Diabetes Care:警示:抑郁症状可削弱体育锻炼预防糖尿病的效果

2019-09-15 国际糖尿病编辑部 国际糖尿病

尽管抑郁症状对糖尿病管理的影响已有较为成熟的研究,但其对糖尿病预防的影响尚不明确。研究表明抑郁症状会降低2型糖尿病(T2DM)患者的自我管理水平并影响其健康行为,那么,其是否会降低T2DM预防计划的有效性需要进一步研究明确。近期一项研究结果显示抑郁症状可降低体力活动水平,增加T2DM的风险。该研究发表在近期出版的Diabetes Care上。

尽管抑郁症状对糖尿病管理的影响已有较为成熟的研究,但其对糖尿病预防的影响尚不明确。研究表明抑郁症状会降低2型糖尿病(T2DM)患者的自我管理水平并影响其健康行为,那么,其是否会降低T2DM预防计划的有效性需要进一步研究明确。近期一项研究结果显示抑郁症状可降低体力活动水平,增加T2DM的风险。该研究发表在近期出版的Diabetes Care上。

来自英国莱斯特大学糖尿病研究中心的研究人员整合了2项随机对照研究(远离T2DM研究和与预防T2DM研究)数据。这2项研究均纳入T2DM高风险人群,采用相似的干预方法促进体力活动水平,且均采用 “医院焦虑抑郁量表(Hospital Anxiety and Depression Scale HADS)”评估受试者抑郁水平,分别通过计步器或加速度计记录每日步行行为以评估抑郁症状水平,研究持续3年。最终,纳入分析了1163例受试者(平均年龄65岁,35%女性),试验组为592例,对照组为571例。

研究结果显示,基线时HADS得分中位数为3分;11%受试者为轻度到重度抑郁。相比于对照组,试验组受试者每天多步行363步。基线或随访期间无抑郁症状的受试者多步行592步(P<0.001)。基线时每增加一项抑郁症状得分,每日体力活动水平减少88步(95%CI:21-155步);随访期间,每增加一项抑郁症状得分,每日活动水平再减少99步(95%CI:2-196步)。该研究得出结论,基线时受试者的抑郁症状及随访过程中抑郁症状的变化均会影响体力活动水平,降低T2DM的预防效果。

英国莱斯特大学糖尿病研究中心Thomas Yates教授表示“此研究结果表明抑郁症状与糖尿病预防计划中的体力活动水平减低有关,提示糖尿病预防项目应扩展其内容,可将抑郁症状评估与管理作为核心目标。” 

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    2019-09-16 misszhang

    谢谢MedSci提供最新的资讯

    0

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    2019-09-16 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

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    2019-09-16 jingjing

    运动锻炼应该是健康第一要素,对各类疾病都应该有益。但是国内这方面研究太少

    0

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    2019-09-16 txqjm

    谢谢了,学习

    0

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