Heart:早期中国大饥荒暴露可能增加心脑血管疾病风险

2020-01-12 不详 MedSci原创

本研究的目的旨在评估中国大饥荒产前经历对中年慢性病风险的潜在影响。本研究纳入分析了92284名39-51岁出生在中国大饥荒时代的无主要慢性疾病的对象,并将其分成非饥荒出生组合饥荒出生组,结局事件包括心血管疾病、癌症和呼吸系统疾病的发生。经过平均10.1年时间的随访,有4626名对象出现缺血性心脏病,7332名出现脑血管疾病,3111名出现癌症,16081名出现呼吸系统疾病。在整体人群中,出生前饥荒

本研究的目的旨在评估中国大饥荒产前经历对中年慢性病风险的潜在影响。

本研究纳入分析了92284名39-51岁出生在中国大饥荒时代的无主要慢性疾病的对象,并将其分成非饥荒出生组合饥荒出生组,结局事件包括心血管疾病、癌症和呼吸系统疾病的发生。经过平均10.1年时间的随访,有4626名对象出现缺血性心脏病,7332名出现脑血管疾病,3111名出现癌症,16081名出现呼吸系统疾病。在整体人群中,出生前饥荒的暴露不与成年期慢性疾病的发生相关。然而,在城市人群中,与非饥荒组参与者相比,饥荒组的脑血管疾病风险更高(HR 1.18; 95% CI 1.09-1.28),这种相关性在农村人群中不存在。

研究结果显示,出生前暴露于大饥荒中可能增加心脑血管疾病风险,而这种风险可能被生活方式改变。

原始出处:

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    2020-05-06 drj2003
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    2020-01-14 zhaojie88
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    2020-01-14 slcumt

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