2021美国癌症死亡率大幅下降,我们能学到哪些预防癌症绝招?

2021-01-19 MedSci原创 MedSci原创

根据世界卫生组织国际癌症研究机构(IARC)最新发布的《2020年全球最新癌症负担数据》显示:2020年全球新发癌症病例1929万例,其中中国新发癌症457万人,占全球23.7%,高居全球第一!

根据世界卫生组织国际癌症研究机构(IARC)最新发布的《2020年全球最新癌症负担数据》显示:2020年全球新发癌症病例1929万例,其中中国新发癌症457万人,占全球23.7%,高居全球第一!死亡人数突破300万,详细见:2020最新全球癌症数据:乳腺癌取代肺癌,成为全球第一大癌,中国年癌症死亡人数突破300万

美国癌症5年生存率高达67%(详细见:美国癌症统计2021:新增189万例,死亡60万例,死亡率连续第二年大幅下降),据最新的《中国居民营养与慢性病状况报告(2020)年》,中国的癌症5年生存率为40.5%,与美国相比尚有不小的差距。据国家癌症中心主任赫捷院士介绍,我国的癌症5年生存率与发达国家相比的差距主要原因是,一方面中国癌症发病的前几位恶性肿瘤大部分是预后比较差的,如肺癌、食管癌、胃癌、肝癌等。另一方面,中国癌症筛查和早诊早治覆盖人群还相对比较少,大众主动参加防癌体检的意识还不够强,大多数患者在发现癌症的时候就已经是中晚期了,因此治疗效果比较差。此外,临床规范化诊治以及同质化水平,还需要进一步提高。

在全球肺癌发病率和死亡率总体呈增长趋势的形势下,美国2021年癌症统计报告出炉,死亡率连续2年大幅度下降!为什么美国能让肺癌在内的几大癌症死亡率逐年下降,我们能学到哪些防癌的绝招呢?

一、癌症筛查

癌症早期筛查技术的完善和推广,让更多的癌症患者在早期发现及时给与干预和治疗,提高整体的五年生存率。

1、前列腺癌---5年生存率约为99%!

2、甲状腺癌----5年生存率大约为98%!(取决于不同的组织类型)

3、睾丸癌---5年生存率大约为95.1%!

4、黑色素瘤---5年生存率约为91.7%!

5、早期乳腺癌----早期(0期和1期)5年生存率:99%-100%!

1、提前15年体检,建议在35岁以上应该每年定期体检

有肿瘤遗传家族史的人,除了一般体检外,一定要在比直系亲属的患癌年龄早15~20年时去肿瘤专科医院或科室做防癌体检。比如,直系亲属55岁查出癌症,那么你在35~40岁的时候就应该启动防癌体检。

人乳头瘤病毒(HPV)测试可以早期发现宫颈癌。

在许多高收入国家,乳腺X线筛查(钼靶)减少了乳腺癌死亡率。

粪便潜血试验筛查降低了临床试验中结直肠癌的死亡率。

低剂量螺旋CT扫描可以降低肺癌死亡率和降低死亡率。

定期胃肠镜检查,可以降低胃癌和结直肠癌的死亡率。

2、40岁以上最要留意

40岁以上人群,患癌风险明显加大,需要更加重视癌症的定期筛查。

二、严控主要的风险因素

1、禁烟

美国每年由于癌症去世的人里,肺癌占了1/4以上。60年代开始的控烟运动,吸烟人数40年持续降低,而且公共场合全面禁烟继对吸烟时间、地点做出了严格法律限制,从1990年到现在,成人吸烟率从42.4%降到了16.8%,死于肺癌的男性降低了45%,女性降低了19%。

吸烟的下降直接使与烟草相关的癌症(包括肺癌,喉癌和膀胱癌)的发病率和死亡率降低,以及总体发病率和死亡率。

2、控制体重

体重过高与至少13种癌症的风险增加相关,包括结肠直肠癌,绝经后乳腺癌和晚期前列腺癌。

研究发现,超重与乳腺癌,前列腺癌和结肠直肠癌患者的生存较差有关。体重增加可导致约8%的癌症病例和7%的癌症死亡。相关报道:孟德尔随机化表示:肥胖相关的癌症风险被低估了!

3、增加运动

据估计,在美国所有新癌症病例中,有3%(2014年为46,300例)可归因于体力活动不足。体育锻炼可以降低结直肠癌,乳腺癌和子宫内膜癌的风险。进行体育锻炼可以改善癌症幸存者与健康相关的生活质量。相关报道见:美国癌症报告出炉:运动不足 癌症可能会找上门

4、控制饮酒

饮酒可导致至少六种癌症的发展,包括:结肠癌,直肠癌,女性乳腺癌,头颈癌和食道癌。‍相关报道见:适度喝酒有益健康?研究揭示:五种癌症和酒精直接有关

5、保持心情开朗

良好的心情,有助于人体免疫功能等发挥,过度焦虑,甚至抑郁,会引发诸多疾病,相关报道见:Nature子刊:情绪影响癌症治疗效果?难怪乐观的人活得久

6、健康饮食

健康饮食,还能减少肥胖发生,从另外角度减少癌症的风险。象地中海饮食,一直被认为是健康饮食的最佳选择之一,相关报道:AJCN:地中海饮食或可降低结直肠癌的发病率Clin Nutrition:饮食不健康和久坐行为与癌症生存率有关

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    2021-03-02 ms2000000050996988

    早发现早治疗

    0

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    2021-01-21 jeanqiuqiu
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    2021-01-20 kun

    学习了

    0

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    2021-01-20 Jessica

    35岁以后就需要定期体检,对于女性来说,一定要做HPV测试。

    0

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    2021-01-19 中华911

    触目惊心,我辈还需努力!

    0

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    2021-01-19 棒棒医学生

    赞!

    0

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    2021-01-19 仁心济世

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免疫检查点抑制剂(ICI)广泛用于各种恶性肿瘤。然而,其在肾移植患者中的安全性和有效性还不明确。

Genes Dev:顾伟实验室解析p53抑癌功能的终极武器——铁死亡和mTOR

众所周知, p53是一个拥有广泛而强大功能的抑癌基因。超过一半的肿瘤患者带有p53突变。p53基因敲除(KO)小鼠会在发育早期就形成肿瘤。

CA Cancer J Clin:2020年美国青少年及年轻人癌症统计报告出炉

美国国家癌症研究所将青少年和年轻人(adolescents and young adults ,AYAs)癌症定义为在15-39岁中确诊的癌症。与老年癌症患者相比,AYAs癌症患者具有更高的长期和晚期

Science| 新的概念:系统回顾**定时治疗癌症

昼夜节律协调人的生化,生理和行为功能的日常节律。在每种情况下,昼夜节律的丧失都会导致生存机会降低。这导致了一个假设,即昼夜节律紊乱会导致疾病。