JAMA Neurol:高血压在黑人群体晚年痴呆风险中扮演重要角色

2020-04-14 MedSci原创 MedSci原创

较高的血压水平或是黑人群体晚年认知能力下降的原因之一。

统计发现,黑人群体的痴呆风险高于白人更容易患痴呆症,而黑人群体的高血压发病率较高,近日研究人员考察了血压(bp)在黑人高痴呆风险中扮演的角色。

研究收集了5个队列研究参与者数据,研究时间从1971年到2017年,平均随访12.4年。研究的主要终点为认知改变,次要结果是记忆和执行能力变化。

19378名基线无中风和痴呆症参与者,首次认知评估的平均年龄为59.8,参与者中,女性10724人(55.3%),白人15526人(80.1%)。与白人相比,黑人的整体认知能力(每年下降0.03点)和记忆力下降速度明显更快(每年下降0.08点),但执行功能下较慢(每年下降0.09点)。时间相关的累积平均收缩压水平与整体认知(血压每增加10毫米汞柱,每年下降0.018点)、记忆力(每增加10毫米汞柱,每年下降0.028点)和执行能力(每增加10毫米汞柱,每年下降0.01点)地显著快速下降相关。调整累积平均收缩压后,黑人和白人在整体认知(-0.01点/年)和记忆方面(-0.06点/年)的差异减弱,但在执行能力方面(0.10分/年)没有变化。

研究认为,较高的血压水平或是黑人群体晚年认知能力下降的原因之一。

原始出处:

Deborah A. Levine et al. Association Between Blood Pressure and Later-Life Cognition Among Black and White Individuals.JAMA Neurol. April 13, 2020.

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    2020-07-25 xjy13
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    2021-01-28 yinhl1978
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    2020-04-14 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1814883, encodeId=53741814883ec, content=<a href='/topic/show?id=9e8c960e361' target=_blank style='color:#2F92EE;'>#重要角色#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96073, encryptionId=9e8c960e361, topicName=重要角色)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=af68384, createdName=hanhaisha2008, createdTime=Sun Oct 18 14:01:44 CST 2020, time=2020-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1717030, encodeId=1b5b1e170308b, content=<a href='/topic/show?id=f8a98002eb1' target=_blank style='color:#2F92EE;'>#群体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80027, encryptionId=f8a98002eb1, topicName=群体)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6c0832353243, createdName=xjy13, createdTime=Sat Jul 25 15:01:44 CST 2020, time=2020-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2001020, encodeId=a3a820010206c, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Thu Jan 28 16:01:44 CST 2021, time=2021-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1316748, encodeId=a60a1316e4897, content=<a href='/topic/show?id=d3d0e121576' target=_blank style='color:#2F92EE;'>#痴呆风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71215, encryptionId=d3d0e121576, topicName=痴呆风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a98f453, createdName=pcw106, createdTime=Thu Apr 16 10:01:44 CST 2020, time=2020-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036034, encodeId=c33d10360348c, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Tue Apr 14 22:01:44 CST 2020, time=2020-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048612, encodeId=e63810486120a, content=老年人痴呆何药可用??, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Tue Apr 14 22:01:44 CST 2020, time=2020-04-14, status=1, ipAttribution=)]
    2020-04-14 junJUN

    老年人痴呆何药可用??

    0

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