JAHA:老年女性久坐行为与心房颤动的关系

2022-03-08 MedSci原创 MedSci原创

在这项针对居住在社区的老年女性的前瞻性研究中,总久坐时间和久坐久坐模式与较高的心房颤动风险相关,但这些关联因身体机能和自我报告的健康状况的调整而有所减弱。

心房颤动是美国最常见的心律失常,是卒中和死亡率的独立预测因子。久坐行为与心血管疾病相关,但其与心房颤动之间的相关性尚未得到很好的研究。

近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员的目的是评估客观测量的久坐行为与心房颤动事件之间的关联。

研究人员通过佩戴在腰带上1周的三轴加速度计测量了受试者的久坐行为。心房颤动事件是从医疗保险索赔中确定的。研究人员使用针对人口统计学和临床协变量调整的Cox比例风险模型评估了总久坐时间(或久坐行为模式)与心房颤动事件之间的关联。

在2675名参与者(平均年龄为78.2岁)中,有268名(10.0%)受试者发生心房颤动,发病率为每1000人每年31例。在调整年龄、种族和民族、体重指数、教育、吸烟史、高血压糖尿病、卒中、心脏病和其他慢性病后,更长的总久坐时间与更高的心房颤动风险相关(第4四分位数与第1四分位数相比的风险比为1.20,[95%CI为0.81-1.78];趋势P=0.05)。在调整身体机能和自评健康后,这一相关性不再具有统计学意义。更长的平均久坐时间和更连续的久坐时间(相对于久坐时间的频繁休息)也与更高的心房颤动风险相关,但这些关联也随着连续调整而有所减弱。

在这项针对居住在社区的老年女性的前瞻性研究中,总久坐时间和久坐久坐模式与较高的心房颤动风险相关,但这些关联因身体机能和自我报告的健康状况的调整而有所减弱。这表明久坐行为与心房颤动之间的关联可能归因于对整体功能和健康。

原始出处:

Brian C. Boursiquot.et al.Sedentary Behavior and Atrial Fibrillation in Older Women: The OPACH Study.JAHA.2022.https://www.ahajournals.org/doi/10.1161/JAHA.121.023833

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    2022-03-09 zhaohui6731
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    2022-03-09 sodoo
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    2022-03-08 光明骑士

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1268791, encodeId=59f81268e9154, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Wed Mar 09 12:42:58 CST 2022, time=2022-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626984, encodeId=c1f41626984d6, content=<a href='/topic/show?id=986a5101e46' target=_blank style='color:#2F92EE;'>#心房#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51017, encryptionId=986a5101e46, topicName=心房)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=20ba21064884, createdName=sodoo, createdTime=Wed Mar 09 12:42:58 CST 2022, time=2022-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1200537, encodeId=13f1120053e7f, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4d585243593, createdName=光明骑士, createdTime=Tue Mar 08 13:25:59 CST 2022, time=2022-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1200523, encodeId=a72d12005238b, content=好文章,值得一读。, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJlfgys76DEiaNtbYo2re3ibjrUPTRibEXRyFwAB4aAGiave842S0FQDf0wAoaH226NiaSoPPDzhndsf1g/132, createdBy=88b489038, createdName=yangchou, createdTime=Tue Mar 08 12:40:37 CST 2022, time=2022-03-08, status=1, ipAttribution=)]
    2022-03-08 yangchou

    好文章,值得一读。

    0

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