Calypso Biotech获得2000万欧元融资以开发IL-15单抗治疗自身免疫性疾病

2019-02-20 不详 MedSci原创

Calypso Biotech公司,作为自身免疫性疾病的治疗性抗体开发的新兴领导者,今天宣布获得2000万欧元的A轮融资。该融资轮次的收益将支持Calypso Biotech的抗白细胞介素-15(IL-15)抗体CALY-002的开发,用于治疗多种自身免疫性疾病。

Calypso Biotech公司,作为自身免疫性疾病单抗开发的新兴领导者,今天宣布获得2000万欧元的A轮融资。该融资的收益将支持Calypso Biotech的抗白细胞介素-15(IL-15)抗体CALY-002的开发,用于治疗多种自身免疫性疾病。

IL-15是一种免疫检查点细胞因子,可调控炎症以及多种组织驻留免疫细胞,最近在肿瘤免疫学领域备受关注。IL-15被认为是组织驻留记忆T细胞存活的关键因素,T细胞是参与疾病维持和复发的免疫细胞。Calypso Biotech科学家认为,靶向组织驻留记忆T细胞具有超越传统细胞因子干预方法的显着优势,并可提供前所未有的疾病改善效果。

Calypso Biotech已选择在嗜酸性粒细胞性食管炎(EoE)以及其他未公开的自身免疫适应症中开发CALY-002。EoE是一种严重且使人衰弱的免疫相关的食道慢性疾病,是成人吞咽困难的第二大原因。

CALY-002治疗EoE已经获得欧洲药品和食品和药品管理局的孤儿药指定。

原始出处:


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    2020-01-28 cathymary
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    2019-12-11 wetgdt
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    2019-09-06 shock_melon
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    2019-04-22 sunylz
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    2019-02-22 zhao4618
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    2019-02-22 jjjiang0202
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    2019-02-20 CHANGE

    又是钱!医学需要投资呀,赞!

    0

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