PLoS Med:空气污染会增加缺血性卒中风险?

2018-11-22 佚名 环球医学网

发表于《PLoS Med》上的一项研究,表明了环境空气污染水平短暂增加可升高缺血性卒中风险。

发表于《PLoS Med》上的一项研究,表明了环境空气污染水平短暂增加可升高缺血性卒中风险。

背景:环境空气污染对低和中等收入国家缺血性卒中风险短期影响的证据有限且不一致。研究者旨在检测空气污染和中国因缺血性卒中引起的每天住院率之间的相关性。

方法和结果:研究者从全国数据库中鉴别出2014~2016年缺血性卒中的住院数据。该数据库覆盖了高达2亿8000万接受中国城镇职工基本医疗保险(UEBMI)的参保者。研究者使用两阶段法检测了空气污染和每天因缺血性卒中住院率之间的相关性。泊松时间序列回归模型首次用于评估空气污染在每座城市中的影响。然后进行了随机效应Meta分析来组合评估值。Meta回归模型用于探讨潜在的效应影响因素。

在中国172个城市中鉴别出超过200万缺血性卒中住院者。单污染模型中,空气动力学直径<2.5μm的颗粒物(PM2.5)、二氧化硫(SO2)、二氧化氮(NO2)、臭氧(O3)浓度每增加10μg/m3和一氧化碳(CO)浓度每增加1mg/m3,分别与每天缺血性卒中住院增加0.34%(95% CI,0.20~0.48)、1.37%(1.05~1.70)、1.82%(1.45~2.19)、0.01%(-0.14~0.16)和3.24%(2.05~4.43)相关。SO2和NO2的相关性在双污染模型中仍然显着,但是PM2.5和CO的相关性并非如此。在具有较低空气污染水平和较高气温的城市中,以及老年亚组中,该效应估计值较高。本研究的主要局限性为,环境空气污染个体暴露数据的不可及。

结论:作为中国首个系统检测环境空气污染短期暴露和缺血性卒中之间相关性的全国性研究,结果表明空气污染水平短暂增加可增加缺血性卒中风险,这对降低中国缺血性卒中负担具有显着的公共卫生意义。

原始出处:
Tian Y1, Liu H1,2, Zhao Z3,et al.Association between ambient air pollution and daily hospital admissions for ischemic stroke: A nationwide time-series analysis.PLoS Med. 2018 Oct 4;15(10):e1002668. doi: 10.1371/journal.pmed.1002668. eCollection 2018 Oct.

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    2018-11-24 hb2008ye
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    2018-11-22 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2018-11-22 guging

    中风是俗称,应该称为缺血性卒中吧

    0

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PNAS & Plos One :空气污染会导致认知能力下降,还会威胁肾脏?

来自北京师范大学、耶鲁大学和北京大学的三位研究人员发现,空气污染与人类认知能力下降之间存在关联。他们的这项研究发表在8月27日的《美国国家科学院院刊》上,三位研究人员分别是Xin Zhang, Xi Chen和Xiaobo Zhang,他们在PNAS上个描述了在研究中取得的发现。

BMJ Open:研究显示空气污染关联老年痴呆症高风险,以汽车尾气为主

英国伦敦大学人口健康研究所一项研究显示,城市空气污染,以汽车尾气为主,关联老年痴呆症风险增高。这一研究结果由最新一期《英国医学杂志·公开》期刊刊载。

Environ Sci Technol Lett:美研究称:空气污染让国人减寿约1.3年,减少污染可增寿0.76岁

雾霾,国人已深受其扰。一提雾霾就不能不提其中漂浮着的PM2.5,这些小颗粒可以深入人体,与心血管病、脑卒中、呼吸系统疾病和癌症等疾病风险都脱不开干系。

AHA2018 :居住于可步行性好的街区获益可抵消空气污染相关影响

近年来,人们越来越关注空气污染对健康的影响。既往研究提示,居住在更适合步行的街区有助于鼓励人们进行身体活动从而对高血压及糖尿病等心血管疾病危险因素发挥保护作用。