J Cardiovasc Electr:不良心血管结局伴房颤的心电图特征

2016-05-25 MedSci MedSci原创

ECG和房颤患者的心血管结局:12导联心电图的标准参数(如QRS间期和PR、JT、QT间期等)与有房颤病史患者的不良心血管结局(心血管死亡、全因死亡、心律失常死亡率和住院)之间的关系既往还无相关报道。一个汇总分析随机纳入了AFFIRM和AF-CHF试验的5436例患者,平均年龄68.2±8.3,其中34.8%为女性,有非永久性房颤的病史。采用多元Cox回归模型评价房颤(AF)和窦性心律的ECG参数

ECG和房颤患者的心血管结局:12导联心电图的标准参数(如QRS间期和PR、JT、QT间期等)与有房颤病史患者的不良心血管结局(心血管死亡、全因死亡、心律失常死亡率和住院)之间的关系既往还无相关报道。

一个汇总分析随机纳入了AFFIRM和AF-CHF试验的5436例患者,平均年龄68.2±8.3,其中34.8%为女性,有非永久性房颤的病史。采用多元Cox回归模型评价房颤(AF)和窦性心律的ECG参数的预测值。

随访时间40.8±16.3月,QRS间期>120ms与全因死亡(房颤:危险比[HR]=1.46, 95%CI[1.21–1.76],P<0.001)、心血管死亡(窦性心律:HR=1.75, 95%CI[1.15-2.65],P=0.009;房颤:HR=1.56, 95%CI[1.27-1.93],P<0.001)、心律失常死亡(窦性心律:HR=1.90, 95%CI[1.09-3.32],P=0.024;房颤:HR=1.84, 95%CI[1.35-2.51],P<0.001)、住院(房颤:HR=1.15, 95%CI[1.02-1.29],P=0.027)和心血管事件住院(房颤:HR=1.21, 95%CI[1.06-1.37],P=0.004)均独立相关。PR间期增加(>200ms)与心血管死亡(HR=1.56, 95%CI[1.11-2.21],P=0.010)、心律失常死亡(HR=1.91, 95%CI[1.14-3.18],P=0.004)独立相关。JT间期和QTc间期对死亡预测无统计学意义。

因此,ECG的标准参数对于有房颤病史患者的不良心血管结局是十分有价值的。

原始出处:

Andrade JG,Roy D,Wyse G,et al.ECG Features Associated With Adverse Cardiovascular Outcomes in Patients With Atrial Fibrillation.J Cardiovasc Electrophysiol. 2016;27(4):404-413. 

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    2017-03-20 quxin068
  2. [GetPortalCommentsPageByObjectIdResponse(id=1938549, encodeId=3fb7193854906, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Mar 20 02:06:00 CST 2017, time=2017-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87652, encodeId=902e8e652e4, content=好文章!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f9f21613855, createdName=lsblb, createdTime=Mon May 30 18:56:00 CST 2016, time=2016-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87653, encodeId=63408e65321, content=好文章!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f9f21613855, createdName=lsblb, createdTime=Mon May 30 18:56:00 CST 2016, time=2016-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269302, encodeId=6e7712693022b, content=<a href='/topic/show?id=49d1518915a' target=_blank style='color:#2F92EE;'>#心血管结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51891, encryptionId=49d1518915a, topicName=心血管结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7a9987, createdName=gous, createdTime=Fri May 27 08:06:00 CST 2016, time=2016-05-27, status=1, ipAttribution=)]
    2016-05-30 lsblb

    好文章!!

    0

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    2016-05-30 lsblb

    好文章!!

    0

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