ARD:血尿酸盐正常高限也增高血压风险(CARDIA研究)

2012-10-03 薛夏沫 中国医学论坛报

  美国一项研究显示,即使低于传统高尿酸血症阈值(6.8 mg/dl),血尿酸盐浓度较高亦与未来发生高血压显著相关。论文9月14日在线发表于《风湿病年鉴》(Ann Rheum Dis)。   研究纳入青年冠状动脉危险因素研究(CARDIA)中4752名基线时无高血压者的血清尿酸数据,自1985年起随访20年。结果为,基线时男、女的平均年龄为24.8和24.9岁。与参

  美国一项研究显示,即使低于传统高尿酸血症阈值(6.8 mg/dl),血尿酸盐浓度较高亦与未来发生高血压显著相关。论文9月14日在线发表于《风湿病年鉴》(Ann Rheum Dis)。

  研究纳入青年冠状动脉危险因素研究(CARDIA)中4752名基线时无高血压者的血清尿酸数据,自1985年起随访20年。结果为,基线时男、女的平均年龄为24.8和24.9岁。与参考组相比,男性和女性的初始血尿酸盐水平为5.8 mg/dl和3.6 mg/dl时,出现高血压的风险较高;血尿酸盐水平每升高1 mg/dl,男性患高血压风险增加25%,但女性无显著增加。

原始文献:

Gaffo AL, Jacobs DR Jr, Sijtsma F, Lewis CE, Mikuls TR, Saag KG. Serum urate association with hypertension in young adults: analysis from the Coronary Artery Risk Development in Young Adults cohort. Ann Rheum Dis. 2012 Sep 14



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    2016-03-25 180****7709(上善若水)

    不能明确血尿酸高是保护因素还是风险因素

    0

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    2012-10-05 quxin068
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    2012-10-05 liuxiaona
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    2012-10-05 liuxiaona

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