环境,让它对一些食物达到很好的消化的过程。如果长期人为地抑制胃酸分泌,会造成胃黏膜萎缩,可能引起肿瘤,或其他的东西,所以不太适合长期吃奥美拉唑。具体服用多久,还是要跟医生和药师一起来商量。

10、奥美拉唑一次服用过量怎么办?

相对来说奥美拉唑的安全性非常高。药品的说明书特意说明,在前期的研究中发现,有的患者一下子服用了十片,也就是说200毫克,都没有出现明显的毒副作用。它的安全性相对来说是比较高的,如果误服了几片,或者是其他的情况,只需要进行观察。因为它的安全性很高,不需要紧急洗胃,或者进行特殊的处理。

11、奥美拉唑多长时间一个疗程?

疗程与疾病有关,从消化道溃疡的一些诊疗指南,也从临床的具体情况上来说,十二指肠溃疡最容易愈合,所以它适合4-6周,也就是连续服用4-6周。胃溃疡相对来说也容易愈合,它需要6-8周。对于胃食管反流,也就是医学上说的GERD,这个病时间相对比较长,最长可以8-12周,也就是说基本上快到三个月。当然,我们看到奥美拉唑的说明书上,没有说可以用这么长,但是它说一个疗程下来,如果效果不好,还可以再接着服用第二个疗程,那么时间上也是能达到的。比如消化道十二指肠溃疡,一到两周以后效果不好,你可以再接着服一个疗程,也就到了二到四周。

12、服用奥美拉唑症状减轻后可以自行减药或停药吗?

这是一个很好的问题。我觉得是这样,从老百姓的角度来说,服药一定要遵医嘱,也就是要听话。因为有的时候,主观上感觉胃疼轻了,饥饿的时候,这种饥饿痛也会减轻,我可能会觉得是不是溃疡好了。但是那个时候,其实是没有证据的,而且你没有医生的经验多。我觉得老百姓不能因为自己主观上觉得症状减轻了,就私自把药停掉,这样其实对治疗后果是不利的。我觉得应该最起码跟医生说一下,医生判断一下,疗程够不够,或者必要的时候,我再给你做个胃镜,做个肠镜,看一下溃疡好了没有。

13、奥美拉唑可以与消炎药同服吗?

如果消炎药说的是一些抗菌药物,那么到目前为止,抗菌药物和奥美拉唑之间很少有不良的药物相互作用,是可以服用的。一个典型的例子就是,我们在根除幽门螺杆菌的时候,除了选择奥美拉唑这一大类的质子泵抑制剂,还会选择克拉霉素,阿莫西林,或者甲硝唑,这都是些老百姓说的消炎药,我们说的就叫抗菌药物,它们必须要一起合用,再加上一个铋剂,也就是保护胃黏膜的,然后促进幽门螺杆菌杀死的一个成分,一般都是三联或四联,这种情况下是可以合用的。

14、什么是药物拮抗作用?

这个问题相对专业一点。比如说某一个药物,我吃下去以后,能够促进我的腺体的分泌,比如有机磷中毒的人就往往流涎,大量的唾液分泌,以及气管内黏液的分泌,这是因为有机磷,或者说某些药物,作用于这个腺体,让这个腺体拼命的来分泌。那么如果另外一个药物,比如说我们说的阿托品,它正好来抑制,来拮抗了这个有机磷,或者说某一些药物的作用,让它对这个腺体分泌的作用消失了,那么这种作用,比如阿托品对于有机磷的这个作用,就叫一个拮抗。简单的说,用了有机磷,腺体就分泌了;用了阿托品,腺体就不分泌了,就可以说阿托品能够拮抗有机磷的作用。这也是为什么有机磷中毒,我们一定要给患者打阿托品,达到一个阿托品化的状态,这就是拮抗。

15、奥美拉唑注射液为什么会变红?


奥美拉唑是一个非常不稳定的药物,它很容易在酸性环境中发生降解。如果某一个溶媒,它的pH值偏低的话,那么在这个溶媒的环境中,奥美拉唑可能会降解为奥美拉唑硫醚等等这些成分,这些成分就容易出现一些颜色上的变化。


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  1. [GetPortalCommentsPageByObjectIdResponse(id=102516, encodeId=1b681025164a, content=学习了,原来肠溶片是这个原理的 <br> , beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2b11940953, createdName=可以肥下去, createdTime=Tue Aug 23 10:10:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96768, encodeId=b07996e6812, content=很好学习了,就是想详细了解关于其他剂型和溶媒啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRtNT7AWKboIfjpeY6Nw6lNxAc4w1aibutHSqCJ2c3AbwfqpRia4IrnzU2mK3Ojx2Har8AUUyhC0kl7/0, createdBy=ecc31722157, createdName=1decafd9m46(暂无匿称), createdTime=Sun Aug 07 17:45:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96279, encodeId=06a2962e9cc, content=值得学习和分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b2c1297487, createdName=ghy_happy, createdTime=Sat Aug 06 07:27:00 CST 2016, time=2016-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=94489, encodeId=7d8d9448988, content=肠溶片的原理让人印象深刻。, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59301669806, createdName=诊艾, createdTime=Sun Jul 24 16:09:00 CST 2016, time=2016-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284405, encodeId=379b1284405d0, content=<a href='/topic/show?id=3db5445e031' target=_blank style='color:#2F92EE;'>#奥美拉唑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44570, encryptionId=3db5445e031, topicName=奥美拉唑)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ced3193, createdName=freve, createdTime=Fri Jul 22 05:48:00 CST 2016, time=2016-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93973, encodeId=7c99939e3fd, content=普及知识,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zGdN1x8J6HqtUI2Gpibk3sfIIBhZchAhjoiaCQlficdtQTnEqYncy3GVEMPIOJwD7t0mO2KfYGMgkIg/0, createdBy=86081727811, createdName=4546wk, createdTime=Wed Jul 20 23:30:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93974, encodeId=8299939e437, content=值得一看, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zGdN1x8J6HqtUI2Gpibk3sfIIBhZchAhjoiaCQlficdtQTnEqYncy3GVEMPIOJwD7t0mO2KfYGMgkIg/0, createdBy=86081727811, createdName=4546wk, createdTime=Wed Jul 20 23:30:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93961, encodeId=6a6993961a2, content=普及知识,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160803/IMG57A185CE577478201.jpg, createdBy=bad41730551, createdName=小青虫, createdTime=Wed Jul 20 21:33:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93949, encodeId=70f8939498e, content=学习学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jul 20 21:25:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93872, encodeId=6f06938e204, content=好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Jul 20 19:10:00 CST 2016, time=2016-07-20, status=1, ipAttribution=)]
    2016-08-23 可以肥下去

    学习了,原来肠溶片是这个原理的

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=102516, encodeId=1b681025164a, content=学习了,原来肠溶片是这个原理的 <br> , beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2b11940953, createdName=可以肥下去, createdTime=Tue Aug 23 10:10:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96768, encodeId=b07996e6812, content=很好学习了,就是想详细了解关于其他剂型和溶媒啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRtNT7AWKboIfjpeY6Nw6lNxAc4w1aibutHSqCJ2c3AbwfqpRia4IrnzU2mK3Ojx2Har8AUUyhC0kl7/0, createdBy=ecc31722157, createdName=1decafd9m46(暂无匿称), createdTime=Sun Aug 07 17:45:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96279, encodeId=06a2962e9cc, content=值得学习和分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b2c1297487, createdName=ghy_happy, createdTime=Sat Aug 06 07:27:00 CST 2016, time=2016-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=94489, encodeId=7d8d9448988, content=肠溶片的原理让人印象深刻。, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59301669806, createdName=诊艾, createdTime=Sun Jul 24 16:09:00 CST 2016, time=2016-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284405, encodeId=379b1284405d0, content=<a href='/topic/show?id=3db5445e031' target=_blank style='color:#2F92EE;'>#奥美拉唑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44570, encryptionId=3db5445e031, topicName=奥美拉唑)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ced3193, createdName=freve, createdTime=Fri Jul 22 05:48:00 CST 2016, time=2016-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93973, encodeId=7c99939e3fd, content=普及知识,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zGdN1x8J6HqtUI2Gpibk3sfIIBhZchAhjoiaCQlficdtQTnEqYncy3GVEMPIOJwD7t0mO2KfYGMgkIg/0, createdBy=86081727811, createdName=4546wk, createdTime=Wed Jul 20 23:30:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93974, encodeId=8299939e437, content=值得一看, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zGdN1x8J6HqtUI2Gpibk3sfIIBhZchAhjoiaCQlficdtQTnEqYncy3GVEMPIOJwD7t0mO2KfYGMgkIg/0, createdBy=86081727811, createdName=4546wk, createdTime=Wed Jul 20 23:30:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93961, encodeId=6a6993961a2, content=普及知识,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160803/IMG57A185CE577478201.jpg, createdBy=bad41730551, createdName=小青虫, createdTime=Wed Jul 20 21:33:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93949, encodeId=70f8939498e, content=学习学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jul 20 21:25:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93872, encodeId=6f06938e204, content=好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Jul 20 19:10:00 CST 2016, time=2016-07-20, status=1, ipAttribution=)]
    2016-08-07 1decafd9m46(暂无匿称)

    很好学习了,就是想详细了解关于其他剂型和溶媒啊

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=102516, encodeId=1b681025164a, content=学习了,原来肠溶片是这个原理的 <br> , beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2b11940953, createdName=可以肥下去, createdTime=Tue Aug 23 10:10:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96768, encodeId=b07996e6812, content=很好学习了,就是想详细了解关于其他剂型和溶媒啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRtNT7AWKboIfjpeY6Nw6lNxAc4w1aibutHSqCJ2c3AbwfqpRia4IrnzU2mK3Ojx2Har8AUUyhC0kl7/0, createdBy=ecc31722157, createdName=1decafd9m46(暂无匿称), createdTime=Sun Aug 07 17:45:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96279, encodeId=06a2962e9cc, content=值得学习和分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b2c1297487, createdName=ghy_happy, createdTime=Sat Aug 06 07:27:00 CST 2016, time=2016-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=94489, encodeId=7d8d9448988, content=肠溶片的原理让人印象深刻。, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59301669806, createdName=诊艾, createdTime=Sun Jul 24 16:09:00 CST 2016, time=2016-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284405, encodeId=379b1284405d0, content=<a href='/topic/show?id=3db5445e031' target=_blank style='color:#2F92EE;'>#奥美拉唑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44570, encryptionId=3db5445e031, topicName=奥美拉唑)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ced3193, createdName=freve, createdTime=Fri Jul 22 05:48:00 CST 2016, time=2016-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93973, encodeId=7c99939e3fd, content=普及知识,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zGdN1x8J6HqtUI2Gpibk3sfIIBhZchAhjoiaCQlficdtQTnEqYncy3GVEMPIOJwD7t0mO2KfYGMgkIg/0, createdBy=86081727811, createdName=4546wk, createdTime=Wed Jul 20 23:30:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93974, encodeId=8299939e437, content=值得一看, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zGdN1x8J6HqtUI2Gpibk3sfIIBhZchAhjoiaCQlficdtQTnEqYncy3GVEMPIOJwD7t0mO2KfYGMgkIg/0, createdBy=86081727811, createdName=4546wk, createdTime=Wed Jul 20 23:30:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93961, encodeId=6a6993961a2, content=普及知识,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160803/IMG57A185CE577478201.jpg, createdBy=bad41730551, createdName=小青虫, createdTime=Wed Jul 20 21:33:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93949, encodeId=70f8939498e, content=学习学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jul 20 21:25:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93872, encodeId=6f06938e204, content=好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Jul 20 19:10:00 CST 2016, time=2016-07-20, status=1, ipAttribution=)]
    2016-08-06 ghy_happy

    值得学习和分享

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=102516, encodeId=1b681025164a, content=学习了,原来肠溶片是这个原理的 <br> , beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2b11940953, createdName=可以肥下去, createdTime=Tue Aug 23 10:10:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96768, encodeId=b07996e6812, content=很好学习了,就是想详细了解关于其他剂型和溶媒啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRtNT7AWKboIfjpeY6Nw6lNxAc4w1aibutHSqCJ2c3AbwfqpRia4IrnzU2mK3Ojx2Har8AUUyhC0kl7/0, createdBy=ecc31722157, createdName=1decafd9m46(暂无匿称), createdTime=Sun Aug 07 17:45:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96279, encodeId=06a2962e9cc, content=值得学习和分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b2c1297487, createdName=ghy_happy, createdTime=Sat Aug 06 07:27:00 CST 2016, time=2016-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=94489, encodeId=7d8d9448988, content=肠溶片的原理让人印象深刻。, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59301669806, createdName=诊艾, createdTime=Sun Jul 24 16:09:00 CST 2016, time=2016-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284405, encodeId=379b1284405d0, content=<a href='/topic/show?id=3db5445e031' target=_blank style='color:#2F92EE;'>#奥美拉唑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44570, encryptionId=3db5445e031, topicName=奥美拉唑)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ced3193, createdName=freve, createdTime=Fri Jul 22 05:48:00 CST 2016, time=2016-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93973, encodeId=7c99939e3fd, content=普及知识,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zGdN1x8J6HqtUI2Gpibk3sfIIBhZchAhjoiaCQlficdtQTnEqYncy3GVEMPIOJwD7t0mO2KfYGMgkIg/0, createdBy=86081727811, createdName=4546wk, createdTime=Wed Jul 20 23:30:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93974, encodeId=8299939e437, content=值得一看, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zGdN1x8J6HqtUI2Gpibk3sfIIBhZchAhjoiaCQlficdtQTnEqYncy3GVEMPIOJwD7t0mO2KfYGMgkIg/0, createdBy=86081727811, createdName=4546wk, createdTime=Wed Jul 20 23:30:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93961, encodeId=6a6993961a2, content=普及知识,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160803/IMG57A185CE577478201.jpg, createdBy=bad41730551, createdName=小青虫, createdTime=Wed Jul 20 21:33:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93949, encodeId=70f8939498e, content=学习学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jul 20 21:25:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93872, encodeId=6f06938e204, content=好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Jul 20 19:10:00 CST 2016, time=2016-07-20, status=1, ipAttribution=)]
    2016-07-24 诊艾

    肠溶片的原理让人印象深刻。

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=102516, encodeId=1b681025164a, content=学习了,原来肠溶片是这个原理的 <br> , beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2b11940953, createdName=可以肥下去, createdTime=Tue Aug 23 10:10:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96768, encodeId=b07996e6812, content=很好学习了,就是想详细了解关于其他剂型和溶媒啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRtNT7AWKboIfjpeY6Nw6lNxAc4w1aibutHSqCJ2c3AbwfqpRia4IrnzU2mK3Ojx2Har8AUUyhC0kl7/0, createdBy=ecc31722157, createdName=1decafd9m46(暂无匿称), createdTime=Sun Aug 07 17:45:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96279, encodeId=06a2962e9cc, content=值得学习和分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b2c1297487, createdName=ghy_happy, createdTime=Sat Aug 06 07:27:00 CST 2016, time=2016-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=94489, encodeId=7d8d9448988, content=肠溶片的原理让人印象深刻。, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59301669806, createdName=诊艾, createdTime=Sun Jul 24 16:09:00 CST 2016, time=2016-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284405, encodeId=379b1284405d0, content=<a href='/topic/show?id=3db5445e031' target=_blank style='color:#2F92EE;'>#奥美拉唑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44570, encryptionId=3db5445e031, topicName=奥美拉唑)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ced3193, createdName=freve, createdTime=Fri Jul 22 05:48:00 CST 2016, time=2016-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93973, encodeId=7c99939e3fd, content=普及知识,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zGdN1x8J6HqtUI2Gpibk3sfIIBhZchAhjoiaCQlficdtQTnEqYncy3GVEMPIOJwD7t0mO2KfYGMgkIg/0, createdBy=86081727811, createdName=4546wk, createdTime=Wed Jul 20 23:30:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93974, encodeId=8299939e437, content=值得一看, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zGdN1x8J6HqtUI2Gpibk3sfIIBhZchAhjoiaCQlficdtQTnEqYncy3GVEMPIOJwD7t0mO2KfYGMgkIg/0, createdBy=86081727811, createdName=4546wk, createdTime=Wed Jul 20 23:30:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93961, encodeId=6a6993961a2, content=普及知识,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160803/IMG57A185CE577478201.jpg, createdBy=bad41730551, createdName=小青虫, createdTime=Wed Jul 20 21:33:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93949, encodeId=70f8939498e, content=学习学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jul 20 21:25:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93872, encodeId=6f06938e204, content=好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Jul 20 19:10:00 CST 2016, time=2016-07-20, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=102516, encodeId=1b681025164a, content=学习了,原来肠溶片是这个原理的 <br> , beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2b11940953, createdName=可以肥下去, createdTime=Tue Aug 23 10:10:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96768, encodeId=b07996e6812, content=很好学习了,就是想详细了解关于其他剂型和溶媒啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRtNT7AWKboIfjpeY6Nw6lNxAc4w1aibutHSqCJ2c3AbwfqpRia4IrnzU2mK3Ojx2Har8AUUyhC0kl7/0, createdBy=ecc31722157, createdName=1decafd9m46(暂无匿称), createdTime=Sun Aug 07 17:45:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96279, encodeId=06a2962e9cc, content=值得学习和分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b2c1297487, createdName=ghy_happy, createdTime=Sat Aug 06 07:27:00 CST 2016, time=2016-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=94489, encodeId=7d8d9448988, content=肠溶片的原理让人印象深刻。, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59301669806, createdName=诊艾, createdTime=Sun Jul 24 16:09:00 CST 2016, time=2016-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284405, encodeId=379b1284405d0, content=<a href='/topic/show?id=3db5445e031' target=_blank style='color:#2F92EE;'>#奥美拉唑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44570, encryptionId=3db5445e031, topicName=奥美拉唑)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ced3193, createdName=freve, createdTime=Fri Jul 22 05:48:00 CST 2016, time=2016-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93973, encodeId=7c99939e3fd, content=普及知识,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zGdN1x8J6HqtUI2Gpibk3sfIIBhZchAhjoiaCQlficdtQTnEqYncy3GVEMPIOJwD7t0mO2KfYGMgkIg/0, createdBy=86081727811, createdName=4546wk, createdTime=Wed Jul 20 23:30:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93974, encodeId=8299939e437, content=值得一看, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zGdN1x8J6HqtUI2Gpibk3sfIIBhZchAhjoiaCQlficdtQTnEqYncy3GVEMPIOJwD7t0mO2KfYGMgkIg/0, createdBy=86081727811, createdName=4546wk, createdTime=Wed Jul 20 23:30:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93961, encodeId=6a6993961a2, content=普及知识,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160803/IMG57A185CE577478201.jpg, createdBy=bad41730551, createdName=小青虫, createdTime=Wed Jul 20 21:33:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93949, encodeId=70f8939498e, content=学习学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jul 20 21:25:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93872, encodeId=6f06938e204, content=好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Jul 20 19:10:00 CST 2016, time=2016-07-20, status=1, ipAttribution=)]
    2016-07-20 4546wk

    普及知识,学习

    0

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    2016-07-20 4546wk

    值得一看

    0

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    2016-07-20 小青虫

    普及知识,学习

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=102516, encodeId=1b681025164a, content=学习了,原来肠溶片是这个原理的 <br> , beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2b11940953, createdName=可以肥下去, createdTime=Tue Aug 23 10:10:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96768, encodeId=b07996e6812, content=很好学习了,就是想详细了解关于其他剂型和溶媒啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRtNT7AWKboIfjpeY6Nw6lNxAc4w1aibutHSqCJ2c3AbwfqpRia4IrnzU2mK3Ojx2Har8AUUyhC0kl7/0, createdBy=ecc31722157, createdName=1decafd9m46(暂无匿称), createdTime=Sun Aug 07 17:45:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96279, encodeId=06a2962e9cc, content=值得学习和分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b2c1297487, createdName=ghy_happy, createdTime=Sat Aug 06 07:27:00 CST 2016, time=2016-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=94489, encodeId=7d8d9448988, content=肠溶片的原理让人印象深刻。, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59301669806, createdName=诊艾, createdTime=Sun Jul 24 16:09:00 CST 2016, time=2016-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284405, encodeId=379b1284405d0, content=<a href='/topic/show?id=3db5445e031' target=_blank style='color:#2F92EE;'>#奥美拉唑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44570, encryptionId=3db5445e031, topicName=奥美拉唑)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ced3193, createdName=freve, createdTime=Fri Jul 22 05:48:00 CST 2016, time=2016-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93973, encodeId=7c99939e3fd, content=普及知识,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zGdN1x8J6HqtUI2Gpibk3sfIIBhZchAhjoiaCQlficdtQTnEqYncy3GVEMPIOJwD7t0mO2KfYGMgkIg/0, createdBy=86081727811, createdName=4546wk, createdTime=Wed Jul 20 23:30:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93974, encodeId=8299939e437, content=值得一看, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zGdN1x8J6HqtUI2Gpibk3sfIIBhZchAhjoiaCQlficdtQTnEqYncy3GVEMPIOJwD7t0mO2KfYGMgkIg/0, createdBy=86081727811, createdName=4546wk, createdTime=Wed Jul 20 23:30:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93961, encodeId=6a6993961a2, content=普及知识,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160803/IMG57A185CE577478201.jpg, createdBy=bad41730551, createdName=小青虫, createdTime=Wed Jul 20 21:33:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93949, encodeId=70f8939498e, content=学习学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jul 20 21:25:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93872, encodeId=6f06938e204, content=好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Jul 20 19:10:00 CST 2016, time=2016-07-20, status=1, ipAttribution=)]
    2016-07-20 1dd8c52fm63(暂无匿称)

    学习学习!

    0

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    2016-07-20 doctorJiangchao

    好文章

    0

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