Crit Care:重症监护病房急性呼吸窘迫综合征的发生率和结局

2020-08-21 MedSci原创 MedSci原创

在中国大陆的18个ICU中,ARDS的发生率很低。死亡率和维持生命治疗的停止率很高。采用指南推荐的肺部保护策略具有较高的依从性,但缺乏辅助治疗。这些结果表明在中国仍有巨大的潜能来改善ARDS患者的治疗

近日,危重病医学领域权威杂志Critical Care上发表了一篇研究文章,该研究旨在评估医学/呼吸重症监护病房(MICU / RICU)中急性呼吸窘迫综合征(ARDS)的发生率和死亡率,以评估中国大陆地区符合柏林标准的ARDS患者在常规临床实践中的通气管理和辅助治疗的情况。

这是一项多中心的前瞻性纵向研究,纳入了符合柏林标准的ARDS患者。研究人员收集了受试者基线数据以及有关呼吸机治疗和辅助疗法的数据。

在研究期间,入组ICU的18793例患者中,672例符合柏林ARDS标准,527例ARDS患者被纳入分析。在402(77.0%)位患者中,ARDS的最常见诱因是肺炎。轻度ARDS的患病率为9.7%(51/527),中度ARDS的患病率为47.4%(250/527),重度ARDS的患病率为42.9%(226/527)。总共有400名(75.9%)患者在入住ICU期间接受了有创机械通气。所有ARDS患者的潮气量为6.8(5.8-7.9)mL/kg,终末正压(PEEP)为8(6-12)cmH2O。分别对61名(15.3%)和85名(16.1%)的通气患者进行了肺复张(RMs)和俯卧位。92名(17.5%)患者停止了维持生命的治疗。将这些患者纳入死亡率分析后,244名(46.3%)ARDS患者(轻度ARDS患者16人(31.4%),中度ARDS患者101人(40.4%)和重度ARDS患者127人(56.2%) )在医院内死亡。

在中国大陆的18个ICU中,ARDS的发生率很低。死亡率和维持生命治疗的停止率很高。采用指南推荐的肺部保护策略具有较高的依从性,但缺乏辅助治疗。这些结果表明在中国仍有巨大的潜能来改善ARDS患者的治疗。

原始出处:

Xu Huang.et al.Incidence and outcomes of acute respiratory distress syndrome in intensive care units of mainland China: a multicentre prospective longitudinal study.Critical Care.2020.https://ccforum.biomedcentral.com/articles/10.1186/s13054-020-03112-0

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    2020-09-12 lovetcm

    #重症监护#病房急性#呼吸窘迫综合征#的发生率和结局,应该是随着时间不同而不一样,随着时间变化,救治水平不断提升

    0

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    2020-08-23 彭红

    体外膜肺技术提高重度ARDS患者的生存率

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    2020-08-23 bioon6
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